Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   A6A11_RS07360 Genome accession   NZ_CP016605
Coordinates   1601700..1603052 (-) Length   450 a.a.
NCBI ID   WP_132023455.1    Uniprot ID   -
Organism   Bisgaardia hudsonensis strain M327/99/2     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1596700..1608052
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6A11_RS07335 (A6A11_07235) - 1596887..1597195 (+) 309 WP_132023445.1 DciA family protein -
  A6A11_RS07340 (A6A11_07240) - 1597387..1598859 (-) 1473 WP_132023447.1 nicotinate phosphoribosyltransferase -
  A6A11_RS07345 (A6A11_07245) - 1598997..1599848 (-) 852 WP_132023449.1 Dam family site-specific DNA-(adenine-N6)-methyltransferase -
  A6A11_RS07350 (A6A11_07250) aroB 1599854..1600942 (-) 1089 WP_132023451.1 3-dehydroquinate synthase -
  A6A11_RS09990 (A6A11_07255) aroK 1600967..1601494 (-) 528 WP_132023453.1 shikimate kinase AroK -
  A6A11_RS07360 (A6A11_07260) comE 1601700..1603052 (-) 1353 WP_132023455.1 type IV pilus secretin PilQ Machinery gene
  A6A11_RS07365 (A6A11_07265) - 1603061..1603459 (-) 399 WP_132023457.1 hypothetical protein -
  A6A11_RS07370 (A6A11_07270) - 1603462..1604004 (-) 543 WP_132023459.1 hypothetical protein -
  A6A11_RS07375 (A6A11_07275) - 1604001..1604513 (-) 513 WP_132023461.1 PilN domain-containing protein -
  A6A11_RS07380 (A6A11_07280) - 1604503..1605327 (-) 825 WP_132023463.1 hypothetical protein -
  A6A11_RS07385 (A6A11_07285) - 1605456..1608029 (+) 2574 WP_132023465.1 penicillin-binding protein 1A -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 49851.45 Da        Isoelectric Point: 9.2830

>NTDB_id=189607 A6A11_RS07360 WP_132023455.1 1601700..1603052(-) (comE) [Bisgaardia hudsonensis strain M327/99/2]
MQKKIIFIIKYSVLFGSLSNLLWADNQFSIRLKQAPMVATLQQLALQQNINLIIDDNLSGSLSLQLQKTNLDKFLRSVAK
SKRLELLKEDNIYYLTEKIYEPLRPTQESLGKSIILSEPELIQSSVKLHYAKASEVIKSLTTGTGSLLSSEGSISFDDRT
NTLLIKDSKQSIKQFKKLVEDLDQPIQQVAIEARIVTMTDQSLRELGVRWGILDSSANNHAITGRLESTGITNLKDQLNI
NFATTTNPAGALALQIAKINGRLLDLELTALEQENAVEIIASPRLITTNKQSASIKQGTELPYVSVNEKSGSQSIEFREA
VLGLDVTPHISKNNTILLDLVISQNAPGNSITYGLGEVVSIDKQEINTQVLAENGETIVLGGVFHDTITKGKDKVPVLGD
ILVIEHLFSKQNEQHQKRELVIFVTPRIVKKNTLIKQGQIVQKVSNILKK

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=189607 A6A11_RS07360 WP_132023455.1 1601700..1603052(-) (comE) [Bisgaardia hudsonensis strain M327/99/2]
ATGCAAAAAAAGATCATATTTATCATAAAATATAGTGTATTGTTTGGTAGTTTATCCAATTTATTATGGGCGGATAATCA
GTTTTCAATTCGATTAAAACAGGCTCCAATGGTTGCAACACTGCAACAGCTTGCGTTACAACAGAATATTAATCTTATTA
TTGATGATAATTTATCTGGTAGTCTTTCATTACAATTACAAAAAACAAATTTGGATAAGTTTTTAAGATCAGTTGCAAAA
AGTAAACGCTTAGAGTTATTGAAAGAAGATAATATTTATTATTTGACTGAGAAAATTTATGAACCTTTGCGCCCAACTCA
AGAGAGCTTGGGGAAGAGTATAATACTTTCTGAACCAGAACTTATTCAATCTAGTGTTAAGTTACATTATGCAAAAGCAT
CGGAAGTGATAAAGTCGCTGACAACGGGAACTGGTTCGTTATTGTCCTCTGAAGGAAGTATTAGTTTTGATGATAGAACA
AATACATTATTGATAAAAGATAGTAAGCAATCAATAAAGCAGTTTAAAAAATTAGTAGAAGATTTGGATCAACCTATTCA
GCAAGTTGCTATTGAAGCAAGAATCGTAACGATGACAGATCAAAGTTTAAGAGAACTTGGGGTCAGATGGGGGATTTTGG
ATTCATCAGCAAATAACCATGCTATCACAGGACGTTTAGAATCTACTGGGATTACAAATTTAAAGGATCAATTAAATATT
AATTTTGCTACCACAACTAATCCAGCAGGCGCTCTAGCCTTACAAATTGCTAAAATTAATGGGCGTTTACTTGATTTAGA
ACTTACTGCACTTGAGCAGGAAAATGCTGTTGAAATTATTGCTAGTCCAAGATTAATTACGACCAATAAACAAAGTGCGA
GTATTAAGCAAGGAACGGAGTTACCCTATGTTTCTGTGAATGAAAAAAGTGGTTCACAATCAATTGAGTTTAGGGAAGCG
GTATTAGGTTTAGATGTTACGCCACATATTTCTAAAAATAATACTATATTACTTGATCTTGTTATTAGCCAGAATGCACC
AGGTAATAGTATTACTTATGGATTAGGTGAAGTGGTTTCTATTGATAAGCAGGAAATTAATACACAAGTTTTAGCGGAAA
ACGGTGAAACTATTGTATTAGGTGGGGTATTTCACGATACGATAACAAAAGGAAAAGATAAGGTTCCTGTACTTGGTGAT
ATTCTAGTGATTGAGCATCTTTTTAGTAAACAAAATGAACAACATCAAAAAAGAGAGTTGGTCATTTTTGTAACACCAAG
AATTGTAAAGAAAAATACGTTAATTAAACAAGGGCAAATTGTTCAGAAAGTATCTAATATTTTGAAAAAATAG

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(270-430)

Bacterial type II/III secretion system short domain (Secretin_N)

(126-188)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae 86-028NP

58.661

96.222

0.564
  comE Haemophilus influenzae Rd KW20

59.198

94.222

0.558
  comE Glaesserella parasuis strain SC1401

50.237

93.778

0.471
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

42.41

92.222

0.391
  pilQ Vibrio cholerae strain A1552

42.41

92.222

0.391
  pilQ Vibrio campbellii strain DS40M4

40.521

93.778

0.38

Multiple sequence alignment