Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   BFM96_RS05115 Genome accession   NZ_CP016953
Coordinates   1076118..1076807 (+) Length   229 a.a.
NCBI ID   WP_068991187.1    Uniprot ID   A0A917A5Q0
Organism   Streptococcus himalayensis strain HTS2     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1071118..1081807
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BFM96_RS05095 - 1071566..1072792 (-) 1227 WP_068991179.1 transporter -
  BFM96_RS05100 - 1072913..1073416 (-) 504 WP_229676521.1 hypothetical protein -
  BFM96_RS10830 - 1073486..1073779 (-) 294 WP_083201745.1 helix-turn-helix transcriptional regulator -
  BFM96_RS05105 - 1073862..1074401 (+) 540 WP_068991181.1 DUF177 domain-containing protein -
  BFM96_RS05110 gndA 1074685..1076109 (+) 1425 WP_068991184.1 NADP-dependent phosphogluconate dehydrogenase -
  BFM96_RS05115 covR 1076118..1076807 (+) 690 WP_068991187.1 response regulator transcription factor Regulator
  BFM96_RS11340 - 1076917..1077303 (-) 387 WP_068991190.1 hypothetical protein -
  BFM96_RS05125 - 1077502..1077843 (+) 342 WP_068991194.1 LytTR family DNA-binding domain-containing protein -
  BFM96_RS05130 comE/blpR 1077845..1078582 (+) 738 WP_068991197.1 response regulator transcription factor Regulator
  BFM96_RS05135 - 1078596..1079933 (+) 1338 WP_068991199.1 GHKL domain-containing protein -
  BFM96_RS10840 - 1079984..1080142 (-) 159 WP_083201746.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  BFM96_RS05140 - 1080245..1081597 (-) 1353 WP_068991202.1 bacteriocin secretion accessory protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26762.89 Da        Isoelectric Point: 6.0407

>NTDB_id=194036 BFM96_RS05115 WP_068991187.1 1076118..1076807(+) (covR) [Streptococcus himalayensis strain HTS2]
MGKRILLIEHETNLARFLALELQKEAYQIDRCETGQKGLHLAKENTYDLLLLNYDLLDMTGEEFAESLSLIKPASVIIVM
EERETLPQHLENIQRFAVSYLVKPFIVNDLIDKISAIFRGRDFIDQHCSQMKIPTSYRNLRLDVENHLVYRGDEVIVLTR
REYDLLATLMGSKQVMTREQLLERVWKYESTAETNVVDVYIRYLRGKIDVPNQKSYIKTIRGVGYSMQD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=194036 BFM96_RS05115 WP_068991187.1 1076118..1076807(+) (covR) [Streptococcus himalayensis strain HTS2]
ATGGGAAAGCGGATTTTATTAATTGAACATGAAACAAATTTAGCACGATTCCTAGCGTTAGAGTTGCAAAAGGAAGCCTA
TCAGATTGATCGCTGTGAGACAGGGCAAAAAGGTTTGCACCTTGCCAAAGAAAATACTTATGATTTGCTCTTGCTTAATT
ATGATTTGCTAGATATGACTGGTGAAGAGTTCGCAGAAAGCCTTAGCCTGATAAAACCTGCGAGCGTGATTATCGTCATG
GAAGAGCGAGAAACTCTGCCTCAGCATTTAGAAAATATCCAACGATTTGCGGTTTCTTACCTGGTCAAGCCTTTCATCGT
GAATGATTTGATTGATAAAATTTCTGCCATTTTCCGTGGTCGTGACTTCATTGACCAGCATTGTAGCCAAATGAAAATCC
CAACTTCCTATCGGAATTTACGGCTTGATGTTGAAAATCATCTGGTTTATAGAGGAGACGAGGTCATTGTTTTAACCCGC
AGAGAATATGATTTACTAGCGACCCTTATGGGAAGTAAGCAAGTCATGACCAGAGAGCAATTGCTGGAGCGGGTTTGGAA
ATACGAAAGTACAGCTGAAACCAATGTCGTTGATGTCTATATCCGTTACCTTCGTGGGAAGATTGATGTTCCTAATCAGA
AAAGTTACATCAAAACCATTCGTGGGGTAGGCTACAGCATGCAGGATTAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.614

99.563

0.454

Multiple sequence alignment