Detailed information NTG0189647

Bioinformatically predicted

Overview

• Name: pilC
• Type: Machinery gene
• Locus tag: A6B42_RS05605
• Genome accession: NZ_CP016607
• Coordinates: 1149893..1151089 (-)
• Length: 398 a.a.
• NCBI ID: WP_178217952.1
• Uniprot ID: -
• Organism: Mannheimia varigena strain F222
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1144893..1156089

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6B42_RS05580 (A6B42_05580)	lptE	1146848..1147336 (+)	489	WP_178217945.1	LPS assembly lipoprotein LptE	-
A6B42_RS05585 (A6B42_05585)	holA	1147376..1148398 (+)	1023	WP_178217947.1	DNA polymerase III subunit delta	-
A6B42_RS05590 (A6B42_05590)	yacG	1148399..1148584 (-)	186	WP_176671236.1	DNA gyrase inhibitor YacG	-
A6B42_RS05595 (A6B42_05595)	coaE	1148566..1149201 (-)	636	WP_178217948.1	dephospho-CoA kinase	-
A6B42_RS05600 (A6B42_05600)	-	1149233..1149889 (-)	657	WP_178217950.1	prepilin peptidase	-
A6B42_RS05605 (A6B42_05605)	pilC	1149893..1151089 (-)	1197	WP_178217952.1	type II secretion system F family protein	Machinery gene
A6B42_RS05610 (A6B42_05610)	-	1151082..1152473 (-)	1392	Protein_1098	GspE/PulE family protein	-
A6B42_RS05615 (A6B42_05615)	pilA	1152494..1152973 (-)	480	WP_025217064.1	prepilin peptidase-dependent pilin	Machinery gene
A6B42_RS05620 (A6B42_05620)	radA	1153153..1154532 (+)	1380	WP_178217954.1	DNA repair protein RadA	-
A6B42_RS05625 (A6B42_05625)	-	1154588..1154821 (-)	234	WP_025217062.1	YgjV family protein	-

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 45670.15 Da
• Isoelectric Point: 9.1625

>NTDB_id=189647 A6B42_RS05605 WP_178217952.1 1149893..1151089(-) (pilC) [Mannheimia varigena strain F222]
MAKIYEFHWKAVDRFQQKRKGRLLSSNREELENRLLTKGYQQIHISRNFVFSQNPKREEISQFLAQLALLVNSAVPLKQA
LVMILQNCRNIELHLWLSELIQLIESGYAFSQSLERLNKFIANQEIQLIKMGEQSGKLGLILTNLAESRLKSDKLAKKVK
KILFYPAIVLFISFSLSIGLLVFIVPQFAELYGTKEQALPLITEILFSLSQCLIEQKNLLFSLFLLAVIFFLFFAKRGNW
AAKLKISVLSKLPVFRQIIEQARIVFFNQNIALMLNAHIPLDVALKSFLSEKSDDPILQKEVEFMLNLLQQGYKFSQGIN
SNVFGLDMPQMIEIVEQSGNVAKMCEHISEMYQQKLDYQIDILSQLLEPMLMLLMGVIVGTIIVGLYLPIFDMGSLVE

Nucleotide

• Length: 1197 bp

>NTDB_id=189647 A6B42_RS05605 WP_178217952.1 1149893..1151089(-) (pilC) [Mannheimia varigena strain F222]
ATGGCTAAAATCTATGAGTTTCATTGGAAGGCGGTAGATCGTTTTCAACAAAAACGTAAGGGCAGATTATTATCTTCAAA
CAGAGAAGAGCTTGAAAATAGATTACTTACTAAAGGTTATCAGCAAATTCACATTAGCCGAAACTTTGTGTTTTCACAAA
ACCCTAAAAGAGAAGAAATTAGTCAATTTCTCGCTCAGCTTGCTTTGTTGGTTAATTCTGCTGTGCCGTTAAAACAAGCC
TTAGTAATGATTTTACAAAACTGTCGAAATATTGAGCTTCATCTATGGCTAAGCGAGCTTATTCAACTCATTGAAAGTGG
TTATGCTTTTTCACAATCATTAGAACGGCTCAATAAATTTATCGCTAACCAAGAAATTCAACTAATTAAAATGGGCGAGC
AGAGCGGAAAACTCGGTTTGATTTTAACCAACTTGGCGGAGAGCAGACTTAAATCGGATAAACTGGCTAAAAAAGTCAAG
AAAATCCTGTTTTATCCAGCAATTGTACTGTTTATCTCATTCTCTCTTTCTATCGGACTTTTGGTATTCATCGTGCCACA
ATTTGCCGAACTTTACGGCACAAAAGAACAAGCCTTACCGCTGATTACTGAGATTTTATTTTCTCTTTCTCAATGTTTGA
TTGAACAGAAGAATCTTTTATTCAGCTTATTTTTACTAGCGGTTATTTTTTTCTTATTTTTTGCAAAAAGAGGGAATTGG
GCAGCGAAATTGAAAATCAGCGTATTGTCTAAGCTCCCTGTTTTTAGACAAATTATAGAGCAAGCTCGCATTGTCTTTTT
TAACCAAAATATTGCGTTGATGTTGAATGCTCATATTCCATTAGATGTCGCATTAAAATCCTTTTTATCTGAAAAAAGTG
ATGACCCTATATTACAAAAAGAAGTTGAGTTTATGCTCAATCTCTTACAACAAGGCTATAAGTTTTCGCAAGGTATCAAC
TCAAATGTGTTTGGCTTAGATATGCCTCAGATGATTGAGATAGTCGAACAGAGTGGTAATGTTGCCAAAATGTGTGAGCA
TATTAGCGAGATGTATCAACAAAAACTGGATTATCAAATTGATATTCTCTCCCAATTATTAGAGCCAATGCTGATGCTAT
TAATGGGCGTAATTGTCGGCACTATTATTGTTGGGCTGTACTTGCCTATTTTCGATATGGGCTCATTGGTGGAGTAG

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (269-389)

• Type II secretion system (T2SS), protein F (T2SSF) (63-186)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilC	Glaesserella parasuis strain SC1401	55.611	100	0.56
pilC	Haemophilus influenzae Rd KW20	42.145	100	0.425
pilC	Haemophilus influenzae 86-028NP	41.147	100	0.415