Detailed information NTG0178196

Bioinformatically predicted

Overview

• Name: ciaH
• Type: Regulator
• Locus tag: NX99_RS01155
• Genome accession: NZ_CP015282
• Coordinates: 347317..348732 (+)
• Length: 471 a.a.
• NCBI ID: WP_073687949.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain ATCC 27945
• Function: Required for optimal comC expression (predicted from homology) Competence regulation

Genomic Context

Location: 342317..353732

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NX99_RS01130 (NX99_01120)	-	342765..343337 (-)	573	WP_084914458.1	ECF transporter S component	-
NX99_RS01135 (NX99_01125)	coaC	343366..343911 (-)	546	WP_037600829.1	phosphopantothenoylcysteine decarboxylase	-
NX99_RS01140 (NX99_01130)	-	343904..344587 (-)	684	WP_037600832.1	phosphopantothenate--cysteine ligase	-
NX99_RS01145 (NX99_01135)	-	344783..346453 (+)	1671	WP_037600835.1	formate--tetrahydrofolate ligase	-
NX99_RS01150 (NX99_01140)	ciaR	346653..347327 (+)	675	WP_002891134.1	response regulator transcription factor	Regulator
NX99_RS01155 (NX99_01145)	ciaH	347317..348732 (+)	1416	WP_073687949.1	sensor histidine kinase	Regulator
NX99_RS01160 (NX99_01150)	rpsT	348810..349046 (-)	237	WP_004182129.1	30S ribosomal protein S20	-
NX99_RS01165 (NX99_01155)	coaA	349116..350036 (-)	921	WP_064525024.1	type I pantothenate kinase	-
NX99_RS01170 (NX99_01160)	-	350149..350739 (+)	591	WP_084914459.1	class I SAM-dependent methyltransferase	-
NX99_RS01175 (NX99_01165)	-	350736..352013 (+)	1278	WP_084914461.1	pyrimidine-nucleoside phosphorylase	-
NX99_RS01180 (NX99_01170)	deoC	352048..352710 (+)	663	WP_084914463.1	deoxyribose-phosphate aldolase	-
NX99_RS01185 (NX99_01175)	-	352697..353095 (+)	399	WP_084914464.1	cytidine deaminase	-

Sequence

Protein

• Length: 471 a.a.
• Molecular weight: 53476.25 Da
• Isoelectric Point: 7.9820

>NTDB_id=178196 NX99_RS01155 WP_073687949.1 347317..348732(+) (ciaH) [Streptococcus salivarius strain ATCC 27945]
MLTKFFNYLFRRIKSDGFKSFIHFFATFSGIFLIMTVMILQILSYGVYSNVDSSLKMAATKTNSYLEMEMLKRELFLTSE
VDQNNTTTIYQAYDTKESTAETPDSSGSKNEPKKKSKIEDAPHDLSVAANTSVLVLDKNGKVLNVVDKFSSLSNLPIDKN
NIDVISKGSAQNYFDQTEKYRLITEKVDNSLYPDAKYLVIAINTTQLEEATERYVKLIVIMMSFFWLLSVAASMYLAKWS
RRPIQESLEKQKAFVENASHELRTPLAVIQNRLEVLFRKPESTILDNSENIASSLDEVRNMRLLTTNLLNLARRDDGIKP
EIETLEPAFFDTVFTNYAMIAEENEKGFTAQNQVGRPIQTDKTLLKQLMTILFDNAIKYTEDDGHVTFTVRTNDRHLYIC
VADNGPGISDSDKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIVLALKGTIVVKDNQPKGTIFEVKITGV

Nucleotide

• Length: 1416 bp

>NTDB_id=178196 NX99_RS01155 WP_073687949.1 347317..348732(+) (ciaH) [Streptococcus salivarius strain ATCC 27945]
ATGCTGACTAAATTTTTCAATTATCTCTTTAGGAGAATCAAGTCAGACGGATTTAAGTCGTTCATTCATTTCTTTGCCAC
TTTTTCTGGTATTTTCCTTATCATGACTGTCATGATTTTGCAGATTCTGAGTTACGGCGTTTATTCCAATGTGGACTCTA
GTCTGAAAATGGCAGCCACTAAAACCAATTCTTATTTAGAAATGGAAATGCTAAAACGGGAACTTTTTCTGACTTCTGAG
GTAGATCAAAATAATACGACAACCATTTACCAAGCCTATGATACTAAAGAGTCGACAGCTGAAACACCCGACTCGAGTGG
CTCTAAAAATGAACCTAAGAAGAAATCAAAAATTGAAGATGCCCCTCACGATTTATCTGTTGCGGCAAACACCAGTGTCT
TAGTGCTTGATAAGAATGGAAAAGTCCTCAATGTCGTTGATAAATTTTCAAGCTTATCCAATTTACCAATAGATAAAAAT
AACATTGATGTTATCAGCAAGGGAAGTGCTCAGAATTATTTCGATCAAACGGAAAAGTATCGTCTGATCACTGAGAAAGT
AGACAATAGTCTCTATCCTGATGCTAAGTACCTTGTTATTGCGATTAATACAACTCAATTGGAAGAAGCCACTGAACGTT
ATGTCAAGCTAATTGTCATCATGATGAGTTTCTTCTGGCTCTTGTCAGTTGCAGCTAGTATGTATTTGGCCAAGTGGTCA
AGACGTCCTATCCAGGAAAGCTTGGAGAAGCAGAAAGCATTTGTTGAAAATGCTAGTCATGAGTTACGGACACCGCTTGC
TGTGATTCAAAACAGGTTAGAAGTTCTTTTCCGTAAGCCTGAGAGTACTATTTTAGATAATTCAGAGAATATTGCTTCAA
GTCTTGATGAAGTACGCAACATGCGTCTTTTGACGACTAATCTCTTAAACTTGGCTCGTCGTGACGATGGTATTAAACCA
GAAATTGAAACATTAGAACCTGCTTTCTTTGATACAGTATTTACCAACTATGCCATGATTGCAGAAGAAAATGAGAAAGG
TTTCACGGCTCAAAATCAAGTTGGTCGTCCAATCCAGACTGATAAAACGTTATTGAAGCAGCTAATGACCATCTTATTTG
ATAATGCTATTAAATATACGGAAGATGACGGACATGTTACCTTTACTGTTCGCACTAATGACCGCCATCTTTATATTTGT
GTAGCTGATAATGGTCCTGGAATATCAGATAGTGATAAGAAAAAAATCTTTGATCGCTTTTATCGCGTAGATAAGGCTAG
AACCAGACAAAAAGGTGGGTTTGGACTTGGCTTATCCCTAGCGCAACAAATTGTTTTAGCCCTAAAAGGAACAATTGTTG
TTAAAGATAATCAACCAAAGGGAACGATTTTTGAAGTTAAGATTACTGGAGTTTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (361-468)

• His Kinase A (phospho-acceptor) domain (HisKA) (252-317)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaH	Streptococcus mutans UA159	56.957	97.665	0.556
ciaH	Streptococcus pneumoniae Rx1	50.216	98.514	0.495
ciaH	Streptococcus pneumoniae D39	50.216	98.514	0.495
ciaH	Streptococcus pneumoniae R6	50.216	98.514	0.495
ciaH	Streptococcus pneumoniae TIGR4	50.216	98.514	0.495