Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   CA920_RS06385 Genome accession   NZ_CP021269
Coordinates   1384305..1384982 (-) Length   225 a.a.
NCBI ID   WP_011213604.1    Uniprot ID   -
Organism   Legionella pneumophila subsp. pneumophila strain Bellingham     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1379305..1389982
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CA920_RS06360 - 1380619..1381362 (+) 744 WP_011213598.1 YebC/PmpR family DNA-binding transcriptional regulator -
  CA920_RS06365 ruvC 1381362..1381886 (+) 525 WP_027220718.1 crossover junction endodeoxyribonuclease RuvC -
  CA920_RS06370 ruvA 1381883..1382482 (+) 600 WP_011213600.1 Holliday junction branch migration protein RuvA -
  CA920_RS06375 - 1382532..1382852 (+) 321 WP_027220717.1 hypothetical protein -
  CA920_RS06380 - 1382893..1384308 (-) 1416 WP_010947022.1 ATP-binding protein -
  CA920_RS06385 ciaR 1384305..1384982 (-) 678 WP_011213604.1 response regulator Regulator
  CA920_RS06390 - 1385043..1385588 (-) 546 WP_011215337.1 septation protein A -
  CA920_RS06395 - 1385825..1387264 (-) 1440 WP_106202082.1 LysM peptidoglycan-binding domain-containing protein -
  CA920_RS06405 gloB 1387378..1388142 (-) 765 WP_011215339.1 hydroxyacylglutathione hydrolase -
  CA920_RS06410 rlmJ 1388146..1388994 (-) 849 WP_027220714.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
  CA920_RS06415 - 1389282..1389491 (+) 210 WP_011213609.1 hypothetical protein -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25151.74 Da        Isoelectric Point: 4.9981

>NTDB_id=192009 CA920_RS06385 WP_011213604.1 1384305..1384982(-) (ciaR) [Legionella pneumophila subsp. pneumophila strain Bellingham]
MRLLLVEDDELLGDAVKAGLTQFGYVVDWLKDGEAARAALKSESFELIILDLGLPKLSGLSLLQNIRHDGNSTPVIILTA
RESIEDRVKGLDSGADDYLIKPFDLNELSARIRALVRRSQGRADSVLQYKNITLDPAAHSVFVDDVLVNVPRREFALLQK
LLENSGQVLSREQLMQSIYGWEEDVDSNALEVHIHNLRKKLNANFIRTIRGVGYMAEKNDSVLLS

Nucleotide


Download         Length: 678 bp        

>NTDB_id=192009 CA920_RS06385 WP_011213604.1 1384305..1384982(-) (ciaR) [Legionella pneumophila subsp. pneumophila strain Bellingham]
ATGAGATTATTACTTGTTGAAGACGATGAACTGCTTGGCGATGCAGTAAAAGCCGGACTGACACAATTTGGTTATGTTGT
TGACTGGCTAAAAGATGGCGAAGCTGCTCGGGCGGCTCTCAAATCAGAGTCTTTTGAATTAATTATTCTTGACTTGGGAT
TACCTAAATTATCCGGTTTATCATTATTGCAAAACATCAGACATGATGGAAATAGCACACCTGTGATTATTCTTACAGCT
CGAGAATCAATAGAAGATCGGGTGAAAGGCTTAGATAGCGGTGCTGACGATTATCTTATTAAACCTTTTGATTTAAACGA
ATTAAGTGCAAGGATTAGAGCATTGGTAAGACGCTCTCAGGGCAGAGCTGATTCCGTGTTGCAATATAAAAATATTACCC
TCGATCCTGCTGCTCATTCTGTATTCGTGGATGATGTACTCGTCAATGTTCCAAGAAGAGAATTTGCTCTATTGCAGAAA
TTACTTGAAAACAGTGGACAGGTTTTATCTCGAGAACAATTAATGCAGAGTATTTATGGCTGGGAAGAAGACGTGGACAG
TAATGCTCTCGAAGTTCATATCCATAATTTACGTAAAAAACTTAACGCAAACTTTATCCGCACTATACGTGGTGTAGGAT
ATATGGCTGAAAAAAATGACAGTGTACTTCTATCGTGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(148-215)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.356

97.333

0.373
  ciaR Streptococcus pneumoniae D39

38.356

97.333

0.373
  ciaR Streptococcus pneumoniae R6

38.356

97.333

0.373
  ciaR Streptococcus pneumoniae TIGR4

38.356

97.333

0.373
  ciaR Streptococcus mutans UA159

37.9

97.333

0.369
  micA Streptococcus pneumoniae Cp1015

35.345

100

0.364