Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   A6042_RS07680 Genome accession   NZ_CP015430
Coordinates   1589099..1590292 (+) Length   397 a.a.
NCBI ID   WP_064081941.1    Uniprot ID   -
Organism   [Haemophilus] ducreyi strain GHA2     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1584099..1595292
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6042_RS07655 (A6042_07655) - 1584801..1585286 (+) 486 WP_064081945.1 dihydrofolate reductase -
  A6042_RS07660 (A6042_07660) - 1585408..1585623 (+) 216 WP_010945033.1 YgjV family protein -
  A6042_RS07665 (A6042_07665) radA 1585690..1587069 (-) 1380 WP_064081944.1 DNA repair protein RadA -
  A6042_RS07670 (A6042_07670) pilA 1587263..1587709 (+) 447 WP_064081943.1 pilin Machinery gene
  A6042_RS07675 (A6042_07675) pilB 1587721..1589115 (+) 1395 WP_064081942.1 GspE/PulE family protein Machinery gene
  A6042_RS07680 (A6042_07680) pilC 1589099..1590292 (+) 1194 WP_064081941.1 type II secretion system F family protein Machinery gene
  A6042_RS07895 (A6042_07685) - 1590292..1590561 (+) 270 WP_078179334.1 hypothetical protein -
  A6042_RS07900 (A6042_07690) - 1590578..1590937 (+) 360 WP_327216412.1 prepilin peptidase -
  A6042_RS07690 (A6042_07695) coaE 1590955..1591572 (+) 618 WP_064081940.1 dephospho-CoA kinase -
  A6042_RS07695 (A6042_07700) yacG 1591575..1591763 (+) 189 WP_064081939.1 DNA gyrase inhibitor YacG -
  A6042_RS07700 (A6042_07705) holA 1591797..1592822 (-) 1026 WP_064083324.1 DNA polymerase III subunit delta -
  A6042_RS07705 (A6042_07710) lptE 1592828..1593325 (-) 498 WP_064081937.1 LPS assembly lipoprotein LptE -

Sequence

Protein


Download         Length: 397 a.a.        Molecular weight: 45709.40 Da        Isoelectric Point: 10.1709

>NTDB_id=179566 A6042_RS07680 WP_064081941.1 1589099..1590292(+) (pilC) [[Haemophilus] ducreyi strain GHA2]
MLKIYEFHWRAFNRFNQRQKGKSLAKSHDELEQRLLAKGYSNIHIQRDFILVRKPKSEQITQLINQLAMLLNASVPLKQS
LVMVLENVHNIKLYLWLYEIITLLEAGHTFSASLTKMNVYLTKQEIQLIKMGEQSGRLAIMLDNIAKVRTQSQKLANKVK
KIMFYPAIILAVSISVLIGLLLFIVPQFEDLYRNKDQSLPFITQLLFQLSNFLQQYAFILFIGGLFSGIVSYFLAKKRLF
WRTLRSRLLNHMPGFQQIIKDARIIFFSQNLALMLNAHIHLDATLKAFLSEHRQDPVLHQEILSILSLLKQGYKFSEGLN
PTVFTSQVVQMMAIGEQSGNLAKMCMCISQLYQQKLDYQIDLFAQLLEPVLMLVIGIIVGTILIGIYLPIFDMGALV

Nucleotide


Download         Length: 1194 bp        

>NTDB_id=179566 A6042_RS07680 WP_064081941.1 1589099..1590292(+) (pilC) [[Haemophilus] ducreyi strain GHA2]
ATGCTGAAAATATATGAATTTCATTGGCGGGCTTTTAATCGTTTTAATCAACGGCAAAAAGGTAAATCTCTGGCCAAAAG
TCACGATGAATTAGAACAACGGCTATTAGCTAAAGGCTATTCAAATATCCATATTCAACGTGATTTTATTTTAGTTAGGA
AACCCAAAAGCGAACAAATCACTCAATTAATTAATCAGTTAGCTATGTTATTGAATGCCTCGGTTCCATTAAAACAATCG
CTGGTGATGGTATTAGAAAACGTACATAATATTAAATTATATTTATGGTTATATGAAATTATTACGCTGTTAGAAGCGGG
GCATACTTTTTCAGCCAGTCTCACTAAAATGAACGTTTATTTGACTAAGCAAGAAATTCAGTTAATTAAGATGGGAGAAC
AGAGTGGGCGTTTAGCCATTATGCTAGATAACATTGCAAAAGTACGTACTCAATCACAGAAATTAGCTAATAAAGTAAAG
AAAATTATGTTTTATCCGGCGATTATTTTAGCCGTATCAATTAGTGTATTAATTGGATTGTTATTATTTATTGTGCCTCA
ATTTGAAGATCTTTATCGTAACAAAGATCAGTCACTGCCTTTTATTACCCAATTATTATTTCAGTTATCGAATTTTCTTC
AACAATATGCATTTATTTTATTCATCGGCGGCCTATTTAGCGGTATTGTTAGCTATTTTTTAGCGAAAAAGAGGCTTTTT
TGGCGTACCTTAAGATCGCGTTTATTAAATCATATGCCAGGGTTTCAGCAAATTATTAAAGATGCTCGAATTATTTTCTT
TAGTCAAAATCTTGCGTTAATGCTTAATGCACATATTCATTTAGATGCAACGTTAAAAGCATTTTTATCAGAACATCGCC
AAGATCCGGTATTACATCAGGAGATTTTGAGTATATTAAGTTTATTAAAGCAAGGTTATAAATTCTCTGAGGGGCTTAAT
CCAACCGTATTTACTAGCCAAGTAGTACAAATGATGGCAATTGGCGAACAAAGTGGTAATTTGGCTAAAATGTGTATGTG
TATTAGTCAACTGTATCAGCAAAAACTAGACTACCAAATTGATTTGTTTGCTCAATTACTTGAACCGGTTTTAATGTTAG
TGATTGGCATTATTGTGGGGACGATTTTGATTGGGATTTATTTGCCTATTTTTGATATGGGAGCATTGGTGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)

Type II secretion system (T2SS), protein F (T2SSF)

(267-389)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Glaesserella parasuis strain SC1401

51.134

100

0.511
  pilC Haemophilus influenzae Rd KW20

39.75

100

0.401
  pilC Haemophilus influenzae 86-028NP

39.25

100

0.395

Multiple sequence alignment