Detailed information NTG0193328

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: BEN15_RS08790
• Genome accession: NZ_CP016877
• Coordinates: 1665197..1665904 (-)
• Length: 235 a.a.
• NCBI ID: WP_011226084.1
• Uniprot ID: A0A060BQ44
• Organism: Streptococcus thermophilus strain KLDS 3.1003
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1660197..1670904

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BEN15_RS08765 (BEN15_08760)	yidA	1660548..1661357 (+)	810	WP_011226081.1	sugar-phosphatase	-
BEN15_RS08770 (BEN15_08765)	-	1661359..1662573 (+)	1215	WP_065973253.1	aminoacyltransferase	-
BEN15_RS08775 (BEN15_08770)	-	1662625..1662986 (-)	362	Protein_1648	YbaN family protein	-
BEN15_RS08780 (BEN15_08775)	vicX	1663046..1663858 (-)	813	WP_011681204.1	MBL fold metallo-hydrolase	Regulator
BEN15_RS08785 (BEN15_08780)	vicK	1663864..1665204 (-)	1341	WP_065973254.1	cell wall metabolism sensor histidine kinase VicK	Regulator
BEN15_RS08790 (BEN15_08785)	vicR	1665197..1665904 (-)	708	WP_011226084.1	response regulator YycF	Regulator
BEN15_RS08795 (BEN15_08790)	-	1666431..1667198 (+)	768	WP_065973255.1	amino acid ABC transporter ATP-binding protein	-
BEN15_RS08800 (BEN15_08795)	-	1667210..1668043 (+)	834	WP_002953142.1	transporter substrate-binding domain-containing protein	-
BEN15_RS08805 (BEN15_08800)	-	1668061..1668759 (+)	699	WP_065973256.1	amino acid ABC transporter permease	-
BEN15_RS08810 (BEN15_08805)	-	1668771..1669421 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
BEN15_RS08815 (BEN15_08810)	endA	1669493..1670374 (-)	882	WP_065973257.1	DNA/RNA non-specific endonuclease	Machinery gene
BEN15_RS08820 (BEN15_08815)	-	1670436..1670624 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27073.01 Da
• Isoelectric Point: 5.0130

>NTDB_id=193328 BEN15_RS08790 WP_011226084.1 1665197..1665904(-) (vicR) [Streptococcus thermophilus strain KLDS 3.1003]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=193328 BEN15_RS08790 WP_011226084.1 1665197..1665904(-) (vicR) [Streptococcus thermophilus strain KLDS 3.1003]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAGCAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACGGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGATTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCATTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

3D structure

• AlphaFold DB: A0A060BQ44

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.258	99.149	0.796
covR	Streptococcus salivarius strain HSISS4	45.299	99.574	0.451
covR	Lactococcus lactis subsp. lactis strain DGCC12653	45.887	98.298	0.451
scnR	Streptococcus mutans UA159	38.559	100	0.387