Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   V471_RS01965 Genome accession   NZ_CP015283
Coordinates   391464..392420 (-) Length   318 a.a.
NCBI ID   WP_037601477.1    Uniprot ID   A0A074IXP5
Organism   Streptococcus salivarius strain ATCC 25975     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 386464..397420
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V471_RS01935 (V471_01940) proC 387006..387776 (+) 771 WP_084871053.1 pyrroline-5-carboxylate reductase -
  V471_RS01940 (V471_01945) - 387803..388465 (-) 663 WP_084871054.1 CPBP family intramembrane glutamic endopeptidase -
  V471_RS01945 (V471_01950) - 388578..389024 (-) 447 WP_084871055.1 CAAX protease -
  V471_RS01950 (V471_01955) - 389098..389754 (-) 657 WP_084871056.1 CPBP family intramembrane glutamic endopeptidase -
  V471_RS01955 (V471_01960) - 389766..389963 (-) 198 WP_002885716.1 helix-turn-helix transcriptional regulator -
  V471_RS01960 (V471_01965) - 390214..391407 (-) 1194 WP_003095894.1 acetate kinase -
  V471_RS01965 (V471_01970) comYH 391464..392420 (-) 957 WP_037601477.1 class I SAM-dependent methyltransferase Machinery gene
  V471_RS01970 (V471_01975) comGG 392465..392782 (-) 318 WP_037601475.1 competence type IV pilus minor pilin ComGG -
  V471_RS01975 (V471_01980) comYF 392760..393197 (-) 438 WP_037601472.1 competence type IV pilus minor pilin ComGF Machinery gene
  V471_RS01980 (V471_01985) comGE 393184..393414 (-) 231 WP_084871057.1 competence type IV pilus minor pilin ComGE -
  V471_RS01985 (V471_01990) comYD 393446..393874 (-) 429 WP_014632541.1 competence type IV pilus minor pilin ComGD Machinery gene
  V471_RS01990 (V471_01995) comYC 393834..394148 (-) 315 WP_037611125.1 competence type IV pilus major pilin ComGC Machinery gene
  V471_RS01995 (V471_02000) comYB 394157..395257 (-) 1101 WP_138261574.1 competence type IV pilus assembly protein ComGB Machinery gene
  V471_RS02000 (V471_02005) comGA/cglA/cilD 395139..396080 (-) 942 WP_002887018.1 competence type IV pilus ATPase ComGA Machinery gene

Sequence

Protein


Download         Length: 318 a.a.        Molecular weight: 35775.66 Da        Isoelectric Point: 4.3440

>NTDB_id=178272 V471_RS01965 WP_037601477.1 391464..392420(-) (comYH) [Streptococcus salivarius strain ATCC 25975]
MNFEAIETAFELLLENVQTIENDLGTHAYDALIEQNSYYLGAEVANEVIIKNNEKLRALDLSKEEWRRAFQFLFIKLGQL
EALQANHQFTPDAIGFIILYLLEGLTKDDQLDILEIGSGTGNLAETLLNNSQKTLNYMGMEVDDLLIDLSASIADVVNSS
AVYIQEDAVRPHILKESDVIISDLPVGYYPNDEIASRFKVAATGEHTYAHHLLMEQSLKYLKKDGIAILLAPTNLLTSPQ
SDLLKKWLSGYADIIAVITLPEAAFGNKHNMKSIFVLKKQTENAPETFVYPLSDLQNPEILKDFTDNFQKWKSDNSIF

Nucleotide


Download         Length: 957 bp        

>NTDB_id=178272 V471_RS01965 WP_037601477.1 391464..392420(-) (comYH) [Streptococcus salivarius strain ATCC 25975]
ATGAATTTTGAAGCAATTGAGACAGCTTTTGAGCTGTTGTTAGAAAATGTCCAAACCATTGAAAATGATCTTGGAACCCA
TGCTTACGATGCACTTATTGAGCAAAATTCCTATTATTTGGGGGCTGAGGTAGCTAATGAAGTCATCATCAAAAACAACG
AGAAATTACGTGCTCTTGATCTAAGTAAAGAGGAGTGGCGTCGTGCTTTTCAGTTCTTGTTTATCAAACTAGGGCAATTG
GAAGCTTTACAAGCCAATCACCAATTTACACCAGATGCTATTGGATTTATCATTCTTTACCTACTCGAAGGTTTGACCAA
GGACGACCAATTAGATATTTTAGAGATTGGTTCAGGGACAGGAAACTTAGCTGAAACCCTTCTAAATAATAGTCAGAAAA
CCCTTAATTATATGGGAATGGAAGTTGACGATCTCCTTATCGATTTGTCAGCTAGTATTGCTGATGTGGTGAATTCAAGT
GCAGTTTACATCCAAGAAGATGCTGTTCGACCACACATTCTCAAAGAGAGTGATGTTATTATCAGTGACCTACCTGTTGG
ATATTACCCAAATGATGAGATTGCGAGTCGTTTCAAGGTTGCAGCAACTGGTGAACACACCTATGCCCATCACCTTCTCA
TGGAGCAATCACTCAAGTACCTGAAGAAAGATGGTATTGCTATTCTTTTGGCACCAACTAATCTTTTGACAAGCCCACAA
AGTGACTTGCTTAAGAAATGGCTATCAGGATATGCTGATATTATTGCCGTTATCACTCTTCCAGAAGCAGCTTTTGGCAA
TAAACATAACATGAAGTCTATCTTCGTGCTTAAAAAACAAACTGAAAATGCTCCAGAGACCTTCGTTTATCCACTTAGCG
ATTTGCAAAACCCAGAGATCCTCAAGGATTTCACAGATAATTTCCAAAAATGGAAATCAGATAATTCCATTTTCTAG

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-293)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A074IXP5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA159

70.159

99.057

0.695
  comYH Streptococcus mutans UA140

70.159

99.057

0.695

Multiple sequence alignment