Detailed information NTG0189127

Bioinformatically predicted

Overview

• Name: pilC
• Type: Machinery gene
• Locus tag: BBH51_RS03390
• Genome accession: NZ_CP016553
• Coordinates: 677146..678369 (-)
• Length: 407 a.a.
• NCBI ID: WP_005540455.1
• Uniprot ID: Q8KRY4
• Organism: Aggregatibacter actinomycetemcomitans strain IDH781
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 672146..683369

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BBH51_RS03370 (BBH51_03370)	-	672812..674932 (-)	2121	WP_005539198.1	alpha/beta hydrolase	-
BBH51_RS03375 (BBH51_03375)	-	674955..676082 (-)	1128	WP_005539200.1	DUF4123 domain-containing protein	-
BBH51_RS03380 (BBH51_03380)	-	676112..676291 (-)	180	WP_187374682.1	hypothetical protein	-
BBH51_RS03385 (BBH51_03385)	-	676460..677149 (-)	690	WP_033001430.1	prepilin peptidase	-
BBH51_RS03390 (BBH51_03390)	pilC	677146..678369 (-)	1224	WP_005540455.1	type II secretion system F family protein	Machinery gene
BBH51_RS03395 (BBH51_03395)	pilB	678362..679771 (-)	1410	WP_005540457.1	GspE/PulE family protein	Machinery gene
BBH51_RS03400 (BBH51_03400)	pilA	679798..680250 (-)	453	WP_005550263.1	pilin	Machinery gene
BBH51_RS03405 (BBH51_03405)	ampD	680372..680926 (+)	555	WP_005540460.1	1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD	-
BBH51_RS03410 (BBH51_03410)	nanQ	681400..681870 (-)	471	WP_005540462.1	N-acetylneuraminate anomerase	-

Sequence

Protein

• Length: 407 a.a.
• Molecular weight: 46222.71 Da
• Isoelectric Point: 10.3517

>NTDB_id=189127 BBH51_RS03390 WP_005540455.1 677146..678369(-) (pilC) [Aggregatibacter actinomycetemcomitans strain IDH781]
MTKLKLFQWRGVNRLQQKQKGLIVAETEVMAQQQLLSRGLQNIKLQQNWQFSHKPKNADICTLLSQLATLLRAAVPLKNS
LQILLQNCTNIALNRWLRCLLQEIESGLAFSQALEQQGLYLTYQERQLIQVGEMTGKLAAVCHEIAQHKQQALALQRKIQ
KILLYPLLVLGISLILTALLLLFIVPQFAAMYDNSNAQLPVFTQVLLALSQGLQDYWFALLMFIALTVALIRFRLKHSPW
LNRQKNRLINSIPLLNRIVQLSRLVGFSRSLFLMLQAGIPLNQALQSFLPKQQSWQSKPQQQGDWLLITEVQSALHWIQQ
GYPFSASVSGQIFPPAAQQMLQVGEQSGQLPKMLQFIANDHQQQLDHQIDLLSQMLEPLLMVIIGGLIGLIMLGMYLPIF
NMGSLVQ

Nucleotide

• Length: 1224 bp

>NTDB_id=189127 BBH51_RS03390 WP_005540455.1 677146..678369(-) (pilC) [Aggregatibacter actinomycetemcomitans strain IDH781]
ATGACTAAATTGAAACTGTTTCAATGGCGCGGCGTTAATCGCTTGCAGCAAAAACAAAAAGGCTTAATCGTGGCGGAAAC
GGAGGTGATGGCACAACAACAGCTGCTTTCACGTGGGTTGCAAAACATCAAATTGCAACAAAACTGGCAATTCAGCCACA
AACCGAAAAATGCCGACATCTGCACCCTGCTTTCCCAACTGGCGACGCTATTACGAGCCGCCGTGCCGCTGAAAAACAGC
CTGCAAATTTTATTGCAAAATTGTACCAATATTGCGTTGAATCGCTGGCTACGCTGCTTGCTACAGGAGATTGAAAGCGG
CTTGGCATTTTCTCAAGCATTGGAACAACAAGGGTTATACTTAACCTATCAGGAACGCCAACTGATTCAGGTGGGTGAAA
TGACAGGCAAACTTGCCGCCGTCTGTCATGAAATCGCACAACATAAACAACAGGCGCTGGCGTTGCAGCGTAAAATTCAG
AAAATCCTGCTTTATCCGTTGCTGGTGCTCGGAATCTCATTGATTTTGACCGCACTTTTATTGCTGTTCATCGTGCCGCA
ATTTGCCGCCATGTATGACAACAGCAACGCGCAACTGCCCGTGTTCACGCAGGTTTTACTAGCCCTTTCCCAAGGCTTGC
AGGATTATTGGTTCGCGCTACTCATGTTTATTGCGCTGACCGTGGCGTTAATTCGCTTTCGCCTCAAACATTCGCCTTGG
CTTAACCGACAAAAAAACCGGCTGATTAACAGTATTCCGTTGCTTAATCGTATCGTACAACTCTCCCGCCTGGTGGGATT
CAGTCGCAGCTTGTTTTTGATGTTACAGGCAGGTATTCCGCTGAATCAGGCGCTGCAATCTTTTCTACCGAAGCAACAAA
GCTGGCAAAGCAAACCGCAACAGCAAGGGGATTGGCTATTAATTACAGAAGTGCAATCGGCACTGCATTGGATTCAACAA
GGCTATCCGTTCTCCGCCAGCGTAAGCGGACAAATCTTCCCGCCGGCGGCACAGCAAATGCTGCAAGTCGGCGAACAAAG
CGGTCAATTGCCGAAAATGCTGCAATTTATCGCCAACGATCATCAGCAACAGTTGGATCACCAAATCGATCTGCTGTCAC
AAATGCTGGAACCGTTATTGATGGTGATTATCGGCGGGCTGATCGGCTTGATTATGCTCGGTATGTATTTACCGATTTTC
AACATGGGCTCGCTGGTGCAATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (267-398)

• Type II secretion system (T2SS), protein F (T2SSF) (64-186)

3D structure

• AlphaFold DB: Q8KRY4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilC	Haemophilus influenzae Rd KW20	63.145	100	0.631
pilC	Haemophilus influenzae 86-028NP	62.899	100	0.629
pilC	Glaesserella parasuis strain SC1401	39.066	100	0.391