Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   B6R96_RS27075 Genome accession   NZ_CP020555
Coordinates   6034738..6035397 (+) Length   219 a.a.
NCBI ID   WP_203351662.1    Uniprot ID   -
Organism   Streptomyces sp. Sge12     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6029738..6040397
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B6R96_RS27055 (B6R96_27055) - 6030503..6031204 (-) 702 WP_030386467.1 transglycosylase SLT domain-containing protein -
  B6R96_RS27060 (B6R96_27060) - 6031501..6032562 (-) 1062 WP_107475749.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  B6R96_RS27065 (B6R96_27065) - 6032748..6033425 (-) 678 Protein_5321 SDR family oxidoreductase -
  B6R96_RS27070 (B6R96_27070) - 6033582..6034745 (+) 1164 WP_030386464.1 GAF domain-containing sensor histidine kinase -
  B6R96_RS27075 (B6R96_27075) vraR 6034738..6035397 (+) 660 WP_203351662.1 response regulator transcription factor Regulator
  B6R96_RS27080 (B6R96_27080) - 6035548..6035793 (+) 246 WP_030386462.1 chaplin -
  B6R96_RS27085 (B6R96_27085) - 6036084..6036866 (-) 783 WP_030386461.1 hypothetical protein -
  B6R96_RS27090 (B6R96_27090) - 6037015..6037809 (+) 795 WP_030386460.1 ABC transporter ATP-binding protein -
  B6R96_RS27095 (B6R96_27095) - 6037884..6038312 (+) 429 WP_030386459.1 NfeD family protein -
  B6R96_RS27100 (B6R96_27100) - 6038397..6039386 (+) 990 WP_052877039.1 SPFH domain-containing protein -
  B6R96_RS27105 (B6R96_27105) - 6039476..6040246 (+) 771 WP_081525278.1 sulfite exporter TauE/SafE family protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 23738.01 Da        Isoelectric Point: 5.1748

>NTDB_id=187631 B6R96_RS27075 WP_203351662.1 6034738..6035397(+) (vraR) [Streptomyces sp. Sge12]
MADSTGRSGGIRVLLVDDHQVVRRGLRTFLEVQEDIEVVGEASDGEEGVARAEELRPDVILMDIKMPGTDGIEALRRLRE
LTNPARVLIVTSFTEQRTVVPALRAGAAGYVYKDIDPEALAGAIRSVHAGHVLLQPEVAVALLSQDDQGSPAGRPGSLTD
REREVLGLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLSDRTQAALWAVRHGITE

Nucleotide


Download         Length: 660 bp        

>NTDB_id=187631 B6R96_RS27075 WP_203351662.1 6034738..6035397(+) (vraR) [Streptomyces sp. Sge12]
GTGGCTGACAGCACCGGCCGCAGCGGCGGCATTCGAGTCCTGCTGGTCGACGACCACCAGGTGGTCCGGCGGGGCCTGCG
CACCTTCCTGGAGGTCCAGGAGGACATCGAGGTGGTGGGGGAGGCCTCCGACGGCGAGGAGGGCGTCGCCCGTGCCGAGG
AGCTGCGGCCCGACGTGATCCTGATGGACATCAAGATGCCGGGCACGGACGGCATCGAAGCGCTGCGCAGGCTGCGCGAG
CTGACGAACCCGGCGCGGGTGCTGATCGTCACCAGCTTCACGGAGCAGCGGACCGTGGTCCCGGCCCTGCGGGCCGGCGC
GGCGGGATACGTCTACAAGGACATCGACCCCGAGGCACTGGCCGGGGCCATCCGCTCCGTGCACGCGGGCCACGTGCTGC
TCCAGCCGGAGGTGGCGGTGGCCCTGCTCTCCCAGGACGACCAGGGCTCCCCGGCGGGCCGGCCGGGCTCGCTGACCGAC
CGCGAACGCGAGGTCCTGGGCCTGATCGCCGACGGCCGCTCCAACCGGGAGATCGCCCGGGCCCTGGTCCTGTCCGAGAA
GACCGTCAAGACCCACGTGTCGAACATCCTGATGAAGTTGGACCTTTCCGACCGGACGCAGGCCGCATTGTGGGCGGTCA
GGCACGGAATCACCGAGTAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(157-212)

Response regulator receiver domain (Response_reg)

(13-124)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.976

95.434

0.429
  degU Bacillus subtilis subsp. subtilis str. 168

38.839

100

0.397
  letA Legionella pneumophila str. Paris

38.498

97.26

0.374
  letA Legionella pneumophila strain ERS1305867

38.498

97.26

0.374

Multiple sequence alignment