Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   BEN15_RS08785 Genome accession   NZ_CP016877
Coordinates   1663864..1665204 (-) Length   446 a.a.
NCBI ID   WP_065973254.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain KLDS 3.1003     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1658864..1670204
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BEN15_RS08750 (BEN15_08745) - 1658982..1659368 (-) 387 WP_002953113.1 DUF1934 domain-containing protein -
  BEN15_RS11865 - 1659460..1660340 (-) 881 Protein_1645 GNAT family N-acetyltransferase -
  BEN15_RS08765 (BEN15_08760) yidA 1660548..1661357 (+) 810 WP_011226081.1 sugar-phosphatase -
  BEN15_RS08770 (BEN15_08765) - 1661359..1662573 (+) 1215 WP_065973253.1 aminoacyltransferase -
  BEN15_RS08775 (BEN15_08770) - 1662625..1662986 (-) 362 Protein_1648 YbaN family protein -
  BEN15_RS08780 (BEN15_08775) vicX 1663046..1663858 (-) 813 WP_011681204.1 MBL fold metallo-hydrolase Regulator
  BEN15_RS08785 (BEN15_08780) vicK 1663864..1665204 (-) 1341 WP_065973254.1 cell wall metabolism sensor histidine kinase VicK Regulator
  BEN15_RS08790 (BEN15_08785) vicR 1665197..1665904 (-) 708 WP_011226084.1 response regulator YycF Regulator
  BEN15_RS08795 (BEN15_08790) - 1666431..1667198 (+) 768 WP_065973255.1 amino acid ABC transporter ATP-binding protein -
  BEN15_RS08800 (BEN15_08795) - 1667210..1668043 (+) 834 WP_002953142.1 transporter substrate-binding domain-containing protein -
  BEN15_RS08805 (BEN15_08800) - 1668061..1668759 (+) 699 WP_065973256.1 amino acid ABC transporter permease -
  BEN15_RS08810 (BEN15_08805) - 1668771..1669421 (+) 651 WP_011226088.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50827.17 Da        Isoelectric Point: 5.3881

>NTDB_id=193327 BEN15_RS08785 WP_065973254.1 1663864..1665204(-) (vicK) [Streptococcus thermophilus strain KLDS 3.1003]
MTSIGLNITSFELALLFMLLFVAFYFIFIAYRDYQQVKNIRKLTKRVKSLMAGNYNEKLYIKGNSELLELANSLNDLSDV
FRLTHENLIQEKNRLSSVLSYMSDGVIATNRLGQITMINSTAQRLLNLDRETATQMSILDILDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALNE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLNVEMTNFTAFMTYILNRFGQIKSQETNPGKSYEIIRDYPVNSI
WVEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDTQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIVKQHNGFIWAKSEYGKGSTFTIVLPYDQDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=193327 BEN15_RS08785 WP_065973254.1 1663864..1665204(-) (vicK) [Streptococcus thermophilus strain KLDS 3.1003]
ATGACTAGTATTGGCTTAAATATTACAAGCTTTGAACTGGCCTTACTCTTTATGCTCCTCTTTGTTGCTTTCTATTTCAT
TTTTATAGCTTATCGTGATTATCAACAGGTCAAAAATATCCGAAAGTTGACTAAGAGAGTCAAATCCCTTATGGCAGGTA
ATTATAATGAAAAATTATACATAAAGGGAAATTCAGAGCTTTTAGAGCTAGCTAATAGCTTGAATGATTTGTCGGACGTC
TTTCGTTTGACACATGAAAATCTAATTCAGGAAAAAAACCGCTTATCATCTGTCCTTTCGTACATGAGTGACGGGGTTAT
TGCGACCAATCGCCTTGGTCAGATTACTATGATTAATAGTACTGCCCAACGTTTGTTGAATTTAGATCGCGAAACTGCGA
CTCAGATGTCTATTTTGGATATATTAGATGGTGAGAATCCCTATACCTATAGTGAATTGTTGTCTAAGACACCCGAAATC
CATCTGTCGCGTCGAGATGCTAACGATGAATTTGTGACGCTACGTGTTAATTTTGCATTAATTCGTAAGGAATCTGGTTT
TATTTCAGGTCTGGTAGCCGTTCTTCATGATGCCACTGAGCAGGAAAAAGAAGAGCGCGAACGCCGTCTCTTCGTATCAA
ATGTTAGTCACGAATTGCGGACGCCTTTAACTTCTGTGAAATCCTATCTTGAAGCGCTTGATGATGGTGCTCTCAACGAA
GAGATTGCTCCAAACTTTATCAAAGTTTCTTTAGATGAAACCAACCGCATGATGCGTATGATTTCTGACCTCTTGGCATT
ATCTCGAATTGACAATAAAAGCACACAGCTTAATGTTGAAATGACAAACTTTACAGCCTTTATGACCTATATCTTGAATC
GGTTTGGTCAAATTAAGAGTCAAGAAACTAATCCAGGTAAGTCTTATGAAATCATTCGAGATTACCCAGTAAACTCTATT
TGGGTGGAAATTGATACTGATAAGATGACCCAGGTCATAGATAATATACTTAATAATGCCATCAAGTATTCTCCTGATGG
TGGGAAAATTACAGTATCTATGAAAACGACAGACACTCAGTTGATTGTTTCTATTTCTGACCAAGGTTTAGGAATTCCTA
AAAAAGATTTACCTCTGATTTTTGACCGTTTTTACCGTGTTGATAAGGCCAGAAGTCGTGCTCAGGGTGGAACAGGACTT
GGCTTATCCATTGCAAAAGAAATTGTTAAACAACATAATGGCTTCATTTGGGCTAAGAGTGAGTATGGTAAGGGATCAAC
TTTTACAATTGTGCTTCCATATGACCAGGACGCAATGATGGTCGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

HAMP domain (HAMP)

(37-79)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

PAS fold (PAS)

(94-197)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.396

92.825

0.691
  micB Streptococcus pneumoniae Cp1015

66.514

97.758

0.65

Multiple sequence alignment