Detailed information    

insolico Bioinformatically predicted

Overview


Name   comEA   Type   Machinery gene
Locus tag   A0O31_RS05595 Genome accession   NZ_CP016312
Coordinates   1073094..1073402 (-) Length   102 a.a.
NCBI ID   WP_071677021.1    Uniprot ID   A0A1J0LTC7
Organism   Thermus brockianus strain GE-1     
Function   dsDNA binding (predicted from homology)   
DNA binding and uptake

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1064212..1074690 1073094..1073402 within 0


Gene organization within MGE regions


Location: 1064212..1074690
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A0O31_RS05560 (A0O31_01144) dnaN 1064212..1065330 (-) 1119 WP_071677015.1 DNA polymerase III subunit beta -
  A0O31_RS05565 (A0O31_01145) dnaA 1065632..1066945 (-) 1314 WP_071677016.1 chromosomal replication initiator protein DnaA -
  A0O31_RS05570 (A0O31_01146) mnmG 1066998..1068800 (+) 1803 WP_420855814.1 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG -
  A0O31_RS05575 rsmG 1068829..1069553 (+) 725 Protein_1088 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  A0O31_RS05580 (A0O31_01148) soj 1069547..1070296 (+) 750 WP_071677018.1 chromosome-partitioning ATPase Soj -
  A0O31_RS05585 (A0O31_01149) - 1070280..1071086 (+) 807 WP_071677019.1 ParB/RepB/Spo0J family partition protein -
  A0O31_RS05590 (A0O31_01150) comA/comEC 1071074..1073107 (-) 2034 WP_071677020.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  A0O31_RS05595 (A0O31_01151) comEA 1073094..1073402 (-) 309 WP_071677021.1 ComEA family DNA-binding protein Machinery gene
  A0O31_RS13050 (A0O31_01152) - 1073375..1073638 (-) 264 WP_237259051.1 hypothetical protein -
  A0O31_RS05605 (A0O31_01153) - 1074061..1074690 (+) 630 WP_071677930.1 glycerophosphodiester phosphodiesterase -

Sequence


Protein


Download         Length: 102 a.a.        Molecular weight: 11047.16 Da        Isoelectric Point: 9.8638

>NTDB_id=186786 A0O31_RS05595 WP_071677021.1 1073094..1073402(-) (comEA) [Thermus brockianus strain GE-1]
MVLGYLLAVALLALLSLWPKVAPSPKAVRVETYVQAAFTPPPPEPVSLNQASLEALEALPGVGPVLARRILEGRPYERVE
DLLKVKGIGPATLEKLRPYVRP

Nucleotide


Download         Length: 309 bp        

>NTDB_id=186786 A0O31_RS05595 WP_071677021.1 1073094..1073402(-) (comEA) [Thermus brockianus strain GE-1]
GTGGTTCTTGGCTACCTCCTGGCGGTAGCCCTCTTGGCCCTCCTCAGCCTCTGGCCCAAGGTGGCCCCAAGCCCCAAGGC
GGTGCGGGTGGAAACCTATGTCCAGGCCGCCTTCACCCCGCCACCGCCTGAGCCGGTGAGCCTGAACCAGGCGAGCCTCG
AGGCGCTGGAGGCCCTCCCCGGCGTGGGCCCGGTCCTGGCCCGGCGCATTCTGGAGGGGAGGCCGTACGAGCGGGTGGAA
GACCTTCTCAAGGTGAAGGGCATCGGCCCCGCCACCCTAGAGAAGCTCCGGCCGTATGTCCGCCCCTAG

Domains


Predicted by InterproScan.

(45-101)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A1J0LTC7

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Thermus thermophilus HB27

75.49

100

0.755

  comEA Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

51.389

70.588

0.363


Multiple sequence alignment