Detailed information
Bioinformatically predicted
Overview
| Name | amiA3 | Type | Regulator |
| Locus tag | BBD27_RS07180 | Genome accession | NZ_CP016394 |
| Coordinates | 1347100..1349073 (+) | Length | 657 a.a. |
| NCBI ID | WP_011681419.1 | Uniprot ID | - |
| Organism | Streptococcus thermophilus strain ND07 | ||
| Function | binding to XIP (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1301614..1372647 | 1347100..1349073 | within | 0 |
| IScluster/Tn | 1341766..1350295 | 1347100..1349073 | within | 0 |
Gene organization within MGE regions
Location: 1301614..1372647
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BBD27_RS06940 (BBD27_1366) | - | 1301711..1302451 (-) | 741 | WP_024703961.1 | amino acid ABC transporter ATP-binding protein | - |
| BBD27_RS06945 (BBD27_1367) | - | 1302451..1304661 (-) | 2211 | WP_014727645.1 | ABC transporter substrate-binding protein/permease | - |
| BBD27_RS10305 | - | 1304860..1305796 (+) | 937 | Protein_1304 | CPBP family intramembrane glutamic endopeptidase | - |
| BBD27_RS06960 (BBD27_1372) | - | 1305869..1306336 (+) | 468 | WP_014608580.1 | hypothetical protein | - |
| BBD27_RS06965 (BBD27_1373) | uvrB | 1306483..1308474 (+) | 1992 | WP_014608579.1 | excinuclease ABC subunit UvrB | - |
| BBD27_RS06970 (BBD27_1374) | - | 1308519..1308983 (+) | 465 | WP_011681454.1 | 8-oxo-dGTP diphosphatase | - |
| BBD27_RS06975 (BBD27_1375) | - | 1309197..1310027 (+) | 831 | WP_014621829.1 | transporter substrate-binding domain-containing protein | - |
| BBD27_RS06980 (BBD27_1376) | - | 1310024..1310821 (+) | 798 | WP_014621828.1 | transporter substrate-binding domain-containing protein | - |
| BBD27_RS06985 (BBD27_1377) | - | 1311169..1312278 (+) | 1110 | WP_024703959.1 | aminotransferase | - |
| BBD27_RS06990 (BBD27_1378) | - | 1312340..1313134 (+) | 795 | WP_023909836.1 | ABC transporter substrate-binding protein | - |
| BBD27_RS06995 (BBD27_1379) | rpsU | 1313328..1313504 (+) | 177 | WP_011681449.1 | 30S ribosomal protein S21 | - |
| BBD27_RS07000 (BBD27_1380) | mscL | 1313664..1313744 (-) | 81 | Protein_1313 | large conductance mechanosensitive channel protein MscL | - |
| BBD27_RS07005 (BBD27_1381) | dnaG | 1313887..1315698 (+) | 1812 | WP_024703958.1 | DNA primase | - |
| BBD27_RS07010 (BBD27_1382) | rpoD | 1315702..1316811 (+) | 1110 | WP_011227440.1 | RNA polymerase sigma factor RpoD | - |
| BBD27_RS07015 (BBD27_1383) | - | 1316865..1317200 (+) | 336 | WP_024703957.1 | metal-sulfur cluster assembly factor | - |
| BBD27_RS07020 (BBD27_1384) | - | 1317210..1318136 (+) | 927 | WP_024703956.1 | glycosyltransferase family 2 protein | - |
| BBD27_RS07025 (BBD27_1385) | - | 1318249..1319583 (+) | 1335 | WP_024703955.1 | DUF3329 domain-containing protein | - |
| BBD27_RS07030 (BBD27_1386) | rfbD | 1319660..1320511 (+) | 852 | WP_014621820.1 | dTDP-4-dehydrorhamnose reductase | - |
| BBD27_RS07035 (BBD27_1387) | - | 1320588..1321283 (+) | 696 | WP_024703954.1 | glycosyltransferase family 2 protein | - |
| BBD27_RS07040 (BBD27_1388) | - | 1321289..1321621 (+) | 333 | WP_011226332.1 | DUF2304 domain-containing protein | - |
| BBD27_RS07045 (BBD27_1389) | - | 1321614..1322888 (+) | 1275 | WP_024703953.1 | lipopolysaccharide biosynthesis protein | - |
| BBD27_RS07050 (BBD27_1390) | - | 1322888..1323898 (+) | 1011 | WP_024703952.1 | glycosyltransferase | - |
| BBD27_RS07055 (BBD27_1391) | - | 1323905..1325446 (+) | 1542 | WP_024703951.1 | DUF2142 domain-containing protein | - |
| BBD27_RS07060 (BBD27_1392) | cps2T | 1325553..1326701 (+) | 1149 | WP_024703950.1 | beta 1-4 rhamnosyltransferase Cps2T | - |
| BBD27_RS07065 (BBD27_1393) | - | 1326698..1327654 (+) | 957 | WP_024703949.1 | glycosyltransferase family 2 protein | - |
| BBD27_RS07070 (BBD27_1394) | - | 1327638..1328447 (+) | 810 | WP_024703948.1 | ABC transporter permease | - |
| BBD27_RS07075 (BBD27_1395) | - | 1328447..1329652 (+) | 1206 | WP_014727633.1 | ABC transporter ATP-binding protein | - |
| BBD27_RS07080 (BBD27_1396) | - | 1329672..1330739 (+) | 1068 | WP_024703947.1 | glycosyltransferase family 2 protein | - |
| BBD27_RS07085 (BBD27_1397) | - | 1330736..1332520 (+) | 1785 | WP_024703946.1 | rhamnan synthesis F family protein | - |
| BBD27_RS07090 (BBD27_1398) | radC | 1332569..1333255 (+) | 687 | WP_014727630.1 | RadC family protein | - |
| BBD27_RS07095 (BBD27_1399) | - | 1333308..1334003 (-) | 696 | WP_024703945.1 | gamma-glutamyl-gamma-aminobutyrate hydrolase family protein | - |
| BBD27_RS07100 (BBD27_1400) | - | 1333996..1334655 (-) | 660 | WP_024703944.1 | redox-sensing transcriptional repressor Rex | - |
| BBD27_RS07105 (BBD27_1401) | - | 1334799..1335146 (-) | 348 | WP_014608555.1 | DUF1831 domain-containing protein | - |
| BBD27_RS10790 (BBD27_1402) | - | 1335148..1336260 (-) | 1113 | WP_014608554.1 | cysteine desulfurase family protein | - |
| BBD27_RS10795 (BBD27_1403) | - | 1336264..1337235 (-) | 972 | WP_002951446.1 | ribose-phosphate diphosphokinase | - |
| BBD27_RS07120 (BBD27_1404) | - | 1337598..1338173 (-) | 576 | WP_002951444.1 | CYTH domain-containing protein | - |
| BBD27_RS07125 (BBD27_1405) | - | 1338269..1338943 (+) | 675 | WP_011681427.1 | GTP pyrophosphokinase | - |
| BBD27_RS07130 (BBD27_1406) | - | 1338915..1339751 (+) | 837 | WP_014608552.1 | NAD kinase | - |
| BBD27_RS07135 (BBD27_1407) | - | 1339748..1340644 (+) | 897 | WP_024703943.1 | RluA family pseudouridine synthase | - |
| BBD27_RS07140 (BBD27_1408) | pta | 1340658..1341641 (+) | 984 | WP_011227420.1 | phosphate acetyltransferase | - |
| BBD27_RS10315 | - | 1341766..1343079 (+) | 1314 | Protein_1342 | IS3 family transposase | - |
| BBD27_RS07155 (BBD27_1410) | - | 1343125..1344330 (-) | 1206 | WP_011681420.1 | OFA family MFS transporter | - |
| BBD27_RS07160 (BBD27_1411) | - | 1344676..1344990 (+) | 315 | Protein_1344 | TatD family hydrolase | - |
| BBD27_RS11520 | - | 1345022..1345432 (+) | 411 | Protein_1345 | ATP-binding cassette domain-containing protein | - |
| BBD27_RS10325 | - | 1345426..1345610 (+) | 185 | Protein_1346 | IS3 family transposase | - |
| BBD27_RS07180 (BBD27_1416) | amiA3 | 1347100..1349073 (+) | 1974 | WP_011681419.1 | peptide ABC transporter substrate-binding protein | Regulator |
| BBD27_RS07185 (BBD27_1417) | - | 1349118..1350295 (-) | 1178 | Protein_1349 | ISL3 family transposase | - |
| BBD27_RS07190 (BBD27_1418) | amiA | 1350651..1352618 (+) | 1968 | WP_024703940.1 | peptide ABC transporter substrate-binding protein | Regulator |
| BBD27_RS07195 (BBD27_1419) | amiC | 1352680..1354173 (+) | 1494 | WP_011681416.1 | ABC transporter permease | Regulator |
| BBD27_RS07200 (BBD27_1420) | amiD | 1354173..1355099 (+) | 927 | WP_002946409.1 | oligopeptide ABC transporter permease OppC | Regulator |
| BBD27_RS07205 (BBD27_1421) | amiE | 1355109..1356194 (+) | 1086 | WP_011226304.1 | ABC transporter ATP-binding protein | Regulator |
| BBD27_RS07210 (BBD27_1422) | amiF | 1356187..1357116 (+) | 930 | WP_002951426.1 | ATP-binding cassette domain-containing protein | Regulator |
| BBD27_RS07215 (BBD27_1423) | - | 1357166..1357951 (-) | 786 | WP_002951425.1 | hypothetical protein | - |
| BBD27_RS07220 (BBD27_1424) | - | 1357963..1358661 (-) | 699 | WP_023909821.1 | ABC transporter ATP-binding protein | - |
| BBD27_RS07225 (BBD27_1425) | - | 1358666..1359043 (-) | 378 | WP_011681413.1 | GntR family transcriptional regulator | - |
| BBD27_RS07230 (BBD27_1426) | - | 1359228..1360022 (+) | 795 | WP_011681412.1 | HAD-IIB family hydrolase | - |
| BBD27_RS07235 (BBD27_1427) | - | 1360015..1360830 (+) | 816 | WP_011226298.1 | Cof-type HAD-IIB family hydrolase | - |
| BBD27_RS07240 (BBD27_1428) | ftsY | 1360844..1362235 (+) | 1392 | WP_014608538.1 | signal recognition particle-docking protein FtsY | - |
| BBD27_RS07245 (BBD27_1429) | gmk | 1362461..1363090 (+) | 630 | WP_014608537.1 | guanylate kinase | - |
| BBD27_RS07250 (BBD27_1430) | rpoZ | 1363112..1363426 (+) | 315 | WP_002951415.1 | DNA-directed RNA polymerase subunit omega | - |
| BBD27_RS07255 (BBD27_1431) | - | 1363568..1365964 (+) | 2397 | WP_024703939.1 | primosomal protein N' | - |
| BBD27_RS07260 (BBD27_1432) | fmt | 1365982..1366917 (+) | 936 | WP_014608534.1 | methionyl-tRNA formyltransferase | - |
| BBD27_RS07265 (BBD27_1433) | rsmB | 1366907..1368229 (+) | 1323 | WP_014608533.1 | 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB | - |
| BBD27_RS07270 (BBD27_1434) | - | 1368273..1369010 (+) | 738 | WP_002946881.1 | Stp1/IreP family PP2C-type Ser/Thr phosphatase | - |
| BBD27_RS07275 (BBD27_1435) | stkP/pknB | 1369010..1370881 (+) | 1872 | WP_024703938.1 | Stk1 family PASTA domain-containing Ser/Thr kinase | Regulator |
| BBD27_RS11525 (BBD27_1437) | - | 1371519..1371686 (+) | 168 | WP_014608530.1 | potassium channel family protein | - |
| BBD27_RS07280 (BBD27_1438) | liaF | 1371941..1372639 (+) | 699 | WP_011226289.1 | cell wall-active antibiotics response protein LiaF | - |
Sequence
Protein
Download Length: 657 a.a. Molecular weight: 72221.23 Da Isoelectric Point: 5.1726
>NTDB_id=187856 BBD27_RS07180 WP_011681419.1 1347100..1349073(+) (amiA3) [Streptococcus thermophilus strain ND07]
MKKSKWLALAGVALLGVGVLAACSSKSNTSGTTYGYVYSSDPETLDYITSNTGPTKSVVTNGVDGLMEADKYGNLVPSVA
EDWSVSKDGLTYTYKIRKGIKWYTSEGEEYANVTAKDFVTGLKHAADSKAGGIYLVQDSIAGLSDYLSGTNKDFSNVGVK
AIDDYTLQYTLKQPEPYWNSKTTYSLLFPVNEDFLKNKGKDFGKSTDPTSILYNGPFLLKSLTAKSSIELVKNEHYWDKK
NVHFDAIKFSYYDGSDQDALVRGFTDGAYNFARVFPTSSNYASVEKKYKDNIFYTAPGASTSAIGINIDRQSYKYTAKKT
DSEKSSTKKALLNKDFRQAINFAIDRKAYQSQINGKDGATLGVRNLFVPSDFVSAGDKTFGDLVTEKMSSYGDEWSGVNL
ADSQDGLYNAEKAKTEFAKAKDALQADGVQFPIHLDLPVNQSSKLNVAQVQSLKQTIEKSLGSENVVIDINQLSSDDLEN
ATLNAANAAAEDWDISNSVGWAPDYQDPSTYLDIFKTTSSENTKAFMGYDDPNNAAAAQVGLKDYDALLNSAASETSDLN
VRYDRYAQAQAWLEDSSLVIPLTVGNGAAPVISRLTPFTGASLQVGDKNSSNDYIKYVKPQEKVVTKKEYEQSREKWLKE
KKESNEKAQKDLEKHVK
MKKSKWLALAGVALLGVGVLAACSSKSNTSGTTYGYVYSSDPETLDYITSNTGPTKSVVTNGVDGLMEADKYGNLVPSVA
EDWSVSKDGLTYTYKIRKGIKWYTSEGEEYANVTAKDFVTGLKHAADSKAGGIYLVQDSIAGLSDYLSGTNKDFSNVGVK
AIDDYTLQYTLKQPEPYWNSKTTYSLLFPVNEDFLKNKGKDFGKSTDPTSILYNGPFLLKSLTAKSSIELVKNEHYWDKK
NVHFDAIKFSYYDGSDQDALVRGFTDGAYNFARVFPTSSNYASVEKKYKDNIFYTAPGASTSAIGINIDRQSYKYTAKKT
DSEKSSTKKALLNKDFRQAINFAIDRKAYQSQINGKDGATLGVRNLFVPSDFVSAGDKTFGDLVTEKMSSYGDEWSGVNL
ADSQDGLYNAEKAKTEFAKAKDALQADGVQFPIHLDLPVNQSSKLNVAQVQSLKQTIEKSLGSENVVIDINQLSSDDLEN
ATLNAANAAAEDWDISNSVGWAPDYQDPSTYLDIFKTTSSENTKAFMGYDDPNNAAAAQVGLKDYDALLNSAASETSDLN
VRYDRYAQAQAWLEDSSLVIPLTVGNGAAPVISRLTPFTGASLQVGDKNSSNDYIKYVKPQEKVVTKKEYEQSREKWLKE
KKESNEKAQKDLEKHVK
Nucleotide
Download Length: 1974 bp
>NTDB_id=187856 BBD27_RS07180 WP_011681419.1 1347100..1349073(+) (amiA3) [Streptococcus thermophilus strain ND07]
ATGAAAAAAAGCAAATGGTTGGCCCTCGCGGGTGTAGCACTTCTAGGTGTTGGTGTGTTAGCGGCTTGTTCATCTAAATC
AAACACTAGCGGAACTACTTATGGTTACGTTTACAGTTCGGATCCAGAAACTTTGGATTATATTACATCAAATACGGGAC
CTACAAAATCTGTTGTGACAAATGGTGTAGATGGACTTATGGAAGCGGACAAATATGGTAATCTTGTTCCATCAGTAGCT
GAAGACTGGTCTGTGTCTAAAGATGGTCTTACTTATACCTATAAAATTCGTAAAGGGATCAAATGGTATACTTCTGAAGG
TGAAGAGTACGCTAATGTTACTGCTAAGGACTTTGTAACGGGTCTTAAACATGCTGCGGATTCCAAAGCAGGTGGTATCT
ATTTGGTTCAAGATTCTATTGCTGGATTGTCTGACTATCTCTCTGGTACCAATAAAGATTTCTCGAATGTGGGTGTCAAG
GCAATTGATGACTATACTTTGCAGTACACGCTTAAGCAACCAGAACCATACTGGAACTCTAAGACAACTTATAGTTTGCT
TTTCCCAGTAAATGAAGACTTCCTCAAGAATAAGGGAAAAGATTTTGGTAAATCAACAGACCCAACCTCTATCCTTTATA
ATGGACCTTTCCTTCTCAAATCTTTGACAGCTAAATCTTCAATTGAGTTGGTTAAGAATGAACATTATTGGGACAAGAAA
AATGTACACTTTGATGCCATCAAATTCTCATATTATGATGGTTCGGATCAAGATGCTCTAGTACGTGGTTTCACTGATGG
TGCTTATAATTTTGCTCGTGTCTTTCCAACAAGTTCAAACTATGCTTCTGTAGAAAAAAAATATAAAGATAATATTTTTT
ACACAGCACCAGGTGCGTCTACATCAGCTATTGGTATTAATATTGACCGTCAAAGTTACAAGTATACAGCCAAAAAGACG
GATTCTGAAAAATCATCAACCAAGAAAGCCCTTCTAAACAAGGACTTCCGTCAAGCAATTAACTTTGCCATTGACCGTAA
GGCCTATCAATCACAAATTAACGGTAAAGATGGTGCAACTCTAGGTGTTCGTAACCTCTTTGTGCCTTCTGATTTTGTGA
GTGCAGGTGATAAGACCTTCGGAGATCTTGTAACAGAGAAAATGTCTTCATATGGGGATGAATGGTCAGGTGTGAATCTT
GCTGATAGTCAAGATGGCCTCTACAATGCTGAAAAAGCTAAGACTGAGTTTGCCAAAGCTAAGGATGCTCTCCAAGCAGA
TGGTGTTCAATTCCCAATTCATTTGGACCTTCCAGTTAACCAAAGCTCTAAACTTAATGTTGCCCAAGTCCAATCTTTGA
AACAAACCATTGAAAAATCATTGGGTAGCGAAAATGTTGTTATAGATATTAACCAATTGTCATCTGATGATTTGGAAAAT
GCAACACTTAATGCAGCCAACGCAGCAGCAGAAGACTGGGATATTTCAAATAGTGTCGGTTGGGCGCCAGATTACCAAGA
TCCATCAACCTACCTTGATATCTTTAAGACAACTTCAAGTGAAAACACTAAGGCTTTCATGGGTTATGATGATCCAAATA
ATGCGGCAGCAGCCCAAGTGGGACTCAAAGACTATGATGCCTTGCTGAATTCTGCAGCTTCAGAAACAAGTGACCTTAAT
GTTCGTTACGATCGTTATGCTCAAGCTCAAGCATGGTTGGAGGACAGTTCGCTTGTGATTCCATTGACTGTTGGTAATGG
TGCGGCACCAGTTATCTCACGCTTGACACCGTTTACCGGTGCTAGCCTCCAGGTGGGTGATAAAAACTCATCAAACGACT
ACATCAAATATGTGAAACCACAAGAAAAAGTAGTTACTAAGAAAGAATATGAACAAAGTCGTGAAAAATGGCTTAAAGAA
AAGAAAGAATCTAACGAAAAAGCTCAAAAAGATCTTGAGAAACACGTTAAATAA
ATGAAAAAAAGCAAATGGTTGGCCCTCGCGGGTGTAGCACTTCTAGGTGTTGGTGTGTTAGCGGCTTGTTCATCTAAATC
AAACACTAGCGGAACTACTTATGGTTACGTTTACAGTTCGGATCCAGAAACTTTGGATTATATTACATCAAATACGGGAC
CTACAAAATCTGTTGTGACAAATGGTGTAGATGGACTTATGGAAGCGGACAAATATGGTAATCTTGTTCCATCAGTAGCT
GAAGACTGGTCTGTGTCTAAAGATGGTCTTACTTATACCTATAAAATTCGTAAAGGGATCAAATGGTATACTTCTGAAGG
TGAAGAGTACGCTAATGTTACTGCTAAGGACTTTGTAACGGGTCTTAAACATGCTGCGGATTCCAAAGCAGGTGGTATCT
ATTTGGTTCAAGATTCTATTGCTGGATTGTCTGACTATCTCTCTGGTACCAATAAAGATTTCTCGAATGTGGGTGTCAAG
GCAATTGATGACTATACTTTGCAGTACACGCTTAAGCAACCAGAACCATACTGGAACTCTAAGACAACTTATAGTTTGCT
TTTCCCAGTAAATGAAGACTTCCTCAAGAATAAGGGAAAAGATTTTGGTAAATCAACAGACCCAACCTCTATCCTTTATA
ATGGACCTTTCCTTCTCAAATCTTTGACAGCTAAATCTTCAATTGAGTTGGTTAAGAATGAACATTATTGGGACAAGAAA
AATGTACACTTTGATGCCATCAAATTCTCATATTATGATGGTTCGGATCAAGATGCTCTAGTACGTGGTTTCACTGATGG
TGCTTATAATTTTGCTCGTGTCTTTCCAACAAGTTCAAACTATGCTTCTGTAGAAAAAAAATATAAAGATAATATTTTTT
ACACAGCACCAGGTGCGTCTACATCAGCTATTGGTATTAATATTGACCGTCAAAGTTACAAGTATACAGCCAAAAAGACG
GATTCTGAAAAATCATCAACCAAGAAAGCCCTTCTAAACAAGGACTTCCGTCAAGCAATTAACTTTGCCATTGACCGTAA
GGCCTATCAATCACAAATTAACGGTAAAGATGGTGCAACTCTAGGTGTTCGTAACCTCTTTGTGCCTTCTGATTTTGTGA
GTGCAGGTGATAAGACCTTCGGAGATCTTGTAACAGAGAAAATGTCTTCATATGGGGATGAATGGTCAGGTGTGAATCTT
GCTGATAGTCAAGATGGCCTCTACAATGCTGAAAAAGCTAAGACTGAGTTTGCCAAAGCTAAGGATGCTCTCCAAGCAGA
TGGTGTTCAATTCCCAATTCATTTGGACCTTCCAGTTAACCAAAGCTCTAAACTTAATGTTGCCCAAGTCCAATCTTTGA
AACAAACCATTGAAAAATCATTGGGTAGCGAAAATGTTGTTATAGATATTAACCAATTGTCATCTGATGATTTGGAAAAT
GCAACACTTAATGCAGCCAACGCAGCAGCAGAAGACTGGGATATTTCAAATAGTGTCGGTTGGGCGCCAGATTACCAAGA
TCCATCAACCTACCTTGATATCTTTAAGACAACTTCAAGTGAAAACACTAAGGCTTTCATGGGTTATGATGATCCAAATA
ATGCGGCAGCAGCCCAAGTGGGACTCAAAGACTATGATGCCTTGCTGAATTCTGCAGCTTCAGAAACAAGTGACCTTAAT
GTTCGTTACGATCGTTATGCTCAAGCTCAAGCATGGTTGGAGGACAGTTCGCTTGTGATTCCATTGACTGTTGGTAATGG
TGCGGCACCAGTTATCTCACGCTTGACACCGTTTACCGGTGCTAGCCTCCAGGTGGGTGATAAAAACTCATCAAACGACT
ACATCAAATATGTGAAACCACAAGAAAAAGTAGTTACTAAGAAAGAATATGAACAAAGTCGTGAAAAATGGCTTAAAGAA
AAGAAAGAATCTAACGAAAAAGCTCAAAAAGATCTTGAGAAACACGTTAAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| amiA3 | Streptococcus thermophilus LMD-9 |
100 |
100 |
1 |
| amiA3 | Streptococcus thermophilus LMG 18311 |
98.478 |
100 |
0.985 |
| amiA | Streptococcus salivarius strain HSISS4 |
90.411 |
100 |
0.904 |