Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   NX99_RS05435 Genome accession   NZ_CP015282
Coordinates   1246393..1247082 (-) Length   229 a.a.
NCBI ID   WP_084915036.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ATCC 27945     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1241393..1252082
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NX99_RS05415 (NX99_05330) dnaI 1242188..1243090 (-) 903 WP_002883792.1 primosomal protein DnaI -
  NX99_RS05420 (NX99_05335) - 1243094..1244269 (-) 1176 WP_014633897.1 DnaD domain protein -
  NX99_RS05425 (NX99_05340) nrdR 1244266..1244745 (-) 480 WP_002883820.1 transcriptional regulator NrdR -
  NX99_RS05430 (NX99_05345) covS 1244867..1246396 (-) 1530 WP_014633896.1 HAMP domain-containing sensor histidine kinase Regulator
  NX99_RS05435 (NX99_05350) covR 1246393..1247082 (-) 690 WP_084915036.1 response regulator transcription factor Regulator
  NX99_RS05440 (NX99_05355) - 1247238..1247774 (-) 537 WP_084915038.1 DUF177 domain-containing protein -
  NX99_RS05445 (NX99_05360) rsmG 1248073..1248786 (+) 714 WP_084915040.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  NX99_RS05450 (NX99_05365) - 1248855..1250219 (+) 1365 WP_014633891.1 TrkH family potassium uptake protein -
  NX99_RS05455 (NX99_05370) - 1250259..1250930 (+) 672 WP_002889958.1 potassium channel family protein -
  NX99_RS05460 (NX99_05375) - 1251019..1251849 (-) 831 WP_037599013.1 energy-coupling factor transporter transmembrane component T family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26457.50 Da        Isoelectric Point: 4.6958

>NTDB_id=178217 NX99_RS05435 WP_084915036.1 1246393..1247082(-) (covR) [Streptococcus salivarius strain ATCC 27945]
MSKRILIVEDEKNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARIRATFRRQDIEAAKNAPAKASTYRALKLDVQNRTVVRGDEAIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDAIETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=178217 NX99_RS05435 WP_084915036.1 1246393..1247082(-) (covR) [Streptococcus salivarius strain ATCC 27945]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAAAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCAGACAACGGACGCGAAGGACTTGAAATGGCACTCGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTTGAAGTAACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCTCGCGATTCAATCATGGACATTGTTGCTGGTTTGGACCGCGGTGCTGATGACTATATTGTAAAACCATTTGCGATTGA
AGAATTGTTGGCACGTATCCGTGCAACCTTCCGTCGCCAAGATATCGAAGCTGCTAAGAATGCACCAGCCAAAGCATCAA
CTTATCGTGCTTTGAAATTGGATGTTCAAAACCGTACAGTTGTTCGTGGTGATGAAGCAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTGAGCAATATGAACCAAGTGATGACCCGTGAGGAACTCTTGCTTCAAGTTTGGAAATA
TGATGACGCCATCGAAACAAACGTGGTAGATGTTTATATTCGTTACTTGCGTGGAAAAATCGACGTTCCAGGTAAGGAAT
CATATATTCAAACAGTACGAGGAATGGGTTACGTTATCCGTGAAAAATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

99.563

100

0.996
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.982

99.563

0.677
  vicR Streptococcus mutans UA159

45.259

100

0.459
  micA Streptococcus pneumoniae Cp1015

43.913

100

0.441

Multiple sequence alignment