Detailed information NTG0190452

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: CAC01_RS21755
• Genome accession: NZ_CP021118
• Coordinates: 5114260..5115546 (+)
• Length: 428 a.a.
• NCBI ID: WP_007827092.1
• Uniprot ID: A0ABD5DYM9
• Organism: Streptomyces sp. CLI2509 strain CLI2905
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 5109260..5120546

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CAC01_RS21740 (CAC01_21660)	tig	5110925..5112313 (+)	1389	WP_009065295.1	trigger factor	-
CAC01_RS21745 (CAC01_21665)	clpP	5112671..5113276 (+)	606	WP_010271700.1	ATP-dependent Clp protease proteolytic subunit	Regulator
CAC01_RS21750 (CAC01_21670)	clpP	5113394..5114065 (+)	672	WP_007827091.1	ATP-dependent Clp protease proteolytic subunit	Regulator
CAC01_RS21755 (CAC01_21675)	clpX	5114260..5115546 (+)	1287	WP_007827092.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
CAC01_RS21760 (CAC01_21680)	-	5115630..5116658 (-)	1029	WP_095683102.1	hypothetical protein	-
CAC01_RS21765 (CAC01_21685)	-	5116858..5119479 (+)	2622	WP_095683103.1	valine--tRNA ligase	-
CAC01_RS21770 (CAC01_21690)	-	5119692..5120240 (-)	549	WP_007827097.1	hypothetical protein	-

Sequence

Protein

• Length: 428 a.a.
• Molecular weight: 46881.63 Da
• Isoelectric Point: 5.0184

>NTDB_id=190452 CAC01_RS21755 WP_007827092.1 5114260..5115546(+) (clpX) [Streptomyces sp. CLI2509 strain CLI2905]
MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELAETSEVRWEELPKPREIYEFLEGYVVGQEP
AKKALSVAVYNHYKRVQAGENGGPTGRDDAIELAKSNILLLGPTGSGKTHLAQTLARMLNVPFAIADATALTEAGYVGED
VENILLKLIQAADYDVKKAETGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPHQEFIQ
IDTTNVLFIVGGAFSGLERIIEARAGAKGIGFGATIRSKREIESSDHLREVMPEDLVKFGMIPEFIGRLPVVTSVHSLDR
EALLRILVEPRHALVKQYQRLFELDGVELEFEHEALEAIADQAILRQTGARGLRAIMEEVLQPVMYEVPSRQDVGRVVIT
ADVVRSNVNPTLIPREARGRGAGEQKSA

Nucleotide

• Length: 1287 bp

>NTDB_id=190452 CAC01_RS21755 WP_007827092.1 5114260..5115546(+) (clpX) [Streptomyces sp. CLI2509 strain CLI2905]
GTGGCACGCATCGGTGACGGCGGCGACCTGCTCAAGTGCTCGTTCTGCGGGAAGAGCCAGAAGCAGGTAAAGAAGCTCAT
CGCAGGTCCCGGTGTGTACATCTGCGACGAGTGCATCGATCTCTGCAACGAGATCATCGAGGAGGAACTCGCCGAGACCT
CGGAGGTGCGCTGGGAGGAACTGCCCAAGCCCCGCGAGATCTACGAGTTCCTGGAGGGGTACGTCGTCGGCCAGGAGCCG
GCGAAGAAGGCCCTCTCGGTCGCGGTCTACAACCACTACAAGCGCGTCCAGGCCGGTGAGAACGGCGGGCCCACGGGCCG
GGACGACGCGATCGAACTGGCCAAGTCCAACATCCTGTTGCTCGGCCCCACCGGCTCCGGCAAGACCCACCTCGCCCAGA
CCCTCGCCCGGATGCTCAACGTCCCGTTCGCCATCGCGGACGCGACCGCGCTCACCGAGGCCGGCTACGTCGGCGAGGAC
GTCGAGAACATCCTCCTCAAGCTCATCCAGGCGGCCGACTACGACGTCAAGAAGGCCGAGACCGGGATCATCTACATCGA
CGAGATCGACAAGGTCGCCCGCAAGAGCGAGAACCCGTCGATCACCCGCGACGTGAGCGGCGAGGGCGTGCAGCAGGCGC
TCCTGAAGATCCTGGAGGGCACCACGGCCTCCGTGCCCCCGCAGGGCGGACGCAAGCACCCGCACCAGGAGTTCATCCAG
ATCGACACGACGAACGTCCTGTTCATCGTGGGCGGCGCCTTCTCCGGTCTGGAGCGCATCATCGAGGCCCGCGCGGGCGC
CAAGGGCATCGGCTTCGGCGCCACGATCCGCTCCAAGCGCGAGATCGAGTCGAGCGACCACCTGCGCGAGGTCATGCCCG
AGGACCTCGTGAAGTTCGGGATGATCCCCGAGTTCATCGGCCGCCTGCCCGTCGTCACCTCGGTGCACAGCCTCGACCGC
GAAGCCCTCCTGCGCATCCTCGTCGAGCCGCGCCACGCGCTCGTCAAGCAGTACCAGCGCCTCTTCGAACTCGACGGCGT
GGAGCTGGAGTTCGAGCACGAGGCGCTGGAGGCCATCGCCGACCAGGCGATCCTGCGCCAGACCGGCGCCCGTGGCCTGC
GCGCCATCATGGAGGAGGTCCTCCAGCCGGTCATGTACGAGGTGCCCTCGCGCCAGGACGTCGGCCGCGTCGTCATCACC
GCCGACGTCGTCCGCTCCAACGTCAACCCGACCCTCATCCCGCGCGAGGCGCGCGGCCGGGGCGCGGGCGAGCAGAAGTC
GGCCTGA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (115-311)

• ClpX C4-type zinc finger (zf-C4_ClpX) (11-48)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (318-394)

3D structure

• AlphaFold DB: A0ABD5DYM9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	63.5	93.458	0.593
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	53.641	96.262	0.516