Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilE   Type   Machinery gene
Locus tag   A6L48_RS00875 Genome accession   NZ_CP016654
Coordinates   162983..163498 (+) Length   171 a.a.
NCBI ID   WP_065821520.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M22811     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 157983..168498
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6L48_RS15660 - 158181..158267 (+) 87 Protein_153 DUF2061 domain-containing protein -
  A6L48_RS00840 (A6L48_00840) - 158345..158674 (+) 330 WP_065821516.1 FKBP-type peptidyl-prolyl cis-trans isomerase -
  A6L48_RS15360 - 158703..158912 (+) 210 Protein_155 pilin -
  A6L48_RS15730 (A6L48_00850) - 159117..159581 (+) 465 Protein_156 pilin -
  A6L48_RS15370 - 159640..159951 (+) 312 Protein_157 pilin -
  A6L48_RS15230 - 159970..160335 (+) 366 Protein_158 pilin -
  A6L48_RS00860 (A6L48_00860) - 160334..160714 (+) 381 Protein_159 pilin -
  A6L48_RS00865 (A6L48_00865) - 160922..161272 (+) 351 Protein_160 pilin -
  A6L48_RS00870 (A6L48_00870) - 161811..162134 (+) 324 Protein_161 pilin -
  A6L48_RS00875 (A6L48_00875) pilE 162983..163498 (+) 516 WP_065821520.1 pilin Machinery gene
  A6L48_RS00880 (A6L48_00880) lpxC 164477..165400 (+) 924 WP_002216134.1 UDP-3-O-acyl-N-acetylglucosamine deacetylase -
  A6L48_RS00890 (A6L48_00890) gnd 166751..168199 (+) 1449 WP_002236275.1 decarboxylating NADP(+)-dependent phosphogluconate dehydrogenase -

Sequence

Protein


Download         Length: 171 a.a.        Molecular weight: 18218.57 Da        Isoelectric Point: 8.4549

>NTDB_id=190391 A6L48_RS00875 WP_065821520.1 162983..163498(+) (pilE) [Neisseria meningitidis strain M22811]
MNTLQKGFTLIELMIVIAIVGILAAVALPAYQDYTARAQVSEAILLAEGQKSAVTEYYLNHGKWPDDNSNAGVASSSTIK
GKYVQSVTVANGVITAQMASSNVNKEIKDKKLSLWAKRQDGSVKWFCGQPVQRANANGANNDEVTAATGKGTDKIDTKHL
PSTCRDASDAS

Nucleotide


Download         Length: 516 bp        

>NTDB_id=190391 A6L48_RS00875 WP_065821520.1 162983..163498(+) (pilE) [Neisseria meningitidis strain M22811]
ATGAACACCCTTCAAAAAGGTTTTACCCTTATCGAGCTGATGATTGTGATTGCCATCGTCGGCATTTTGGCGGCAGTCGC
CCTTCCTGCTTATCAAGACTACACAGCCCGCGCACAAGTTTCCGAAGCCATTCTTTTGGCCGAAGGTCAAAAATCAGCCG
TCACAGAGTATTACCTGAATCACGGCAAATGGCCTGACGACAACAGTAATGCCGGCGTGGCATCTTCTTCAACAATCAAA
GGCAAATATGTTCAAAGCGTTACAGTCGCAAACGGCGTCATTACCGCCCAAATGGCTTCAAGCAACGTAAACAAAGAAAT
CAAAGACAAAAAACTCTCCCTGTGGGCCAAGCGTCAAGACGGTTCGGTAAAATGGTTCTGCGGACAGCCGGTTCAGCGCG
CCAACGCCAACGGCGCCAACAACGACGAAGTCACCGCCGCCACCGGCAAGGGCACCGACAAAATCGACACCAAGCACCTG
CCGTCAACCTGCCGCGACGCAAGTGATGCCAGCTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(5-28)

Pilin (bacterial filament) (Pilin)

(36-165)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilE Neisseria gonorrhoeae strain FA1090

81.287

100

0.813
  pilE Neisseria gonorrhoeae MS11

77.326

100

0.778
  pilA/pilA1 Eikenella corrodens VA1

36.932

100

0.38
  comP Acinetobacter baylyi ADP1

36.628

100

0.368

Multiple sequence alignment