Detailed information NTG0186387

Bioinformatically predicted

Overview

• Name: pilC
• Type: Machinery gene
• Locus tag: A6B40_RS00440
• Genome accession: NZ_CP016226
• Coordinates: 94210..95406 (+)
• Length: 398 a.a.
• NCBI ID: WP_176671234.1
• Uniprot ID: -
• Organism: Mannheimia varigena strain 177
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 89210..100406

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6B40_RS00420 (A6B40_00420)	-	90480..90713 (+)	234	WP_025247569.1	YgjV family protein	-
A6B40_RS00425 (A6B40_00425)	radA	90767..92146 (-)	1380	WP_025247570.1	DNA repair protein RadA	-
A6B40_RS00430 (A6B40_00430)	pilA	92326..92805 (+)	480	WP_025217064.1	prepilin peptidase-dependent pilin	Machinery gene
A6B40_RS00435 (A6B40_00435)	pilB	92826..94217 (+)	1392	WP_176671233.1	GspE/PulE family protein	Machinery gene
A6B40_RS00440 (A6B40_00440)	pilC	94210..95406 (+)	1197	WP_176671234.1	type II secretion system F family protein	Machinery gene
A6B40_RS00445 (A6B40_00445)	-	95410..96066 (+)	657	WP_176671235.1	prepilin peptidase	-
A6B40_RS00450 (A6B40_00450)	coaE	96098..96733 (+)	636	WP_025247575.1	dephospho-CoA kinase	-
A6B40_RS00455 (A6B40_00455)	yacG	96715..96900 (+)	186	WP_176671236.1	DNA gyrase inhibitor YacG	-
A6B40_RS00460 (A6B40_00460)	holA	96901..97923 (-)	1023	WP_176671237.1	DNA polymerase III subunit delta	-
A6B40_RS00465 (A6B40_00465)	lptE	97963..98451 (-)	489	WP_112110826.1	LPS assembly lipoprotein LptE	-

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 45622.15 Da
• Isoelectric Point: 9.5186

>NTDB_id=186387 A6B40_RS00440 WP_176671234.1 94210..95406(+) (pilC) [Mannheimia varigena strain 177]
MVKIYEFHWKAVDRFQQKRKGRLLSSNREELENRLLTKGYQQIRISRNFVFSQNPKREEISQFLAQLALLVNSAVPLKQA
LVMILQNCRNIELHLWLSELIQLIESGYAFSQSLERLNKFIANQEIQLIKMGEQSGKLGLILTNLAESRLKSDKLAKKVK
KILFYPAIVLFISFSLSIGLLVFIVPQFAELYGTKEQALPLITEILFSLSQCLIEQKNLLFSLFLLAVIFFLFFAKRGNW
AAKLKISVLSKLPVFRQIIEQARIVFFSQNIALMLNAHIPLDVALKSFLSEKSDDPILQKEVEFMLNLLQQGYKFSQGIN
SNVFGLDMLQMIEIGEQSGNVAKMCSHISEMYQQKLDYQIDILSQLLEPMLMLLMGVIVGTIIVGLYLPIFDMGSLVE

Nucleotide

• Length: 1197 bp

>NTDB_id=186387 A6B40_RS00440 WP_176671234.1 94210..95406(+) (pilC) [Mannheimia varigena strain 177]
ATGGTTAAAATCTATGAGTTTCATTGGAAGGCGGTAGATCGTTTTCAACAAAAACGTAAGGGCAGATTATTATCTTCAAA
CAGAGAAGAGCTTGAAAATAGATTACTTACTAAAGGTTATCAGCAAATTCGCATTAGCCGAAACTTTGTGTTTTCACAAA
ACCCTAAAAGAGAAGAAATTAGTCAATTTCTCGCTCAGCTTGCTTTGTTGGTTAATTCTGCTGTGCCGTTAAAACAAGCC
TTAGTAATGATTTTACAAAACTGTCGAAATATTGAGCTTCATCTATGGCTAAGCGAGCTTATTCAACTCATTGAAAGTGG
TTATGCTTTTTCACAATCATTAGAACGGCTCAATAAATTTATCGCTAACCAAGAAATTCAACTAATTAAAATGGGCGAGC
AGAGCGGAAAACTCGGTTTGATTTTAACCAACTTGGCGGAGAGCAGACTTAAATCGGATAAACTGGCTAAAAAAGTCAAG
AAAATCCTGTTTTATCCAGCAATTGTACTGTTTATCTCATTCTCTCTTTCTATCGGACTTTTGGTATTCATCGTGCCACA
ATTTGCCGAACTTTACGGCACAAAAGAACAAGCCTTACCGCTGATTACTGAGATTTTATTTTCTCTTTCTCAATGTTTGA
TTGAACAGAAGAATCTTTTATTCAGTTTATTTTTACTAGCGGTTATTTTTTTCTTATTTTTTGCAAAAAGAGGGAATTGG
GCAGCGAAATTGAAAATCAGCGTATTGTCTAAGCTCCCTGTTTTTAGACAAATTATAGAGCAAGCTCGCATTGTCTTTTT
TAGCCAAAATATTGCGTTGATGTTGAATGCTCATATTCCATTAGATGTCGCATTAAAATCCTTTTTATCTGAAAAAAGTG
ATGACCCTATATTACAAAAAGAAGTTGAGTTTATGCTCAATCTCTTACAACAAGGCTATAAGTTTTCGCAAGGTATCAAC
TCAAATGTGTTTGGCTTAGATATGCTTCAGATGATTGAGATAGGCGAACAGAGCGGTAATGTTGCTAAAATGTGTTCGCA
TATTAGCGAGATGTATCAACAAAAACTGGATTATCAAATTGATATTCTCTCCCAATTATTAGAGCCAATGCTGATGCTAT
TAATGGGCGTAATTGTCGGCACTATTATTGTTGGGCTGTACTTGCCTATTTTCGATATGGGCTCATTGGTGGAGTAG

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (267-389)

• Type II secretion system (T2SS), protein F (T2SSF) (63-186)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilC	Glaesserella parasuis strain SC1401	56.11	100	0.565
pilC	Haemophilus influenzae Rd KW20	42.394	100	0.427
pilC	Haemophilus influenzae 86-028NP	41.397	100	0.417