Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   A6B39_RS01935 Genome accession   NZ_CP016606
Coordinates   354481..355785 (-) Length   434 a.a.
NCBI ID   WP_176669503.1    Uniprot ID   -
Organism   Mannheimia granulomatis strain BJ1680.3     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 349481..360785
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6B39_RS01900 - 349784..350011 (+) 228 WP_176669498.1 hypothetical protein -
  A6B39_RS01905 (A6B39_01860) ruvB 350101..351105 (-) 1005 WP_165889239.1 Holliday junction branch migration DNA helicase RuvB -
  A6B39_RS01910 (A6B39_01865) ruvA 351116..351721 (-) 606 WP_176669499.1 Holliday junction branch migration protein RuvA -
  A6B39_RS01915 (A6B39_01870) - 351834..352460 (-) 627 WP_176669500.1 LysE family transporter -
  A6B39_RS01920 (A6B39_01875) - 352468..352941 (-) 474 WP_176669501.1 phosphatidylglycerophosphatase A -
  A6B39_RS01925 (A6B39_01880) thiL 352947..353927 (-) 981 WP_176669502.1 thiamine-phosphate kinase -
  A6B39_RS01930 (A6B39_01885) nusB 353991..354404 (-) 414 WP_027074137.1 transcription antitermination factor NusB -
  A6B39_RS01935 (A6B39_01890) comE 354481..355785 (-) 1305 WP_176669503.1 type IV pilus secretin PilQ Machinery gene
  A6B39_RS01940 (A6B39_01895) - 355794..356201 (-) 408 WP_176669504.1 hypothetical protein -
  A6B39_RS01945 (A6B39_01900) - 356194..356739 (-) 546 WP_176669505.1 hypothetical protein -
  A6B39_RS01950 (A6B39_01905) - 356743..357261 (-) 519 WP_176669506.1 hypothetical protein -
  A6B39_RS01955 (A6B39_01910) - 357237..357947 (-) 711 WP_176669507.1 competence protein ComA -
  A6B39_RS01960 (A6B39_01915) - 358071..360626 (+) 2556 WP_176669508.1 penicillin-binding protein 1A -

Sequence

Protein


Download         Length: 434 a.a.        Molecular weight: 47978.10 Da        Isoelectric Point: 7.5960

>NTDB_id=189621 A6B39_RS01935 WP_176669503.1 354481..355785(-) (comE) [Mannheimia granulomatis strain BJ1680.3]
MSKILSLLLLIPSLVLANTLSISLKNAPTPAILTYLAEETDKNIVLEDNIDTKTTLRLDNKSIDEILKTISKINKLSLKQ
ENDIAYINKQENKSESMPPIAHLQNNGQIQPLAPPKLITKTIKLYYAKASEIIDSLTKGSGTFLSENGYIHFDERSNSLI
IKDSEKSLRNIEKLVKKLDHPTEQIAIEARIVTISSEHLQELGVRWGMFSSSPDHYKFGGKLEGNGLNNVANNLNVNFPV
ANGASAVLQVASINSRLLDLELSALEQENSVEIIASPRLLTTNKKAASIKQGTEIPYVMYNTKSEATDVEFKEAVLGLEV
TPHLSTQNQILLDLIVTQNSPNSQSGSSGLITIDKQELNTQVFAKHGETIVLGGIFQHLTQKGEDKVPILGSIPFIKRLF
SQTRDKISKRELVIFVTPYILQSSEKTITTSKLK

Nucleotide


Download         Length: 1305 bp        

>NTDB_id=189621 A6B39_RS01935 WP_176669503.1 354481..355785(-) (comE) [Mannheimia granulomatis strain BJ1680.3]
ATGTCTAAAATTCTCTCATTATTATTGCTTATCCCTTCTCTTGTCTTAGCAAATACATTATCTATTTCATTAAAAAATGC
TCCAACACCTGCAATATTGACTTATTTAGCAGAAGAAACCGATAAAAATATTGTATTGGAAGATAATATAGACACTAAAA
CCACCTTACGTTTAGACAATAAATCTATTGATGAAATATTAAAAACAATAAGTAAAATCAATAAGTTATCATTAAAGCAA
GAGAACGATATTGCTTATATCAATAAACAAGAAAATAAGTCAGAAAGTATGCCACCAATCGCTCATTTGCAAAATAACGG
GCAAATTCAACCGCTTGCTCCACCAAAACTTATCACGAAAACGATCAAACTTTATTATGCTAAAGCTTCTGAAATAATAG
ACTCTTTAACTAAAGGCAGTGGTACATTTCTATCGGAAAACGGCTATATTCATTTTGATGAAAGAAGTAATAGTTTGATT
ATTAAAGACAGCGAAAAGTCGTTACGAAATATAGAAAAATTAGTAAAAAAACTCGATCATCCAACTGAGCAAATTGCTAT
AGAGGCCAGAATTGTAACGATTAGCAGCGAACACCTACAAGAGCTTGGTGTACGCTGGGGTATGTTTTCCTCAAGTCCGG
ATCATTATAAATTTGGCGGCAAGCTGGAAGGTAATGGTTTGAACAATGTGGCTAACAATTTAAATGTTAATTTCCCGGTA
GCAAATGGAGCTTCTGCAGTCTTACAAGTTGCCTCAATTAATAGCCGCCTACTAGATTTGGAGCTTTCTGCACTTGAGCA
AGAAAACAGTGTAGAAATTATTGCAAGCCCTCGCCTACTCACTACCAATAAAAAAGCCGCCAGCATCAAACAAGGTACGG
AAATTCCTTATGTGATGTATAACACAAAATCAGAAGCAACTGATGTTGAGTTTAAAGAAGCTGTATTAGGGCTGGAAGTT
ACCCCTCACCTTTCTACGCAAAATCAGATCTTACTGGATCTGATTGTGACTCAAAATTCTCCTAATTCGCAATCCGGCAG
CAGTGGTTTAATTACCATAGATAAACAAGAATTGAATACACAAGTCTTTGCCAAACACGGAGAAACCATTGTTTTAGGTG
GTATTTTCCAACATTTAACCCAAAAAGGAGAGGATAAAGTACCAATTTTAGGCTCAATTCCCTTTATTAAACGGCTGTTT
AGCCAAACCCGAGATAAAATCAGCAAGCGGGAATTAGTCATTTTCGTTACCCCTTATATTTTGCAATCTAGTGAGAAAAC
CATCACCACCTCAAAATTAAAATAG

Domains

Predicted by InterproScan.

Bacterial type II/III secretion system short domain (Secretin_N)

(119-184)

Bacterial type II and III secretion system protein (Secretin)

(264-421)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Glaesserella parasuis strain SC1401

64.775

97.465

0.631
  comE Haemophilus influenzae Rd KW20

52.214

98.848

0.516
  comE Haemophilus influenzae 86-028NP

51.515

98.848

0.509
  pilQ Vibrio campbellii strain DS40M4

38.228

98.848

0.378
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

38.626

97.235

0.376
  pilQ Vibrio cholerae strain A1552

38.626

97.235

0.376

Multiple sequence alignment