Detailed information
Bioinformatically predicted
Overview
| Name | pilH | Type | Machinery gene |
| Locus tag | ASO12_RS02415 | Genome accession | NZ_CP016015 |
| Coordinates | 449131..449796 (+) | Length | 221 a.a. |
| NCBI ID | WP_047918678.1 | Uniprot ID | - |
| Organism | Neisseria gonorrhoeae strain 32867 | ||
| Function | type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 442130..488959 | 449131..449796 | within | 0 |
Gene organization within MGE regions
Location: 442130..488959
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ASO12_RS02380 (ASO12_02380) | - | 442130..443206 (-) | 1077 | WP_003687905.1 | sulfate/molybdate ABC transporter ATP-binding protein | - |
| ASO12_RS02385 (ASO12_02385) | cysW | 443203..444063 (-) | 861 | WP_003687906.1 | sulfate ABC transporter permease subunit CysW | - |
| ASO12_RS02390 (ASO12_02390) | cysT | 444252..445088 (-) | 837 | WP_003687907.1 | sulfate ABC transporter permease subunit CysT | - |
| ASO12_RS02395 (ASO12_02395) | - | 445269..445601 (+) | 333 | WP_003687908.1 | hypothetical protein | - |
| ASO12_RS02400 (ASO12_02400) | - | 445932..446441 (+) | 510 | WP_003687909.1 | isoprenylcysteine carboxyl methyltransferase family protein | - |
| ASO12_RS02405 (ASO12_02405) | - | 446673..447254 (-) | 582 | WP_047918049.1 | superoxide dismutase | - |
| ASO12_RS02410 (ASO12_02410) | dnaB | 447417..448823 (+) | 1407 | WP_003690896.1 | replicative DNA helicase | - |
| ASO12_RS02415 (ASO12_02415) | pilH | 449131..449796 (+) | 666 | WP_047918678.1 | GspH/FimT family pseudopilin | Machinery gene |
| ASO12_RS02420 (ASO12_02420) | pilV | 449828..450436 (+) | 609 | WP_003692820.1 | type IV pilus modification protein PilV | Machinery gene |
| ASO12_RS02425 (ASO12_02425) | pilJ | 450433..451377 (+) | 945 | WP_047916984.1 | PilW family protein | Machinery gene |
| ASO12_RS02430 (ASO12_02430) | pilK | 451356..451967 (+) | 612 | WP_047921729.1 | pilus assembly PilX family protein | Machinery gene |
| ASO12_RS02435 (ASO12_02435) | pilL | 451969..452442 (+) | 474 | WP_180364901.1 | PilX family type IV pilin | Machinery gene |
| ASO12_RS02440 (ASO12_02440) | - | 452512..452820 (-) | 309 | WP_010951048.1 | AzlD family protein | - |
| ASO12_RS13850 | - | 452817..453524 (-) | 708 | Protein_456 | AzlC family ABC transporter permease | - |
| ASO12_RS02450 (ASO12_02450) | dut | 453690..454142 (+) | 453 | WP_047918679.1 | dUTP diphosphatase | - |
| ASO12_RS02455 (ASO12_02455) | dapC | 454218..455405 (+) | 1188 | WP_047918680.1 | succinyldiaminopimelate transaminase | - |
| ASO12_RS02460 (ASO12_02460) | yaaA | 455716..456495 (+) | 780 | WP_047918681.1 | peroxide stress protein YaaA | - |
| ASO12_RS02475 (ASO12_02475) | - | 457025..458217 (+) | 1193 | Protein_460 | tyrosine-type recombinase/integrase | - |
| ASO12_RS02485 (ASO12_02485) | - | 458573..458842 (-) | 270 | WP_003687928.1 | hypothetical protein | - |
| ASO12_RS02490 (ASO12_02490) | - | 459037..459720 (-) | 684 | WP_003687929.1 | DUF2786 domain-containing protein | - |
| ASO12_RS14795 | - | 460000..460266 (-) | 267 | Protein_463 | hypothetical protein | - |
| ASO12_RS02500 (ASO12_02500) | - | 460377..460592 (-) | 216 | WP_003691538.1 | hypothetical protein | - |
| ASO12_RS02505 (ASO12_02505) | - | 460644..461135 (-) | 492 | WP_003691537.1 | siphovirus Gp157 family protein | - |
| ASO12_RS02510 (ASO12_02510) | - | 461132..461314 (-) | 183 | WP_003691535.1 | hypothetical protein | - |
| ASO12_RS02515 (ASO12_02515) | - | 461454..462140 (-) | 687 | WP_042758540.1 | phage replication initiation protein, NGO0469 family | - |
| ASO12_RS02520 (ASO12_02520) | - | 462209..462370 (-) | 162 | WP_003691530.1 | hypothetical protein | - |
| ASO12_RS02525 (ASO12_02525) | - | 462367..462645 (-) | 279 | WP_047921579.1 | NGO1622 family putative holin | - |
| ASO12_RS02530 (ASO12_02530) | - | 462799..463131 (-) | 333 | WP_003695500.1 | hypothetical protein | - |
| ASO12_RS02535 (ASO12_02535) | - | 463272..463559 (-) | 288 | WP_050171272.1 | hypothetical protein | - |
| ASO12_RS02540 (ASO12_02540) | - | 463556..464032 (-) | 477 | WP_002255718.1 | DUF6948 domain-containing protein | - |
| ASO12_RS02545 (ASO12_02545) | - | 464065..464265 (-) | 201 | WP_048654497.1 | hypothetical protein | - |
| ASO12_RS02550 (ASO12_02550) | - | 464592..465152 (-) | 561 | WP_002231760.1 | hypothetical protein | - |
| ASO12_RS02555 (ASO12_02555) | - | 465152..465850 (-) | 699 | WP_002255715.1 | S24 family peptidase | - |
| ASO12_RS12350 | - | 465964..466194 (+) | 231 | WP_014580259.1 | transcriptional regulator | - |
| ASO12_RS02560 (ASO12_02560) | - | 466297..467196 (+) | 900 | WP_050162082.1 | replication protein | - |
| ASO12_RS02565 (ASO12_02565) | - | 467208..467987 (+) | 780 | WP_047917947.1 | ATP-binding protein | - |
| ASO12_RS02570 (ASO12_02570) | - | 468057..468287 (+) | 231 | WP_003701140.1 | hypothetical protein | - |
| ASO12_RS02575 (ASO12_02575) | - | 468301..468795 (+) | 495 | WP_041421248.1 | DUF3310 domain-containing protein | - |
| ASO12_RS02580 (ASO12_02580) | - | 468972..469121 (+) | 150 | WP_003689110.1 | hypothetical protein | - |
| ASO12_RS14800 | - | 469150..469431 (+) | 282 | WP_003689109.1 | hypothetical protein | - |
| ASO12_RS02585 (ASO12_02585) | - | 469422..469859 (+) | 438 | WP_082280641.1 | RusA family crossover junction endodeoxyribonuclease | - |
| ASO12_RS02590 (ASO12_02590) | - | 469852..470157 (+) | 306 | WP_003687981.1 | nuclease domain-containing protein | - |
| ASO12_RS02595 (ASO12_02595) | - | 470154..470537 (+) | 384 | WP_003687982.1 | recombination protein NinB | - |
| ASO12_RS02600 (ASO12_02600) | - | 470528..471046 (+) | 519 | WP_003687984.1 | HNH endonuclease | - |
| ASO12_RS02605 (ASO12_02605) | - | 471112..471534 (+) | 423 | WP_003704254.1 | hypothetical protein | - |
| ASO12_RS02610 (ASO12_02610) | - | 471534..471776 (+) | 243 | WP_003706439.1 | hypothetical protein | - |
| ASO12_RS02615 (ASO12_02615) | - | 471831..472073 (+) | 243 | WP_003687989.1 | hypothetical protein | - |
| ASO12_RS02620 (ASO12_02620) | - | 472054..473328 (+) | 1275 | WP_003687990.1 | PBSX family phage terminase large subunit | - |
| ASO12_RS02625 (ASO12_02625) | - | 473313..475580 (+) | 2268 | WP_003687991.1 | hypothetical protein | - |
| ASO12_RS02630 (ASO12_02630) | - | 475817..477013 (+) | 1197 | WP_003687992.1 | hypothetical protein | - |
| ASO12_RS02635 (ASO12_02635) | - | 477010..484311 (+) | 7302 | WP_047919510.1 | PLxRFG domain-containing protein | - |
| ASO12_RS02645 (ASO12_02645) | - | 484937..486229 (+) | 1293 | WP_003687995.1 | DUF4043 family protein | - |
| ASO12_RS02650 (ASO12_02650) | - | 486284..486757 (+) | 474 | WP_003687996.1 | hypothetical protein | - |
| ASO12_RS02655 (ASO12_02655) | - | 486763..487248 (+) | 486 | WP_003687997.1 | hypothetical protein | - |
| ASO12_RS02660 (ASO12_02660) | - | 487245..487919 (+) | 675 | WP_003687998.1 | hypothetical protein | - |
| ASO12_RS02665 (ASO12_02665) | - | 487910..488071 (+) | 162 | WP_003687999.1 | hypothetical protein | - |
| ASO12_RS02670 (ASO12_02670) | - | 488108..488959 (-) | 852 | WP_050162101.1 | Bro-N domain-containing protein | - |
Sequence
Protein
Download Length: 221 a.a. Molecular weight: 24613.96 Da Isoelectric Point: 8.6140
>NTDB_id=185124 ASO12_RS02415 WP_047918678.1 449131..449796(+) (pilH) [Neisseria gonorrhoeae strain 32867]
MCTRKQQGFTLTELLIVMAIAAIMATIALPNMSGWIASRRIASHAEQIANLLRFSRGEAVRLNLPVYICPAQVKKDGTVD
NQCDFGKKEQGMLAFGDKNDNKAYDGDAADVFLRNVVLNDDIKDKRINYTFNHIAFGSSQPTADRVVWTFNQNGTFGYTK
DQHLASTSSFFYSDGYIQIVLTDARAVSDADRKFRSAVVLIDSSGRVEVCRKNDTRAVCKH
MCTRKQQGFTLTELLIVMAIAAIMATIALPNMSGWIASRRIASHAEQIANLLRFSRGEAVRLNLPVYICPAQVKKDGTVD
NQCDFGKKEQGMLAFGDKNDNKAYDGDAADVFLRNVVLNDDIKDKRINYTFNHIAFGSSQPTADRVVWTFNQNGTFGYTK
DQHLASTSSFFYSDGYIQIVLTDARAVSDADRKFRSAVVLIDSSGRVEVCRKNDTRAVCKH
Nucleotide
Download Length: 666 bp
>NTDB_id=185124 ASO12_RS02415 WP_047918678.1 449131..449796(+) (pilH) [Neisseria gonorrhoeae strain 32867]
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGCCATTGCAGCCATTATGGCGACGAT
AGCCCTCCCCAATATGAGTGGGTGGATTGCATCACGCCGCATTGCCAGTCACGCGGAGCAGATTGCCAACCTTTTGCGTT
TCTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGCCCAAGTTAAAAAAGACGGTACGGTCGAC
AACCAATGCGACTTCGGTAAGAAGGAACAGGGGATGTTGGCTTTCGGCGACAAAAACGACAATAAGGCATATGACGGCGA
TGCTGCGGATGTTTTTCTCCGTAACGTGGTATTGAATGATGATATCAAGGATAAGCGGATTAATTACACCTTCAATCATA
TCGCTTTCGGTTCGTCTCAGCCGACCGCCGACCGTGTAGTTTGGACATTCAATCAAAACGGGACGTTCGGTTATACGAAA
GACCAGCATCTTGCAAGCACATCCAGCTTTTTTTATTCCGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGT
TTCAGATGCCGATAGGAAATTCCGTTCGGCGGTGGTTTTGATTGACAGCAGCGGCAGGGTCGAAGTTTGTCGTAAAAACG
ATACGCGCGCCGTATGCAAACATTAA
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGCCATTGCAGCCATTATGGCGACGAT
AGCCCTCCCCAATATGAGTGGGTGGATTGCATCACGCCGCATTGCCAGTCACGCGGAGCAGATTGCCAACCTTTTGCGTT
TCTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGCCCAAGTTAAAAAAGACGGTACGGTCGAC
AACCAATGCGACTTCGGTAAGAAGGAACAGGGGATGTTGGCTTTCGGCGACAAAAACGACAATAAGGCATATGACGGCGA
TGCTGCGGATGTTTTTCTCCGTAACGTGGTATTGAATGATGATATCAAGGATAAGCGGATTAATTACACCTTCAATCATA
TCGCTTTCGGTTCGTCTCAGCCGACCGCCGACCGTGTAGTTTGGACATTCAATCAAAACGGGACGTTCGGTTATACGAAA
GACCAGCATCTTGCAAGCACATCCAGCTTTTTTTATTCCGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGT
TTCAGATGCCGATAGGAAATTCCGTTCGGCGGTGGTTTTGATTGACAGCAGCGGCAGGGTCGAAGTTTGTCGTAAAAACG
ATACGCGCGCCGTATGCAAACATTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilH | Neisseria gonorrhoeae MS11 |
86.878 |
100 |
0.869 |