Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   A6L21_RS01560 Genome accession   NZ_CP016644
Coordinates   282000..285119 (-) Length   1039 a.a.
NCBI ID   WP_079883562.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M07162     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 277000..290119
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6L21_RS13430 - 277539..277706 (-) 168 WP_153312129.1 hypothetical protein -
  A6L21_RS01530 (A6L21_01530) - 277710..278099 (-) 390 WP_002221514.1 endonuclease domain-containing protein -
  A6L21_RS01545 (A6L21_01545) - 278679..278816 (-) 138 WP_002214606.1 VOC family protein -
  A6L21_RS01550 (A6L21_01550) carA 278862..279995 (-) 1134 WP_002245197.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  A6L21_RS01560 (A6L21_01560) pilC 282000..285119 (-) 3120 WP_079883562.1 PilC family type IV pilus tip adhesin Machinery gene
  A6L21_RS01565 (A6L21_01565) apbC 286073..287152 (-) 1080 WP_002248538.1 iron-sulfur cluster carrier protein ApbC -
  A6L21_RS01575 (A6L21_01575) - 287517..288026 (+) 510 WP_002224078.1 protein disulfide oxidoreductase -
  A6L21_RS01585 (A6L21_01585) nadR 288369..288809 (+) 441 WP_002221507.1 MarR family adhesin repressor NadR -
  A6L21_RS01590 (A6L21_01590) hpaC 288924..289424 (+) 501 WP_002248346.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -

Sequence

Protein


Download         Length: 1039 a.a.        Molecular weight: 113598.42 Da        Isoelectric Point: 9.8073

>NTDB_id=189916 A6L21_RS01560 WP_079883562.1 282000..285119(-) (pilC) [Neisseria meningitidis strain M07162]
MNKTLKRRVFRHTALYAAILMFSHTGGGGAQAETHNYAIVMNEQNQLKVKQKDSYSTLREKDRERKFIYNKGWQGGGSVF
FDNTDTLVSRQSGTAVFGTATYLPPYGKVSGFDANALKERNNAVDWIHTTRAGLAGYAYTNVICRSHQCPQLVYKTRFSF
DNPDLAKRGGGLDRHTEPSRDNSLIYKLKDHPWLGVSFNLGSENTVKNSQSSSRLISSFSEDNNNQTIVSTTENHPISLG
DGQREHTAVAYYLNAKLHLLDKKGIKDITGKTVRLGVLKPSIDVKTQRTGLGGLLGFHAKWDIKDTGQIPVELGLPQIKA
GRCINKPNPNPKAQALSPALTAPALWFGPVQNGKVQMYSASVSTYPDSSSSQIFLQNLSRKDDTSKPGRYSLKPLSTSEI
KSKEPTFTGRQTVIRLDGGVQQIKLQGNEVTSFNVNNGNNTFGIVKDLGVDPDASEWKKVLLPWTVRASNDDNQFKTINQ
QLNQQKIQYSQRYRIRDNGNRDLGDIVNSPIVAVGEYLATSANDGMVHIFKQSGGDKRSYNLKLSYIPGTMPRQYFDNDT
SALKDSTLAKELRTFAEKGYVGDRYGVDGGFVLRRITDDQDKQKHFFMFGAMGLGGRGAYALDLTKADSNNPTAVSLFDV
KNGNNGKNSNNSNNSVQLGYTVGTPQIGKTHNGKYAAFLASGYATKDINNGDNKTALYVYDLESNGNLIKKIEVPGGKGG
LSSPTLVDKDLDGTVDIAYAGDRGGSMYRFDLSGNNPTSWSARAIFSGNKPITSAPAISQLKDKRVVIFGTGSDLSEEDV
DSKEIQHVYGIFDNDTDTGTAQDGQGKGLLEQKLEKDKDGKTLFLSDYKRSDGSGDKGWVVKLEAGQRVTVKPTVVLRTA
FVTIHKYTGNDKCGAETAILGINTADGGKLTKKSARPIVPADNTAVAQYSGHKQTAKGKSIPIGCMEKNNGIVCPNGYVY
DKPVNVRYLDEKKTDGFSTTADGDAGGSGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLDITGPTCGMKRISWREVFY

Nucleotide


Download         Length: 3120 bp        

>NTDB_id=189916 A6L21_RS01560 WP_079883562.1 282000..285119(-) (pilC) [Neisseria meningitidis strain M07162]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGGGG
GGGGGGGGCGCAGGCGGAAACCCATAACTACGCTATTGTCATGAACGAACAAAATCAGCTGAAGGTAAAGCAGAAGGATT
CATATTCAACCTTAAGGGAAAAAGACAGGGAACGCAAATTTATCTATAATAAAGGCTGGCAGGGTGGAGGCTCTGTCTTT
TTCGACAATACCGATACCCTTGTTTCCCGACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCCCTACGG
CAAGGTTTCCGGTTTTGATGCCAACGCTCTGAAAGAGCGCAACAATGCCGTCGATTGGATTCATACCACCCGGGCCGGGC
TGGCAGGCTACGCCTACACCAACGTCATATGCAGAAGCCACCAATGCCCCCAACTTGTCTATAAAACCCGATTTTCCTTC
GATAATCCCGACTTGGCAAAAAGAGGAGGCGGGCTGGATAGGCACACAGAGCCAAGCCGCGACAATTCGCTCATTTACAA
ATTGAAGGATCATCCATGGTTGGGCGTATCTTTCAATTTGGGCAGCGAGAATACCGTCAAAAATAGCCAATCATCCAGCA
GATTGATATCTTCTTTTAGTGAAGACAATAATAATCAAACCATCGTCTCTACGACAGAAAACCACCCTATTTCCCTTGGC
GACGGGCAGCGCGAACATACCGCCGTGGCCTATTATCTGAACGCCAAACTGCACCTGCTGGATAAAAAAGGGATTAAAGA
TATCACCGGCAAAACAGTGCGGTTGGGTGTCTTGAAGCCGAGCATCGATGTGAAGACACAAAGGACGGGGCTTGGCGGCT
TGCTAGGTTTTCATGCTAAGTGGGACATTAAAGATACCGGGCAGATTCCGGTCGAGCTCGGCCTGCCGCAAATCAAAGCA
GGCCGCTGCATCAACAAACCGAACCCCAATCCCAAAGCCCAAGCCCTTTCGCCGGCACTGACTGCCCCCGCGCTGTGGTT
CGGACCTGTGCAAAATGGCAAGGTGCAGATGTATTCCGCTTCGGTTTCCACCTACCCCGACAGTTCGAGCAGCCAAATTT
TCCTGCAAAACCTTTCCCGCAAGGATGACACAAGCAAACCGGGCCGCTATTCCCTCAAACCCTTGAGTACGTCGGAGATT
AAAAGTAAAGAGCCGACTTTCACAGGGCGGCAAACCGTCATCCGATTGGATGGCGGCGTACAGCAGATTAAACTTCAAGG
CAATGAGGTCACTAGTTTTAATGTAAACAACGGCAACAACACTTTCGGCATTGTTAAGGACTTGGGCGTCGATCCTGATG
CCAGCGAGTGGAAAAAAGTGCTGCTGCCTTGGACGGTTCGTGCTTCCAATGATGACAATCAATTTAAAACAATTAACCAA
CAACTTAACCAACAAAAAATCCAATACAGCCAAAGATACCGCATCCGCGACAACGGCAATCGCGATTTGGGCGACATCGT
CAACAGCCCCATCGTGGCGGTCGGCGAGTATTTGGCTACTTCCGCCAACGACGGGATGGTGCATATCTTCAAACAAAGCG
GCGGGGACAAGCGCAGCTACAATCTGAAGCTCAGCTACATCCCCGGCACGATGCCGCGCCAATATTTTGATAACGACACT
TCCGCTCTCAAAGACTCCACCCTCGCCAAAGAGCTGCGCACCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGT
GGACGGCGGCTTTGTCTTGCGCCGCATTACAGATGACCAAGACAAGCAAAAACATTTCTTTATGTTTGGTGCGATGGGCC
TGGGCGGCAGAGGCGCGTATGCCTTGGATTTGACCAAAGCCGACAGCAATAACCCGACCGCCGTTTCCCTGTTTGATGTC
AAAAATGGCAATAATGGCAAGAATAGCAATAATAGCAATAATAGCGTGCAATTAGGCTACACCGTCGGCACGCCGCAAAT
CGGCAAAACCCACAACGGCAAATACGCCGCCTTCCTCGCCTCCGGTTATGCGACTAAAGACATTAACAACGGCGACAATA
AAACCGCGCTGTATGTGTATGATTTGGAAAGCAACGGCAATTTGATTAAAAAAATCGAAGTACCCGGTGGCAAGGGCGGG
CTTTCGTCCCCCACGCTGGTGGATAAAGATTTGGACGGCACGGTTGATATCGCCTATGCCGGCGATCGCGGCGGCAGTAT
GTACCGCTTTGATTTAAGCGGCAACAACCCGACCAGTTGGTCTGCACGCGCCATTTTCAGCGGCAACAAACCGATTACTT
CCGCGCCCGCCATTTCCCAACTGAAAGACAAACGCGTGGTTATCTTCGGCACGGGCAGCGATTTGAGTGAAGAGGATGTG
GACAGCAAAGAAATCCAACACGTTTACGGTATTTTTGACAATGACACAGACACGGGTACGGCGCAAGACGGGCAGGGCAA
AGGGCTGCTCGAGCAAAAGCTGGAAAAAGACAAAGACGGCAAAACGCTGTTTTTAAGCGACTACAAAAGGTCTGACGGCT
CGGGCGACAAGGGCTGGGTAGTGAAATTGGAAGCCGGACAGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCC
TTTGTAACCATCCATAAATATACGGGTAATGACAAATGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGG
CGGCAAGCTGACCAAGAAAAGCGCGCGCCCGATTGTGCCGGCCGACAATACGGCTGTCGCGCAATATTCCGGTCATAAGC
AAACCGCCAAAGGCAAATCCATCCCTATAGGTTGTATGGAAAAAAACAATGGAATCGTCTGCCCGAACGGATATGTTTAC
GACAAACCGGTTAATGTGCGTTATCTGGATGAAAAGAAAACAGACGGATTTTCAACAACGGCAGACGGCGATGCGGGCGG
CAGCGGAACATTCAAAGAGGGTAAAAAACCCGCCCGCAATAACCGGTGCTTCTCCGGAAAAGGTGTGCGCACCCTGCTGA
TGAACGATTTGGACAGCTTGGACATTACCGGCCCGACGTGCGGTATGAAACGAATCAGCTGGCGTGAAGTCTTCTACTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(503-846)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

76.879

100

0.778

Multiple sequence alignment