Detailed information
Bioinformatically predicted
Overview
| Name | amiA3 | Type | Regulator |
| Locus tag | BAY21_RS07575 | Genome accession | NZ_CP016439 |
| Coordinates | 1418266..1420233 (+) | Length | 655 a.a. |
| NCBI ID | WP_011227411.1 | Uniprot ID | - |
| Organism | Streptococcus thermophilus strain CS8 | ||
| Function | binding to XIP (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1372109..1443880 | 1418266..1420233 | within | 0 |
| IScluster/Tn | 1414170..1421379 | 1418266..1420233 | within | 0 |
Gene organization within MGE regions
Location: 1372109..1443880
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BAY21_RS07340 (BAY21_07340) | - | 1372207..1372947 (-) | 741 | WP_002945131.1 | amino acid ABC transporter ATP-binding protein | - |
| BAY21_RS07345 (BAY21_07345) | - | 1372947..1375157 (-) | 2211 | WP_011226350.1 | ABC transporter substrate-binding protein/permease | - |
| BAY21_RS11450 | - | 1375356..1376292 (+) | 937 | Protein_1385 | CPBP family intramembrane glutamic endopeptidase | - |
| BAY21_RS07365 (BAY21_07365) | uvrB | 1376979..1378970 (+) | 1992 | WP_002953358.1 | excinuclease ABC subunit UvrB | - |
| BAY21_RS07370 (BAY21_07370) | - | 1379015..1379479 (+) | 465 | WP_011226345.1 | 8-oxo-dGTP diphosphatase | - |
| BAY21_RS07375 (BAY21_07375) | - | 1379693..1380523 (+) | 831 | WP_041828297.1 | transporter substrate-binding domain-containing protein | - |
| BAY21_RS07380 (BAY21_07380) | - | 1380520..1381317 (+) | 798 | WP_059257394.1 | transporter substrate-binding domain-containing protein | - |
| BAY21_RS07385 (BAY21_07385) | - | 1381664..1382773 (+) | 1110 | WP_041827078.1 | aminotransferase | - |
| BAY21_RS07390 (BAY21_07390) | - | 1382866..1383660 (+) | 795 | WP_011227442.1 | ABC transporter substrate-binding protein | - |
| BAY21_RS07395 (BAY21_07395) | - | 1383766..1384719 (-) | 954 | WP_041826943.1 | IS30 family transposase | - |
| BAY21_RS07400 (BAY21_07400) | rpsU | 1385100..1385276 (+) | 177 | WP_011226340.1 | 30S ribosomal protein S21 | - |
| BAY21_RS07405 (BAY21_07405) | dnaG | 1385648..1387459 (+) | 1812 | WP_011227441.1 | DNA primase | - |
| BAY21_RS07410 (BAY21_07410) | rpoD | 1387463..1388572 (+) | 1110 | WP_011227440.1 | RNA polymerase sigma factor RpoD | - |
| BAY21_RS07415 (BAY21_07415) | - | 1388626..1388961 (+) | 336 | WP_002891474.1 | metal-sulfur cluster assembly factor | - |
| BAY21_RS07420 (BAY21_07420) | - | 1388971..1389897 (+) | 927 | WP_011227439.1 | glycosyltransferase family 2 protein | - |
| BAY21_RS07425 (BAY21_07425) | rfbD | 1390015..1390866 (+) | 852 | WP_014621820.1 | dTDP-4-dehydrorhamnose reductase | - |
| BAY21_RS07430 (BAY21_07430) | - | 1390987..1392246 (+) | 1260 | WP_011227438.1 | oligosaccharide flippase family protein | - |
| BAY21_RS07435 (BAY21_07435) | - | 1392243..1393229 (+) | 987 | WP_011227437.1 | glycosyltransferase family 2 protein | - |
| BAY21_RS07440 (BAY21_07440) | - | 1393294..1393766 (+) | 473 | Protein_1401 | glycosyltransferase family 2 protein | - |
| BAY21_RS07445 (BAY21_07445) | - | 1393850..1394545 (+) | 696 | WP_173405413.1 | glycosyltransferase family 2 protein | - |
| BAY21_RS07450 (BAY21_07450) | - | 1394551..1394883 (+) | 333 | WP_011227433.1 | DUF2304 domain-containing protein | - |
| BAY21_RS07455 (BAY21_07455) | - | 1394884..1395666 (+) | 783 | WP_011227432.1 | glycosyltransferase family A protein | - |
| BAY21_RS07460 (BAY21_07460) | cps2T | 1395785..1396933 (+) | 1149 | WP_011227431.1 | beta 1-4 rhamnosyltransferase Cps2T | - |
| BAY21_RS07465 (BAY21_07465) | - | 1396930..1397871 (+) | 942 | WP_011227430.1 | glycosyltransferase family 2 protein | - |
| BAY21_RS07470 (BAY21_07470) | - | 1397871..1398677 (+) | 807 | WP_011227429.1 | ABC transporter permease | - |
| BAY21_RS07475 (BAY21_07475) | - | 1398677..1399879 (+) | 1203 | WP_011227428.1 | ABC transporter ATP-binding protein | - |
| BAY21_RS07480 (BAY21_07480) | - | 1399897..1401597 (+) | 1701 | WP_041827077.1 | glycosyltransferase family 4 protein | - |
| BAY21_RS07485 (BAY21_07485) | - | 1401599..1403344 (+) | 1746 | WP_011227426.1 | rhamnan synthesis F family protein | - |
| BAY21_RS07490 (BAY21_07490) | - | 1403493..1404833 (+) | 1341 | WP_231108743.1 | DUF2142 domain-containing protein | - |
| BAY21_RS07495 (BAY21_07495) | radC | 1405012..1405698 (+) | 687 | WP_011227424.1 | RadC family protein | - |
| BAY21_RS07500 (BAY21_07500) | - | 1405751..1406446 (-) | 696 | WP_011227423.1 | gamma-glutamyl-gamma-aminobutyrate hydrolase family protein | - |
| BAY21_RS07505 (BAY21_07505) | - | 1406439..1407098 (-) | 660 | WP_041827076.1 | redox-sensing transcriptional repressor Rex | - |
| BAY21_RS07510 (BAY21_07510) | - | 1407242..1407589 (-) | 348 | WP_002948028.1 | DUF1831 domain-containing protein | - |
| BAY21_RS10410 (BAY21_07515) | - | 1407591..1408703 (-) | 1113 | WP_002948029.1 | cysteine desulfurase family protein | - |
| BAY21_RS10415 (BAY21_07520) | - | 1408707..1409678 (-) | 972 | WP_002951446.1 | ribose-phosphate diphosphokinase | - |
| BAY21_RS07525 (BAY21_07525) | - | 1410041..1410616 (-) | 576 | WP_002951444.1 | CYTH domain-containing protein | - |
| BAY21_RS07530 (BAY21_07530) | - | 1410712..1411386 (+) | 675 | WP_002951443.1 | GTP pyrophosphokinase | - |
| BAY21_RS07535 (BAY21_07535) | - | 1411358..1412194 (+) | 837 | WP_041827075.1 | NAD kinase | - |
| BAY21_RS07540 (BAY21_07540) | - | 1412191..1413087 (+) | 897 | WP_011226316.1 | RluA family pseudouridine synthase | - |
| BAY21_RS07545 (BAY21_07545) | pta | 1413101..1414084 (+) | 984 | WP_011227420.1 | phosphate acetyltransferase | - |
| BAY21_RS10020 | - | 1414170..1415522 (+) | 1353 | Protein_1423 | IS3 family transposase | - |
| BAY21_RS07560 (BAY21_07560) | - | 1415568..1416773 (-) | 1206 | WP_011227415.1 | OFA family MFS transporter | - |
| BAY21_RS07565 (BAY21_07565) | - | 1417122..1417436 (+) | 315 | Protein_1425 | TatD family hydrolase | - |
| BAY21_RS11180 | - | 1417468..1417878 (+) | 411 | Protein_1426 | ATP-binding cassette domain-containing protein | - |
| BAY21_RS10030 | - | 1417872..1418062 (+) | 191 | Protein_1427 | IS3 family transposase | - |
| BAY21_RS07575 (BAY21_07575) | amiA3 | 1418266..1420233 (+) | 1968 | WP_011227411.1 | peptide ABC transporter substrate-binding protein | Regulator |
| BAY21_RS10035 | - | 1420278..1421527 (-) | 1250 | Protein_1429 | ISL3 family transposase | - |
| BAY21_RS07580 (BAY21_07580) | - | 1421883..1423849 (+) | 1967 | Protein_1430 | peptide ABC transporter substrate-binding protein | - |
| BAY21_RS07585 (BAY21_07585) | amiC | 1423911..1425404 (+) | 1494 | WP_011227407.1 | ABC transporter permease | Regulator |
| BAY21_RS07590 (BAY21_07590) | amiD | 1425404..1426330 (+) | 927 | WP_002946409.1 | oligopeptide ABC transporter permease OppC | Regulator |
| BAY21_RS07595 (BAY21_07595) | amiE | 1426340..1427425 (+) | 1086 | WP_011226304.1 | ABC transporter ATP-binding protein | Regulator |
| BAY21_RS07600 (BAY21_07600) | amiF | 1427418..1428347 (+) | 930 | WP_002951426.1 | ATP-binding cassette domain-containing protein | Regulator |
| BAY21_RS07605 (BAY21_07605) | - | 1428397..1429182 (-) | 786 | WP_002951425.1 | hypothetical protein | - |
| BAY21_RS07610 (BAY21_07610) | - | 1429194..1429892 (-) | 699 | WP_011226301.1 | ABC transporter ATP-binding protein | - |
| BAY21_RS07615 (BAY21_07615) | - | 1429897..1430274 (-) | 378 | WP_011226300.1 | GntR family transcriptional regulator | - |
| BAY21_RS07620 (BAY21_07620) | - | 1430457..1431251 (+) | 795 | WP_011227406.1 | HAD hydrolase family protein | - |
| BAY21_RS07625 (BAY21_07625) | - | 1431244..1432059 (+) | 816 | WP_011227405.1 | Cof-type HAD-IIB family hydrolase | - |
| BAY21_RS07630 (BAY21_07630) | ftsY | 1432073..1433464 (+) | 1392 | WP_011226297.1 | signal recognition particle-docking protein FtsY | - |
| BAY21_RS07635 (BAY21_07635) | gmk | 1433697..1434326 (+) | 630 | WP_011226296.1 | guanylate kinase | - |
| BAY21_RS07640 (BAY21_07640) | rpoZ | 1434348..1434662 (+) | 315 | WP_002951415.1 | DNA-directed RNA polymerase subunit omega | - |
| BAY21_RS07645 (BAY21_07645) | - | 1434804..1437200 (+) | 2397 | WP_011227404.1 | primosomal protein N' | - |
| BAY21_RS07650 (BAY21_07650) | fmt | 1437218..1438153 (+) | 936 | WP_002951411.1 | methionyl-tRNA formyltransferase | - |
| BAY21_RS07655 (BAY21_07655) | rsmB | 1438143..1439464 (+) | 1322 | Protein_1445 | 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB | - |
| BAY21_RS07660 (BAY21_07660) | - | 1439508..1440245 (+) | 738 | WP_002946881.1 | Stp1/IreP family PP2C-type Ser/Thr phosphatase | - |
| BAY21_RS07665 (BAY21_07665) | stkP/pknB | 1440245..1442116 (+) | 1872 | WP_011226292.1 | Stk1 family PASTA domain-containing Ser/Thr kinase | Regulator |
| BAY21_RS11185 | - | 1442753..1442908 (+) | 156 | WP_011226290.1 | ion channel | - |
| BAY21_RS07670 (BAY21_07670) | liaF | 1443174..1443872 (+) | 699 | WP_011227403.1 | cell wall-active antibiotics response protein LiaF | - |
Sequence
Protein
Download Length: 655 a.a. Molecular weight: 71933.91 Da Isoelectric Point: 5.2648
>NTDB_id=188269 BAY21_RS07575 WP_011227411.1 1418266..1420233(+) (amiA3) [Streptococcus thermophilus strain CS8]
MKKSKWLALAGAALLGVGVLAACSSKSNTSGTTYGYVYSSDPETLDYITSNTGPTKSVVTNGVDGLMEADKYGNLVPSVA
EDWSVSKDGLTYTYKIRKGIKWYTSEGEEYANVTAKDFVTGLKHAADSKAGGIYLVQDSIAGLSDYLSGTNKDFSNVGVK
AIDDYTLQYTLKKPEPYWNSKTTYSLLFPVNEDFLKNKGKDFGKSTDPTSILYNGPFLLKSLTAKSSIELVKNEHYWDKK
NVHFDAIKFSYYDGSDQDALVRGFTDGAYNFARVFPTSSNYASVEKKYKDNIYYTAPGASTSAIGINIDRQSYKYTAKKT
DSEKSSTKKALLNKDFRQAINFAIDRKAYQSQINGKDGATLAVRNLFVPSDFVSAGDKTFGDLVTEKMSSYGDEWSGVNF
ADSQDGLYNAEKAKTEFAKAKDALQADGVQFPIHLDLPVDQSSKLNVAQAQSLKQTIEKSLGSENVVIDINQLSSDDLEN
VTLNAANAAAEDWDISNSVAWAPDYQDPSTYLDIFKTTSSENTKAFMGYDDPNNAAAAQVGLKDYDALLNSAASETSDLN
VRYDRYAQAQAWLEDSSLVIPLTVGNGAAPAISRLTPFTGASIQVGDKGSSYVKYVKSQEKVVTKKEYEQSREKWLKEKK
ESNEKAQKDLEKHVK
MKKSKWLALAGAALLGVGVLAACSSKSNTSGTTYGYVYSSDPETLDYITSNTGPTKSVVTNGVDGLMEADKYGNLVPSVA
EDWSVSKDGLTYTYKIRKGIKWYTSEGEEYANVTAKDFVTGLKHAADSKAGGIYLVQDSIAGLSDYLSGTNKDFSNVGVK
AIDDYTLQYTLKKPEPYWNSKTTYSLLFPVNEDFLKNKGKDFGKSTDPTSILYNGPFLLKSLTAKSSIELVKNEHYWDKK
NVHFDAIKFSYYDGSDQDALVRGFTDGAYNFARVFPTSSNYASVEKKYKDNIYYTAPGASTSAIGINIDRQSYKYTAKKT
DSEKSSTKKALLNKDFRQAINFAIDRKAYQSQINGKDGATLAVRNLFVPSDFVSAGDKTFGDLVTEKMSSYGDEWSGVNF
ADSQDGLYNAEKAKTEFAKAKDALQADGVQFPIHLDLPVDQSSKLNVAQAQSLKQTIEKSLGSENVVIDINQLSSDDLEN
VTLNAANAAAEDWDISNSVAWAPDYQDPSTYLDIFKTTSSENTKAFMGYDDPNNAAAAQVGLKDYDALLNSAASETSDLN
VRYDRYAQAQAWLEDSSLVIPLTVGNGAAPAISRLTPFTGASIQVGDKGSSYVKYVKSQEKVVTKKEYEQSREKWLKEKK
ESNEKAQKDLEKHVK
Nucleotide
Download Length: 1968 bp
>NTDB_id=188269 BAY21_RS07575 WP_011227411.1 1418266..1420233(+) (amiA3) [Streptococcus thermophilus strain CS8]
ATGAAAAAAAGCAAATGGTTGGCTCTCGCGGGTGCAGCACTTCTAGGTGTTGGTGTGTTAGCGGCTTGTTCATCTAAATC
AAACACTAGCGGAACTACTTATGGTTATGTTTACAGTTCGGATCCAGAAACTTTGGATTATATTACATCAAATACGGGAC
CTACAAAATCTGTTGTGACAAATGGTGTAGATGGACTTATGGAAGCGGACAAATATGGTAATCTTGTTCCATCAGTAGCT
GAAGACTGGTCTGTGTCTAAAGATGGTCTTACTTATACCTATAAAATTCGTAAAGGGATCAAATGGTATACTTCTGAAGG
TGAAGAGTACGCTAATGTTACTGCTAAGGACTTTGTAACGGGTCTTAAACATGCTGCGGATTCCAAAGCAGGTGGTATCT
ATTTGGTTCAAGATTCTATTGCTGGATTGTCTGACTATCTCTCTGGTACCAATAAAGATTTCTCGAATGTGGGTGTCAAG
GCAATTGATGACTATACTTTGCAGTACACGCTTAAGAAACCAGAACCATACTGGAACTCTAAGACAACTTATAGTTTGCT
TTTCCCAGTAAATGAGGACTTCCTCAAGAATAAGGGAAAAGATTTTGGTAAATCAACAGACCCAACCTCTATCCTTTATA
ATGGACCTTTCCTTCTCAAATCTTTGACAGCTAAATCTTCAATTGAGTTGGTTAAGAATGAACATTATTGGGACAAGAAA
AATGTACACTTTGATGCCATCAAATTCTCATATTATGATGGTTCGGATCAAGATGCTCTAGTACGTGGTTTCACTGATGG
TGCTTATAATTTTGCTCGTGTCTTTCCAACGAGTTCAAACTATGCTTCTGTAGAGAAGAAATATAAAGATAATATTTATT
ACACAGCACCAGGTGCGTCTACATCAGCTATTGGTATTAATATTGACCGTCAAAGTTACAAGTATACAGCCAAAAAGACG
GATTCTGAAAAATCATCAACCAAGAAAGCCCTTCTAAACAAGGACTTCCGTCAAGCAATTAACTTTGCCATTGACCGTAA
GGCCTATCAATCACAAATTAACGGTAAAGATGGTGCAACTCTAGCTGTTCGTAACCTCTTTGTGCCTTCTGATTTTGTGA
GTGCAGGTGATAAGACCTTCGGAGATCTTGTAACAGAGAAAATGTCTTCATATGGGGATGAATGGTCAGGTGTGAATTTT
GCTGATAGTCAAGATGGCCTCTACAATGCTGAAAAAGCTAAGACTGAGTTTGCCAAAGCTAAGGATGCTCTCCAAGCAGA
TGGTGTTCAATTCCCAATTCATTTGGACCTTCCAGTTGACCAAAGCTCTAAACTTAATGTTGCCCAAGCCCAATCTTTGA
AACAAACCATTGAAAAATCATTGGGTAGCGAAAATGTTGTTATAGATATTAACCAATTGTCATCTGATGATTTGGAAAAT
GTAACACTTAATGCAGCCAACGCAGCAGCAGAAGACTGGGATATTTCAAATAGTGTCGCTTGGGCGCCAGATTACCAAGA
TCCATCAACCTACCTTGATATCTTTAAGACAACTTCAAGTGAAAACACTAAGGCTTTCATGGGTTATGATGATCCAAATA
ATGCGGCAGCAGCCCAAGTGGGACTCAAAGACTATGATGCCTTGCTGAATTCTGCAGCTTCAGAAACAAGTGACCTTAAT
GTTCGTTACGATCGTTATGCTCAAGCTCAAGCATGGTTGGAGGACAGTTCGCTTGTGATTCCATTGACTGTTGGTAATGG
TGCGGCACCAGCTATCTCACGCTTGACACCGTTTACCGGTGCTAGCATCCAGGTGGGTGATAAGGGCTCATCCTACGTCA
AATATGTGAAATCACAAGAAAAAGTAGTTACTAAGAAAGAATATGAACAAAGTCGTGAAAAATGGCTTAAAGAAAAGAAA
GAATCTAACGAAAAAGCTCAAAAAGATCTTGAGAAACACGTTAAATAA
ATGAAAAAAAGCAAATGGTTGGCTCTCGCGGGTGCAGCACTTCTAGGTGTTGGTGTGTTAGCGGCTTGTTCATCTAAATC
AAACACTAGCGGAACTACTTATGGTTATGTTTACAGTTCGGATCCAGAAACTTTGGATTATATTACATCAAATACGGGAC
CTACAAAATCTGTTGTGACAAATGGTGTAGATGGACTTATGGAAGCGGACAAATATGGTAATCTTGTTCCATCAGTAGCT
GAAGACTGGTCTGTGTCTAAAGATGGTCTTACTTATACCTATAAAATTCGTAAAGGGATCAAATGGTATACTTCTGAAGG
TGAAGAGTACGCTAATGTTACTGCTAAGGACTTTGTAACGGGTCTTAAACATGCTGCGGATTCCAAAGCAGGTGGTATCT
ATTTGGTTCAAGATTCTATTGCTGGATTGTCTGACTATCTCTCTGGTACCAATAAAGATTTCTCGAATGTGGGTGTCAAG
GCAATTGATGACTATACTTTGCAGTACACGCTTAAGAAACCAGAACCATACTGGAACTCTAAGACAACTTATAGTTTGCT
TTTCCCAGTAAATGAGGACTTCCTCAAGAATAAGGGAAAAGATTTTGGTAAATCAACAGACCCAACCTCTATCCTTTATA
ATGGACCTTTCCTTCTCAAATCTTTGACAGCTAAATCTTCAATTGAGTTGGTTAAGAATGAACATTATTGGGACAAGAAA
AATGTACACTTTGATGCCATCAAATTCTCATATTATGATGGTTCGGATCAAGATGCTCTAGTACGTGGTTTCACTGATGG
TGCTTATAATTTTGCTCGTGTCTTTCCAACGAGTTCAAACTATGCTTCTGTAGAGAAGAAATATAAAGATAATATTTATT
ACACAGCACCAGGTGCGTCTACATCAGCTATTGGTATTAATATTGACCGTCAAAGTTACAAGTATACAGCCAAAAAGACG
GATTCTGAAAAATCATCAACCAAGAAAGCCCTTCTAAACAAGGACTTCCGTCAAGCAATTAACTTTGCCATTGACCGTAA
GGCCTATCAATCACAAATTAACGGTAAAGATGGTGCAACTCTAGCTGTTCGTAACCTCTTTGTGCCTTCTGATTTTGTGA
GTGCAGGTGATAAGACCTTCGGAGATCTTGTAACAGAGAAAATGTCTTCATATGGGGATGAATGGTCAGGTGTGAATTTT
GCTGATAGTCAAGATGGCCTCTACAATGCTGAAAAAGCTAAGACTGAGTTTGCCAAAGCTAAGGATGCTCTCCAAGCAGA
TGGTGTTCAATTCCCAATTCATTTGGACCTTCCAGTTGACCAAAGCTCTAAACTTAATGTTGCCCAAGCCCAATCTTTGA
AACAAACCATTGAAAAATCATTGGGTAGCGAAAATGTTGTTATAGATATTAACCAATTGTCATCTGATGATTTGGAAAAT
GTAACACTTAATGCAGCCAACGCAGCAGCAGAAGACTGGGATATTTCAAATAGTGTCGCTTGGGCGCCAGATTACCAAGA
TCCATCAACCTACCTTGATATCTTTAAGACAACTTCAAGTGAAAACACTAAGGCTTTCATGGGTTATGATGATCCAAATA
ATGCGGCAGCAGCCCAAGTGGGACTCAAAGACTATGATGCCTTGCTGAATTCTGCAGCTTCAGAAACAAGTGACCTTAAT
GTTCGTTACGATCGTTATGCTCAAGCTCAAGCATGGTTGGAGGACAGTTCGCTTGTGATTCCATTGACTGTTGGTAATGG
TGCGGCACCAGCTATCTCACGCTTGACACCGTTTACCGGTGCTAGCATCCAGGTGGGTGATAAGGGCTCATCCTACGTCA
AATATGTGAAATCACAAGAAAAAGTAGTTACTAAGAAAGAATATGAACAAAGTCGTGAAAAATGGCTTAAAGAAAAGAAA
GAATCTAACGAAAAAGCTCAAAAAGATCTTGAGAAACACGTTAAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| amiA3 | Streptococcus thermophilus LMG 18311 |
98.478 |
100 |
0.988 |
| amiA3 | Streptococcus thermophilus LMD-9 |
97.565 |
100 |
0.979 |
| amiA | Streptococcus salivarius strain HSISS4 |
90.549 |
100 |
0.907 |