Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   B9W17_RS04185 Genome accession   NZ_CP020933
Coordinates   898600..899232 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain HB-Coli0     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 893600..904232
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B9W17_RS04160 (B9W17_04435) yhfG 893732..893899 (+) 168 WP_000736860.1 YhfG family protein -
  B9W17_RS04165 (B9W17_04440) fic 893889..894491 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  B9W17_RS04170 (B9W17_04445) pabA 894523..895086 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  B9W17_RS04175 (B9W17_04450) argD 895172..896392 (+) 1221 WP_000963797.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  B9W17_RS04180 (B9W17_04455) yhfK 896459..898549 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  B9W17_RS04185 (B9W17_04460) crp 898600..899232 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  B9W17_RS04190 (B9W17_04470) yhfA 899534..899938 (+) 405 WP_001148908.1 OsmC family protein -
  B9W17_RS04195 (B9W17_04475) prkB 899993..900862 (-) 870 WP_001274680.1 phosphoribulokinase -
  B9W17_RS04200 (B9W17_04480) yheU 900916..901134 (-) 219 WP_000907085.1 YheU family protein -
  B9W17_RS04205 (B9W17_04485) yheT 901128..902150 (-) 1023 WP_000057405.1 hydrolase -
  B9W17_RS04210 (B9W17_04490) yheS 902150..904063 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=189916 B9W17_RS04185 WP_000242755.1 898600..899232(-) (crp) [Escherichia coli strain HB-Coli0]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=189916 B9W17_RS04185 WP_000242755.1 898600..899232(-) (crp) [Escherichia coli strain HB-Coli0]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment