Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   V471_RS07065 Genome accession   NZ_CP015283
Coordinates   1514140..1515555 (+) Length   471 a.a.
NCBI ID   WP_004182392.1    Uniprot ID   A0AB33ZDN7
Organism   Streptococcus salivarius strain ATCC 25975     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1509140..1520555
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V471_RS07040 (V471_06940) - 1509591..1510163 (-) 573 WP_084871334.1 ECF transporter S component -
  V471_RS07045 (V471_06945) coaC 1510192..1510737 (-) 546 WP_084871335.1 phosphopantothenoylcysteine decarboxylase -
  V471_RS07050 (V471_06950) - 1510730..1511413 (-) 684 WP_084871336.1 phosphopantothenate--cysteine ligase -
  V471_RS07055 (V471_06955) - 1511607..1513277 (+) 1671 WP_084871337.1 formate--tetrahydrofolate ligase -
  V471_RS07060 (V471_06960) ciaR 1513476..1514150 (+) 675 WP_049546057.1 response regulator transcription factor Regulator
  V471_RS07065 (V471_06965) ciaH 1514140..1515555 (+) 1416 WP_004182392.1 sensor histidine kinase Regulator
  V471_RS07070 (V471_06970) rpsT 1515633..1515869 (-) 237 WP_004182129.1 30S ribosomal protein S20 -
  V471_RS07075 (V471_06975) coaA 1515939..1516859 (-) 921 WP_004182393.1 type I pantothenate kinase -
  V471_RS07080 (V471_06980) - 1516972..1517562 (+) 591 WP_004182394.1 class I SAM-dependent methyltransferase -
  V471_RS07085 (V471_06985) - 1517559..1518836 (+) 1278 WP_004182395.1 pyrimidine-nucleoside phosphorylase -
  V471_RS07090 (V471_06990) deoC 1518870..1519532 (+) 663 WP_004182396.1 deoxyribose-phosphate aldolase -
  V471_RS07095 (V471_06995) - 1519519..1519917 (+) 399 WP_049527913.1 cytidine deaminase -

Sequence

Protein


Download         Length: 471 a.a.        Molecular weight: 53504.28 Da        Isoelectric Point: 8.7661

>NTDB_id=178315 V471_RS07065 WP_004182392.1 1514140..1515555(+) (ciaH) [Streptococcus salivarius strain ATCC 25975]
MLTKFFNYLFRRIKSDGFKSFIHFFATFSGIFLIMTVMILQILSYGVYSNVDSSLKMAATKTNSYLEMEMLKRELFLTSE
VDQNNTTTIYQAYDTKESTAETPDSSGSKKEPKKKSKIEDTPHDLSVAANTSVLVLDKNGKVLNVVDKFSSLSNLPIDKN
NIDVISKGSAQNYFDQTEKYRLITEKVDNSLYPDAKYLVIAINTTQLEEATERYVKLIVIMMSFFWLLSVAASMYLAKWS
RRPIQESLEKQKAFVENASHELRTPLAVIQNRLEVLFRKPESTILDNSENIASSLDEVRNMRLLTTNLLNLARRDDGIKP
EIETLEPAFFDTVFTNYAMIAEENEKGFTAQNQVGRPIQTDKTLLKQLMTILFDNAIKYTEDDGHVTFTVRTNDRHLYIS
VADNGPGISDSDKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIVLALKGTIVVKDNQPKGTIFEVKITGV

Nucleotide


Download         Length: 1416 bp        

>NTDB_id=178315 V471_RS07065 WP_004182392.1 1514140..1515555(+) (ciaH) [Streptococcus salivarius strain ATCC 25975]
ATGCTGACTAAATTTTTCAATTATCTCTTTAGGAGAATCAAGTCAGACGGATTTAAGTCGTTCATTCATTTCTTTGCCAC
TTTTTCTGGTATTTTCCTTATCATGACTGTCATGATTTTGCAGATTCTGAGTTACGGCGTTTATTCCAATGTGGACTCTA
GTCTGAAAATGGCAGCCACTAAAACCAATTCTTATTTAGAAATGGAAATGCTAAAACGGGAACTTTTTCTGACTTCTGAG
GTAGATCAAAATAATACGACAACCATTTACCAAGCCTATGATACTAAAGAGTCGACAGCTGAAACACCTGACTCGAGTGG
CTCTAAAAAAGAACCTAAGAAGAAATCAAAAATTGAAGATACCCCTCACGATTTATCTGTTGCGGCAAATACTAGTGTCT
TGGTACTTGATAAGAATGGAAAAGTCCTTAATGTCGTTGATAAATTTTCAAGCTTATCCAATTTACCAATAGACAAAAAT
AACATTGATGTTATCAGCAAGGGAAGTGCTCAGAATTATTTCGATCAAACGGAAAAGTACCGTCTGATTACTGAAAAAGT
AGATAATAGCCTCTATCCTGATGCTAAGTACCTTGTTATTGCGATTAATACAACTCAATTGGAAGAAGCCACTGAACGTT
ATGTTAAGCTAATTGTCATCATGATGAGTTTCTTCTGGCTTTTATCTGTTGCGGCTAGTATGTATTTGGCTAAGTGGTCA
AGACGTCCTATCCAGGAAAGCTTGGAGAAGCAGAAGGCTTTTGTTGAGAATGCTAGCCATGAGTTACGGACACCGCTTGC
TGTGATTCAAAACAGATTAGAAGTTCTTTTCCGCAAGCCTGAGAGCACCATTCTAGATAATTCAGAGAATATTGCTTCAA
GTCTTGATGAAGTACGCAACATGCGTCTTTTGACGACTAATCTTTTGAACTTGGCTCGTCGTGACGATGGTATTAAACCA
GAAATCGAAACCTTAGAACCTGCTTTCTTTGATACAGTATTTACCAACTATGCCATGATTGCAGAAGAAAATGAGAAAGG
TTTCACGGCTCAAAATCAAGTTGGTCGTCCAATCCAGACTGATAAAACGTTATTGAAACAGTTAATGACCATCTTATTTG
ATAATGCTATTAAATATACGGAAGATGATGGACATGTTACCTTTACTGTTCGCACTAATGACCGCCATCTTTATATTTCT
GTAGCTGATAATGGTCCTGGAATATCAGATAGTGATAAGAAAAAAATCTTTGATCGCTTTTATCGCGTAGATAAGGCTAG
AACCAGACAAAAAGGTGGGTTTGGACTTGGCTTATCTCTAGCGCAACAAATTGTTTTAGCCCTAAAAGGAACAATTGTTG
TTAAAGATAATCAACCAAAGGGAACGATTTTTGAAGTTAAGATCACCGGAGTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(361-468)

His Kinase A (phospho-acceptor) domain (HisKA)

(252-317)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.739

97.665

0.554
  ciaH Streptococcus pneumoniae Rx1

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae D39

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae R6

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae TIGR4

50.216

98.514

0.495

Multiple sequence alignment