Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   BBP08_RS00660 Genome accession   NZ_CP016501
Coordinates   126537..127226 (+) Length   229 a.a.
NCBI ID   WP_000516680.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain WC1535     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 121537..132226
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BBP08_RS00635 (BBP08_00575) - 121964..123343 (-) 1380 WP_000680112.1 TrkH family potassium uptake protein -
  BBP08_RS00640 (BBP08_00580) rsmG 123358..124071 (-) 714 WP_000188795.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  BBP08_RS00645 (BBP08_00585) - 124199..124753 (+) 555 WP_000537055.1 LemA family protein -
  BBP08_RS00650 (BBP08_00590) htpX 124774..125664 (+) 891 WP_000966817.1 zinc metalloprotease HtpX -
  BBP08_RS00655 (BBP08_00595) - 125769..126302 (+) 534 WP_000927543.1 DUF177 domain-containing protein -
  BBP08_RS00660 (BBP08_00600) covR 126537..127226 (+) 690 WP_000516680.1 response regulator transcription factor Regulator
  BBP08_RS00665 (BBP08_00605) - 127216..128721 (+) 1506 WP_000791116.1 HAMP domain-containing histidine kinase -
  BBP08_RS00670 (BBP08_00610) nrdR 128870..129349 (+) 480 WP_001203682.1 transcriptional regulator NrdR -
  BBP08_RS00675 (BBP08_00615) - 129349..130524 (+) 1176 WP_000074512.1 DnaD domain protein -
  BBP08_RS00680 (BBP08_00620) dnaI 130521..131423 (+) 903 WP_000843627.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26559.61 Da        Isoelectric Point: 4.8094

>NTDB_id=188610 BBP08_RS00660 WP_000516680.1 126537..127226(+) (covR) [Streptococcus agalactiae strain WC1535]
MGKKILIIEDEKNLARFVSLELLHEGYDVVVETNGREGLDTALEKDFDLILLDLMLPEMDGFEITRRLQAEKTTYIMMMT
ARDSVMDIVAGLDRGADDYIVKPFAIEELLARVRAIFRRQEIETKTKEKGDSGSFRDLSLNTHNRSAMRGDEEISLTKRE
FDLLNVLMINMNRVMTREELLEHVWKYDVAAETNVVDVYIRYLRGKIDIPGRESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=188610 BBP08_RS00660 WP_000516680.1 126537..127226(+) (covR) [Streptococcus agalactiae strain WC1535]
ATGGGTAAAAAGATCTTAATAATCGAAGATGAGAAAAATTTAGCTCGCTTCGTCTCGTTAGAACTACTACATGAAGGATA
TGATGTTGTTGTTGAAACAAACGGTCGTGAAGGATTGGACACAGCATTAGAAAAAGATTTTGATTTGATTCTACTGGATT
TAATGCTTCCAGAGATGGATGGTTTCGAAATCACACGTCGCCTGCAGGCTGAAAAAACAACCTATATCATGATGATGACA
GCACGTGATTCTGTTATGGATATTGTAGCTGGTCTTGATCGTGGAGCAGATGATTATATTGTTAAGCCGTTTGCAATCGA
AGAATTATTAGCACGTGTTAGAGCGATTTTCCGACGCCAAGAAATTGAAACGAAGACAAAAGAAAAAGGTGATAGTGGTA
GTTTCCGTGATTTGTCATTAAATACTCATAATCGTTCAGCGATGCGTGGTGATGAGGAAATTTCACTAACAAAACGTGAA
TTTGATTTGTTGAATGTCTTGATGATAAATATGAATCGTGTTATGACACGAGAAGAGTTGCTAGAACATGTTTGGAAATA
CGATGTGGCAGCAGAGACAAACGTTGTTGATGTTTATATCCGTTACCTAAGAGGTAAAATTGATATCCCAGGTCGTGAAT
CATATATTCAAACTGTTCGCGGAATGGGCTATGTGATTCGTGAAAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

79.476

100

0.795
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.228

99.563

0.659
  vicR Streptococcus mutans UA159

45.455

100

0.459
  micA Streptococcus pneumoniae Cp1015

43.478

100

0.437

Multiple sequence alignment