Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   CA924_RS04510 Genome accession   NZ_CP021281
Coordinates   971253..971570 (+) Length   105 a.a.
NCBI ID   WP_010946546.1    Uniprot ID   Q5ZXC2
Organism   Legionella pneumophila subsp. pneumophila strain Flint     
Function   dsDNA binding (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 966253..976570
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CA924_RS04490 - 966405..967844 (+) 1440 WP_010946542.1 cation:proton antiporter -
  CA924_RS04495 nadC 967841..968683 (+) 843 WP_010946543.1 carboxylating nicotinate-nucleotide diphosphorylase -
  CA924_RS04500 - 968680..969771 (+) 1092 WP_010946544.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -
  CA924_RS04505 - 969746..971161 (+) 1416 WP_010946545.1 M20 family metallopeptidase -
  CA924_RS04510 comEA 971253..971570 (+) 318 WP_010946546.1 helix-hairpin-helix domain-containing protein Machinery gene
  CA924_RS04515 - 971766..972803 (+) 1038 WP_011213320.1 rod shape-determining protein -
  CA924_RS04520 mreC 972781..973689 (+) 909 WP_010946548.1 rod shape-determining protein MreC -
  CA924_RS04525 mreD 973686..974165 (+) 480 WP_010946549.1 rod shape-determining protein MreD -
  CA924_RS04530 - 974101..974703 (-) 603 WP_011213321.1 pseudouridine synthase -
  CA924_RS04535 - 974964..975662 (+) 699 WP_010946551.1 hypothetical protein -

Sequence

Protein


Download         Length: 105 a.a.        Molecular weight: 11773.78 Da        Isoelectric Point: 10.5233

>NTDB_id=192209 CA924_RS04510 WP_010946546.1 971253..971570(+) (comEA) [Legionella pneumophila subsp. pneumophila strain Flint]
MKARLIAILLSFIVIPFSSQAENEPQKTPAKQVLVKGKINLNTADVYSLTGSFKGIGKKRAEAIIAYRENHQGFKSLEEL
AEVKGIGQRFVDKNREKLKEIFVIN

Nucleotide


Download         Length: 318 bp        

>NTDB_id=192209 CA924_RS04510 WP_010946546.1 971253..971570(+) (comEA) [Legionella pneumophila subsp. pneumophila strain Flint]
ATGAAAGCAAGACTCATTGCTATTTTATTGTCATTTATTGTTATCCCTTTCTCTTCTCAAGCTGAGAACGAGCCTCAAAA
AACTCCAGCTAAACAAGTCCTTGTTAAGGGCAAGATTAATCTTAATACAGCGGATGTGTATTCTTTAACAGGCTCTTTTA
AAGGGATAGGAAAAAAACGGGCTGAAGCTATTATTGCTTATAGAGAGAATCATCAAGGGTTTAAATCTCTGGAAGAGCTT
GCGGAAGTCAAGGGTATAGGGCAGCGTTTTGTAGATAAAAATAGAGAAAAACTGAAAGAAATTTTCGTTATTAATTAA

Domains

Predicted by InterProScan.

Helix-hairpin-helix motif (HHH_3)

(37-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5ZXC2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Legionella pneumophila str. Paris

100

100

1
  comEA Legionella pneumophila strain ERS1305867

100

100

1
  comE1/comEA Haemophilus influenzae Rd KW20

35.455

100

0.371
  comEA Staphylococcus aureus N315

38.384

94.286

0.362
  comEA Staphylococcus aureus MW2

38.384

94.286

0.362