Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | A7E59_RS00445 | Genome accession | NZ_CP015552 |
| Coordinates | 98642..100267 (-) | Length | 541 a.a. |
| NCBI ID | WP_046099800.1 | Uniprot ID | A0AAJ0JPE0 |
| Organism | Staphylococcus carnosus strain TMW 2.1538 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 44568..101638 | 98642..100267 | within | 0 |
Gene organization within MGE regions
Location: 44568..101638
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| A7E59_RS00200 (A7E59_00195) | ccrA | 46050..47399 (-) | 1350 | WP_046099890.1 | recombinase family protein | Machinery gene |
| A7E59_RS00205 (A7E59_00200) | - | 47591..47866 (-) | 276 | WP_046099761.1 | hypothetical protein | - |
| A7E59_RS00210 (A7E59_00205) | - | 47935..49722 (-) | 1788 | WP_046099762.1 | DUF927 domain-containing protein | - |
| A7E59_RS00215 (A7E59_00210) | - | 49722..50015 (-) | 294 | WP_046099763.1 | DUF1413 domain-containing protein | - |
| A7E59_RS00220 (A7E59_00215) | - | 50152..51201 (+) | 1050 | WP_046099764.1 | hypothetical protein | - |
| A7E59_RS00225 (A7E59_00220) | - | 51240..52541 (+) | 1302 | WP_046099765.1 | ATP-binding protein | - |
| A7E59_RS00230 (A7E59_00225) | - | 52953..54398 (+) | 1446 | WP_082080567.1 | four-carbon acid sugar kinase family protein | - |
| A7E59_RS00235 (A7E59_00230) | - | 54417..55778 (+) | 1362 | WP_046099766.1 | gluconate:H+ symporter | - |
| A7E59_RS00245 (A7E59_00235) | - | 56671..57408 (+) | 738 | WP_046099892.1 | GntR family transcriptional regulator | - |
| A7E59_RS00250 (A7E59_00240) | deoD | 57751..58458 (+) | 708 | WP_046099767.1 | purine-nucleoside phosphorylase | - |
| A7E59_RS00255 (A7E59_00245) | - | 58471..59826 (+) | 1356 | WP_046099768.1 | tetracycline resistance MFS efflux pump | - |
| A7E59_RS00260 (A7E59_00250) | deoC | 59840..60502 (+) | 663 | WP_046099769.1 | deoxyribose-phosphate aldolase | - |
| A7E59_RS00265 (A7E59_00255) | deoB | 60531..61709 (+) | 1179 | WP_046099770.1 | phosphopentomutase | - |
| A7E59_RS00270 (A7E59_00260) | - | 61755..61883 (-) | 129 | Protein_50 | NAD-dependent protein deacylase | - |
| A7E59_RS00275 (A7E59_00265) | ccrB | 62285..63913 (-) | 1629 | WP_046099772.1 | recombinase family protein | Machinery gene |
| A7E59_RS00280 (A7E59_00270) | ccrA | 63934..65283 (-) | 1350 | WP_046099773.1 | recombinase family protein | Machinery gene |
| A7E59_RS00285 (A7E59_00275) | - | 65669..66442 (+) | 774 | WP_046099774.1 | acetoin reductase | - |
| A7E59_RS00290 (A7E59_00280) | - | 66645..67937 (+) | 1293 | WP_046099775.1 | NtaA/DmoA family FMN-dependent monooxygenase | - |
| A7E59_RS00295 (A7E59_00290) | - | 68735..69586 (+) | 852 | WP_046099776.1 | hypothetical protein | - |
| A7E59_RS00300 (A7E59_00295) | - | 69616..71625 (+) | 2010 | WP_046099777.1 | hypothetical protein | - |
| A7E59_RS00305 (A7E59_00300) | - | 71823..72932 (+) | 1110 | WP_046099778.1 | DNA polymerase | - |
| A7E59_RS00310 (A7E59_00305) | - | 72925..73293 (+) | 369 | WP_046099779.1 | hypothetical protein | - |
| A7E59_RS00315 (A7E59_00310) | - | 73293..74936 (+) | 1644 | WP_046099780.1 | DUF5906 domain-containing protein | - |
| A7E59_RS00320 (A7E59_00315) | - | 75161..76837 (+) | 1677 | WP_046099781.1 | recombinase family protein | - |
| A7E59_RS00325 (A7E59_00320) | - | 76943..77281 (+) | 339 | WP_037576898.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| A7E59_RS00330 (A7E59_00325) | - | 77377..77688 (+) | 312 | WP_046099782.1 | DUF960 family protein | - |
| A7E59_RS00335 (A7E59_00330) | - | 77703..78209 (+) | 507 | WP_046099783.1 | DUF1643 domain-containing protein | - |
| A7E59_RS00340 (A7E59_00335) | - | 78237..78683 (+) | 447 | WP_046099784.1 | JAB domain-containing protein | - |
| A7E59_RS00345 (A7E59_00340) | - | 78853..79725 (+) | 873 | WP_046099785.1 | HTH domain-containing protein | - |
| A7E59_RS00350 (A7E59_00345) | - | 79782..80072 (+) | 291 | WP_046099786.1 | hypothetical protein | - |
| A7E59_RS00355 (A7E59_00350) | - | 80088..80414 (+) | 327 | WP_235318575.1 | hypothetical protein | - |
| A7E59_RS00360 | - | 80420..80578 (+) | 159 | WP_235318576.1 | hypothetical protein | - |
| A7E59_RS00365 (A7E59_00355) | - | 80717..81280 (+) | 564 | WP_046099787.1 | hypothetical protein | - |
| A7E59_RS00370 (A7E59_00360) | - | 81300..81845 (+) | 546 | WP_046099788.1 | hypothetical protein | - |
| A7E59_RS00375 (A7E59_00365) | galU | 82138..83005 (+) | 868 | Protein_71 | UTP--glucose-1-phosphate uridylyltransferase GalU | - |
| A7E59_RS00380 (A7E59_00370) | - | 83264..84385 (+) | 1122 | WP_046099789.1 | glycosyltransferase family 2 protein | - |
| A7E59_RS00385 (A7E59_00375) | - | 84385..86412 (+) | 2028 | WP_046099790.1 | CDP-glycerol--glycerophosphate glycerophosphotransferase | - |
| A7E59_RS00390 (A7E59_00380) | - | 86422..88059 (+) | 1638 | WP_052719452.1 | DUF6270 domain-containing protein | - |
| A7E59_RS00395 (A7E59_00385) | - | 88279..89595 (+) | 1317 | WP_046099791.1 | glycosyltransferase family 2 protein | - |
| A7E59_RS00400 (A7E59_00390) | - | 90069..92861 (+) | 2793 | WP_046099792.1 | type I restriction endonuclease subunit R | - |
| A7E59_RS00405 (A7E59_00395) | - | 92951..93532 (+) | 582 | WP_046099793.1 | restriction endonuclease subunit S | - |
| A7E59_RS00410 (A7E59_00400) | - | 93533..95089 (+) | 1557 | WP_046099794.1 | type I restriction-modification system subunit M | - |
| A7E59_RS00415 (A7E59_00405) | - | 95082..96308 (+) | 1227 | WP_046099795.1 | restriction endonuclease subunit S | - |
| A7E59_RS00420 (A7E59_00410) | - | 96359..96607 (+) | 249 | WP_046099796.1 | hypothetical protein | - |
| A7E59_RS00425 (A7E59_00415) | - | 96672..96893 (-) | 222 | WP_046099797.1 | hypothetical protein | - |
| A7E59_RS00430 (A7E59_00420) | - | 96908..97408 (-) | 501 | WP_046099798.1 | DUF1643 domain-containing protein | - |
| A7E59_RS00435 (A7E59_00425) | - | 97422..97733 (-) | 312 | WP_046099799.1 | DUF960 family protein | - |
| A7E59_RS00440 (A7E59_00430) | - | 97829..98167 (-) | 339 | Protein_84 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| A7E59_RS00445 (A7E59_00435) | ccrB | 98642..100267 (-) | 1626 | WP_046099800.1 | recombinase family protein | Machinery gene |
| A7E59_RS00450 (A7E59_00440) | ccrA | 100289..101638 (-) | 1350 | WP_046099801.1 | recombinase family protein | Machinery gene |
Sequence
Protein
Download Length: 541 a.a. Molecular weight: 62149.16 Da Isoelectric Point: 9.8140
>NTDB_id=180589 A7E59_RS00445 WP_046099800.1 98642..100267(-) (ccrB) [Staphylococcus carnosus strain TMW 2.1538]
MSEMKKKRIGGYIRVSTEKQVMGYSIEGQITQIEQYCQFNGYELVDIYADRGISGKSMNRPELQRMLNDAKNGKLDCVMV
YKTNRLARNTSDLLTIVEELHRQNVEFFSLSERMEVKNSTGKLMLQILASFSEFERNKILENIYNGQHQRALEGYYQGNL
PLGYNNIPDNKKELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGNPFSISAVTYILSNPFYIGKIQFAKY
KDWNDKRRKGLNDKPVIAEGKHTPIISQSLWDKVQARKKQVSEKPQVHGKGTNILTGLISCPQCSASMSASTTVNTLKDG
TKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVLKQVVERVNQENHVDVAALNHDIAYKQQQFDE
INTKLKNLIQTIEDNPDLTSALKPTIHQYETQLNDITNQMNQLKHQQNQEKPSYDTKQIAALLQQIFQNIESMDKAQLKA
LYLTVIDRIDIRKNGSHKKQFFVTLKLNNEIIKQLFNNTSLDEVLLSTSSLFLPQTLFLQI
MSEMKKKRIGGYIRVSTEKQVMGYSIEGQITQIEQYCQFNGYELVDIYADRGISGKSMNRPELQRMLNDAKNGKLDCVMV
YKTNRLARNTSDLLTIVEELHRQNVEFFSLSERMEVKNSTGKLMLQILASFSEFERNKILENIYNGQHQRALEGYYQGNL
PLGYNNIPDNKKELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGNPFSISAVTYILSNPFYIGKIQFAKY
KDWNDKRRKGLNDKPVIAEGKHTPIISQSLWDKVQARKKQVSEKPQVHGKGTNILTGLISCPQCSASMSASTTVNTLKDG
TKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVLKQVVERVNQENHVDVAALNHDIAYKQQQFDE
INTKLKNLIQTIEDNPDLTSALKPTIHQYETQLNDITNQMNQLKHQQNQEKPSYDTKQIAALLQQIFQNIESMDKAQLKA
LYLTVIDRIDIRKNGSHKKQFFVTLKLNNEIIKQLFNNTSLDEVLLSTSSLFLPQTLFLQI
Nucleotide
Download Length: 1626 bp
>NTDB_id=180589 A7E59_RS00445 WP_046099800.1 98642..100267(-) (ccrB) [Staphylococcus carnosus strain TMW 2.1538]
ATGAGTGAAATGAAGAAGAAGAGAATCGGAGGGTACATCCGCGTATCCACTGAAAAACAGGTAATGGGCTATAGCATCGA
GGGGCAAATTACACAAATAGAGCAATATTGCCAATTTAACGGCTATGAACTCGTTGATATATATGCAGATCGGGGTATAT
CAGGAAAATCTATGAACCGTCCTGAATTACAGCGCATGTTAAATGATGCTAAAAATGGAAAATTAGACTGTGTTATGGTT
TATAAAACAAATCGTTTGGCACGTAATACTTCCGATTTACTTACAATCGTCGAAGAACTTCATCGCCAAAATGTTGAATT
TTTTAGCTTGTCTGAACGCATGGAAGTCAAAAATTCAACAGGCAAGTTAATGCTCCAAATACTTGCAAGTTTTTCCGAAT
TTGAAAGAAATAAAATTTTAGAGAATATTTACAACGGTCAACATCAAAGAGCTTTAGAGGGCTATTATCAAGGCAATCTT
CCATTAGGATACAATAACATACCTGATAATAAAAAAGAATTAATGATTAATCAACATGAAGCTAACATCGTTAAATATAT
CTTTGAATCTTATGCCAAAGGTCATGGCTATCGTAAAATAGCCAATGCACTCAATCATAAAGGTTATGTCACTAAGAAAG
GCAATCCATTTAGTATTTCAGCTGTTACTTATATTCTCTCAAACCCATTCTATATTGGTAAAATTCAATTCGCGAAATAC
AAAGATTGGAATGATAAACGTCGTAAAGGCTTGAATGATAAGCCAGTAATCGCCGAAGGCAAACACACCCCTATTATTAG
CCAATCATTATGGGATAAAGTCCAAGCACGTAAAAAACAAGTAAGTGAAAAACCACAAGTCCATGGTAAAGGAACCAATA
TTTTAACTGGATTAATTTCGTGTCCACAATGTTCTGCTTCAATGTCTGCGAGCACAACAGTTAATACACTTAAAGATGGA
ACTAAGAAACGCATTCGCTATTATTCTTGTAGTAACTTTCGCAACAAAGGATCAAAGGTATGTTCGGCCAATAGTGTTAG
AGCCGATGTCATTGAAAAATATGTTATGGACCAAATACTTGAAATTGTCAAAAGTGATAAAGTTCTCAAACAAGTTGTCG
AACGCGTCAATCAAGAGAATCATGTAGATGTAGCAGCACTCAACCATGATATTGCTTATAAACAACAACAATTTGATGAA
ATTAACACTAAACTTAAAAATCTAATTCAAACCATCGAAGACAATCCAGACTTAACATCTGCACTCAAACCAACCATTCA
TCAATATGAAACACAACTGAATGATATCACAAACCAAATGAATCAACTCAAGCACCAACAAAATCAAGAGAAACCATCTT
ATGATACGAAACAGATCGCTGCCCTATTACAACAAATATTTCAAAACATAGAATCAATGGATAAAGCACAACTCAAAGCA
TTATACCTTACGGTCATTGACCGTATTGATATTCGTAAAAATGGAAGTCATAAAAAACAATTCTTTGTCACACTCAAGCT
CAATAATGAGATTATTAAACAACTTTTCAATAATACCTCTCTCGACGAAGTGCTCCTCAGCACTTCGTCTTTATTTTTGC
CTCAAACGCTCTTTCTTCAAATCTAA
ATGAGTGAAATGAAGAAGAAGAGAATCGGAGGGTACATCCGCGTATCCACTGAAAAACAGGTAATGGGCTATAGCATCGA
GGGGCAAATTACACAAATAGAGCAATATTGCCAATTTAACGGCTATGAACTCGTTGATATATATGCAGATCGGGGTATAT
CAGGAAAATCTATGAACCGTCCTGAATTACAGCGCATGTTAAATGATGCTAAAAATGGAAAATTAGACTGTGTTATGGTT
TATAAAACAAATCGTTTGGCACGTAATACTTCCGATTTACTTACAATCGTCGAAGAACTTCATCGCCAAAATGTTGAATT
TTTTAGCTTGTCTGAACGCATGGAAGTCAAAAATTCAACAGGCAAGTTAATGCTCCAAATACTTGCAAGTTTTTCCGAAT
TTGAAAGAAATAAAATTTTAGAGAATATTTACAACGGTCAACATCAAAGAGCTTTAGAGGGCTATTATCAAGGCAATCTT
CCATTAGGATACAATAACATACCTGATAATAAAAAAGAATTAATGATTAATCAACATGAAGCTAACATCGTTAAATATAT
CTTTGAATCTTATGCCAAAGGTCATGGCTATCGTAAAATAGCCAATGCACTCAATCATAAAGGTTATGTCACTAAGAAAG
GCAATCCATTTAGTATTTCAGCTGTTACTTATATTCTCTCAAACCCATTCTATATTGGTAAAATTCAATTCGCGAAATAC
AAAGATTGGAATGATAAACGTCGTAAAGGCTTGAATGATAAGCCAGTAATCGCCGAAGGCAAACACACCCCTATTATTAG
CCAATCATTATGGGATAAAGTCCAAGCACGTAAAAAACAAGTAAGTGAAAAACCACAAGTCCATGGTAAAGGAACCAATA
TTTTAACTGGATTAATTTCGTGTCCACAATGTTCTGCTTCAATGTCTGCGAGCACAACAGTTAATACACTTAAAGATGGA
ACTAAGAAACGCATTCGCTATTATTCTTGTAGTAACTTTCGCAACAAAGGATCAAAGGTATGTTCGGCCAATAGTGTTAG
AGCCGATGTCATTGAAAAATATGTTATGGACCAAATACTTGAAATTGTCAAAAGTGATAAAGTTCTCAAACAAGTTGTCG
AACGCGTCAATCAAGAGAATCATGTAGATGTAGCAGCACTCAACCATGATATTGCTTATAAACAACAACAATTTGATGAA
ATTAACACTAAACTTAAAAATCTAATTCAAACCATCGAAGACAATCCAGACTTAACATCTGCACTCAAACCAACCATTCA
TCAATATGAAACACAACTGAATGATATCACAAACCAAATGAATCAACTCAAGCACCAACAAAATCAAGAGAAACCATCTT
ATGATACGAAACAGATCGCTGCCCTATTACAACAAATATTTCAAAACATAGAATCAATGGATAAAGCACAACTCAAAGCA
TTATACCTTACGGTCATTGACCGTATTGATATTCGTAAAAATGGAAGTCATAAAAAACAATTCTTTGTCACACTCAAGCT
CAATAATGAGATTATTAAACAACTTTTCAATAATACCTCTCTCGACGAAGTGCTCCTCAGCACTTCGTCTTTATTTTTGC
CTCAAACGCTCTTTCTTCAAATCTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
78.598 |
100 |
0.787 |