Detailed information
Bioinformatically predicted
Overview
| Name | comEC/celB | Type | Machinery gene |
| Locus tag | A4H00_RS00555 | Genome accession | NZ_CP015196 |
| Coordinates | 114448..116685 (-) | Length | 745 a.a. |
| NCBI ID | WP_067086023.1 | Uniprot ID | - |
| Organism | Streptococcus marmotae strain HTS5 | ||
| Function | ssDNA transport into the cell (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 89982..126919 | 114448..116685 | within | 0 |
Gene organization within MGE regions
Location: 89982..126919
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| A4H00_RS00395 | - | 89982..90431 (-) | 450 | WP_067085947.1 | type II toxin-antitoxin system HicB family antitoxin | - |
| A4H00_RS00400 | - | 90469..90648 (-) | 180 | WP_067085951.1 | type II toxin-antitoxin system HicA family toxin | - |
| A4H00_RS00405 | - | 90834..91247 (-) | 414 | WP_067085954.1 | hypothetical protein | - |
| A4H00_RS00410 | - | 91228..91650 (-) | 423 | WP_067085956.1 | hypothetical protein | - |
| A4H00_RS00415 | - | 91696..91974 (-) | 279 | WP_067085959.1 | hypothetical protein | - |
| A4H00_RS00420 | - | 91964..92302 (-) | 339 | WP_067085961.1 | replication protein | - |
| A4H00_RS00425 | - | 92335..92913 (-) | 579 | WP_157770960.1 | hypothetical protein | - |
| A4H00_RS00430 | - | 93163..94419 (-) | 1257 | WP_067085967.1 | ISL3 family transposase | - |
| A4H00_RS00435 | - | 94602..94853 (-) | 252 | WP_067085970.1 | hypothetical protein | - |
| A4H00_RS00440 | - | 94850..95101 (-) | 252 | WP_067085973.1 | hypothetical protein | - |
| A4H00_RS00445 | - | 95409..96833 (-) | 1425 | WP_237334203.1 | virulence-associated E family protein | - |
| A4H00_RS00450 | - | 96826..97341 (-) | 516 | WP_067085974.1 | hypothetical protein | - |
| A4H00_RS00455 | - | 97334..97615 (-) | 282 | WP_067085977.1 | hypothetical protein | - |
| A4H00_RS00460 | - | 97625..97843 (-) | 219 | WP_067085980.1 | hypothetical protein | - |
| A4H00_RS00470 | - | 98018..98257 (-) | 240 | WP_067085985.1 | hypothetical protein | - |
| A4H00_RS11740 | - | 98513..98677 (-) | 165 | WP_157770961.1 | hypothetical protein | - |
| A4H00_RS00475 | - | 98670..99134 (-) | 465 | WP_067085987.1 | hypothetical protein | - |
| A4H00_RS00480 | - | 99194..99394 (-) | 201 | WP_067085989.1 | helix-turn-helix transcriptional regulator | - |
| A4H00_RS00485 | - | 99551..100315 (+) | 765 | WP_067085991.1 | XRE family transcriptional regulator | - |
| A4H00_RS00490 | - | 100358..101179 (+) | 822 | WP_067085994.1 | EbhA | - |
| A4H00_RS00495 | - | 101222..101779 (+) | 558 | WP_067085997.1 | GTP pyrophosphokinase | - |
| A4H00_RS00500 | - | 101941..102609 (+) | 669 | WP_067086000.1 | Fic family protein | - |
| A4H00_RS00505 | - | 102782..103927 (+) | 1146 | WP_067091309.1 | tyrosine-type recombinase/integrase | - |
| A4H00_RS00510 | queA | 104025..105053 (+) | 1029 | WP_067086002.1 | tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA | - |
| A4H00_RS00515 | - | 105121..106239 (-) | 1119 | WP_067086005.1 | aminotransferase | - |
| A4H00_RS00520 | sodA | 106343..106948 (-) | 606 | WP_067086007.1 | superoxide dismutase SodA | - |
| A4H00_RS00525 | holA | 107024..108055 (-) | 1032 | WP_067086010.1 | DNA polymerase III subunit delta | - |
| A4H00_RS00535 | - | 109084..110565 (-) | 1482 | WP_067086015.1 | hypothetical protein | - |
| A4H00_RS00540 | - | 110549..111442 (-) | 894 | WP_067086017.1 | ABC transporter ATP-binding protein | - |
| A4H00_RS12055 | - | 111809..112015 (+) | 207 | WP_206281834.1 | hypothetical protein | - |
| A4H00_RS00550 | - | 112287..113810 (-) | 1524 | WP_067086021.1 | class I adenylate-forming enzyme family protein | - |
| A4H00_RS00555 | comEC/celB | 114448..116685 (-) | 2238 | WP_067086023.1 | DNA internalization-related competence protein ComEC/Rec2 | Machinery gene |
| A4H00_RS00560 | comEA | 116669..117307 (-) | 639 | WP_067086025.1 | helix-hairpin-helix domain-containing protein | Machinery gene |
| A4H00_RS00565 | - | 117377..118123 (-) | 747 | WP_067086028.1 | lysophospholipid acyltransferase family protein | - |
| A4H00_RS00570 | - | 118219..118968 (+) | 750 | WP_067091314.1 | tRNA1(Val) (adenine(37)-N6)-methyltransferase | - |
| A4H00_RS00575 | - | 118910..119269 (+) | 360 | WP_067086031.1 | GIY-YIG nuclease family protein | - |
| A4H00_RS00580 | - | 119436..119846 (-) | 411 | WP_067086033.1 | GNAT family N-acetyltransferase | - |
| A4H00_RS00585 | - | 119939..120604 (-) | 666 | WP_067086036.1 | ArsR/SmtB family transcription factor | - |
| A4H00_RS00590 | - | 120981..124115 (-) | 3135 | WP_067086039.1 | GAG-binding domain-containing protein | - |
| A4H00_RS00600 | - | 124517..124834 (-) | 318 | WP_067086044.1 | hypothetical protein | - |
| A4H00_RS00605 | - | 124976..126223 (-) | 1248 | WP_067086046.1 | ABC transporter permease | - |
| A4H00_RS00610 | - | 126224..126919 (-) | 696 | WP_067086048.1 | ABC transporter ATP-binding protein | - |
Sequence
Protein
Download Length: 745 a.a. Molecular weight: 85251.99 Da Isoelectric Point: 8.9034
>NTDB_id=177408 A4H00_RS00555 WP_067086023.1 114448..116685(-) (comEC/celB) [Streptococcus marmotae strain HTS5]
MSQLIKRLPIAPIHLAVLLLALYFVMYRLSFLSVLLFLGLLVLLWFRQGRKVWYQVLPILGCFVLLFGLQRVKMMMDEGT
APTEVSQLLVKPDTIQVNGDSLTFRARSSGRLYTVFYQLKSEKEQAYFKHLSSLVDLEVEATVSEPEAQRNFNGFDYRDY
LRTQGIYRTVKISHITKIQKRFSWNPLDWLSVLRRKALVYIKEQFPNPMRHYMTGLLFGELDKEFDQMSDLYSSLGIIHL
FALSGMQVGFFVDKFRYLFLRLGLRKEIVDWLQVPFSFVYAGLTGFSVSVNRSLLQKMLANLGITKLDNMACTLVLSFLL
MPYFLLTAGGILSFAYAFLLTVFDFEELPHYKQVLVESLAISVGILPLLLYYFYSFQPLSILLTFLFSFVFDVVFLPGLS
IVFLLAPLIQLTQVNLFFVWMEACIQWVADLGFKPLIFGKPIATLLVVLLAVLLLTYDVYQNRKWRFVLISLAALLFFVV
KHPLENEITIVDIGQGDSIFLRDIRGRTVLIDVGGKVSFTAKESWQEKSAQANAERTLIPYLYSRGVSRIDTLVLTHTDT
DHVGDLVEVAQAVDIGCIYVSEGSLTVPDFIETLRGLRVPVHVVRVGGRIPIFDRFLEVLYPPTVGDGGNNDSVILYGNV
LQTRFLFTGDLEDGELDLVKTYPQLPVDVLKAGHHGSKGSSYPEFLDHISPKIALISAGKNNRYKHPHQETIDRFEERKV
QLFRTDEQGAIRFRGWKKWRIETVR
MSQLIKRLPIAPIHLAVLLLALYFVMYRLSFLSVLLFLGLLVLLWFRQGRKVWYQVLPILGCFVLLFGLQRVKMMMDEGT
APTEVSQLLVKPDTIQVNGDSLTFRARSSGRLYTVFYQLKSEKEQAYFKHLSSLVDLEVEATVSEPEAQRNFNGFDYRDY
LRTQGIYRTVKISHITKIQKRFSWNPLDWLSVLRRKALVYIKEQFPNPMRHYMTGLLFGELDKEFDQMSDLYSSLGIIHL
FALSGMQVGFFVDKFRYLFLRLGLRKEIVDWLQVPFSFVYAGLTGFSVSVNRSLLQKMLANLGITKLDNMACTLVLSFLL
MPYFLLTAGGILSFAYAFLLTVFDFEELPHYKQVLVESLAISVGILPLLLYYFYSFQPLSILLTFLFSFVFDVVFLPGLS
IVFLLAPLIQLTQVNLFFVWMEACIQWVADLGFKPLIFGKPIATLLVVLLAVLLLTYDVYQNRKWRFVLISLAALLFFVV
KHPLENEITIVDIGQGDSIFLRDIRGRTVLIDVGGKVSFTAKESWQEKSAQANAERTLIPYLYSRGVSRIDTLVLTHTDT
DHVGDLVEVAQAVDIGCIYVSEGSLTVPDFIETLRGLRVPVHVVRVGGRIPIFDRFLEVLYPPTVGDGGNNDSVILYGNV
LQTRFLFTGDLEDGELDLVKTYPQLPVDVLKAGHHGSKGSSYPEFLDHISPKIALISAGKNNRYKHPHQETIDRFEERKV
QLFRTDEQGAIRFRGWKKWRIETVR
Nucleotide
Download Length: 2238 bp
>NTDB_id=177408 A4H00_RS00555 WP_067086023.1 114448..116685(-) (comEC/celB) [Streptococcus marmotae strain HTS5]
ATGTCACAGTTGATTAAGCGCCTACCCATTGCTCCCATTCATTTAGCTGTTTTACTGTTGGCTCTTTATTTTGTGATGTA
CCGCCTATCCTTTTTATCTGTGCTCCTGTTTTTAGGCTTGTTAGTTTTACTCTGGTTTCGACAAGGGCGAAAAGTCTGGT
ATCAGGTGCTTCCGATTTTGGGCTGTTTTGTTCTCTTGTTCGGTCTACAAAGAGTGAAAATGATGATGGATGAAGGAACA
GCTCCGACAGAAGTTAGTCAACTATTGGTCAAACCAGACACCATTCAAGTCAACGGCGATAGCCTGACCTTTCGAGCAAG
GTCATCAGGGCGCTTGTATACTGTTTTTTATCAATTAAAAAGTGAGAAGGAGCAGGCTTATTTTAAGCATTTGTCAAGCT
TGGTGGACCTAGAAGTGGAGGCAACTGTATCTGAACCAGAAGCACAGCGAAATTTTAATGGATTTGATTATCGAGATTAT
TTAAGGACACAAGGGATTTATCGGACGGTCAAGATTAGCCACATCACAAAAATACAAAAGCGTTTTTCTTGGAATCCCTT
GGATTGGTTATCGGTACTTCGGCGCAAAGCATTGGTGTATATCAAGGAGCAGTTCCCAAATCCGATGCGACATTACATGA
CTGGGCTGTTGTTTGGAGAGTTGGACAAGGAGTTTGACCAAATGAGTGACCTGTATTCTAGTCTAGGCATTATTCATTTA
TTTGCTTTATCAGGGATGCAAGTGGGATTCTTTGTCGATAAATTTCGCTATCTTTTCTTGCGATTGGGTCTGCGAAAGGA
GATAGTCGATTGGCTGCAAGTCCCCTTTTCTTTTGTGTATGCTGGCTTGACAGGCTTTTCGGTCTCAGTCAATCGCTCCC
TTTTGCAGAAAATGTTAGCCAATCTAGGCATTACGAAATTGGACAATATGGCTTGTACGCTTGTCCTATCTTTCCTGCTT
ATGCCGTATTTTTTATTAACAGCTGGAGGTATCCTGAGTTTTGCTTATGCCTTTCTGCTGACAGTATTTGATTTTGAGGA
GTTGCCGCATTATAAGCAGGTACTAGTGGAGAGTTTAGCGATTTCAGTTGGGATTTTACCCTTGTTGCTCTATTATTTTT
ACAGCTTTCAACCCTTGTCTATCCTTCTAACCTTTCTCTTTTCCTTTGTTTTTGATGTTGTTTTCTTACCAGGACTCAGC
ATTGTGTTTTTGCTAGCACCCTTGATACAGCTTACGCAGGTTAATCTTTTCTTTGTTTGGATGGAGGCCTGCATTCAGTG
GGTAGCAGATCTGGGGTTCAAACCATTGATTTTCGGGAAACCGATAGCTACGCTATTAGTCGTCTTGCTGGCCGTTTTGC
TTCTTACGTATGATGTCTATCAGAACCGTAAATGGCGTTTCGTTCTCATCAGCTTAGCAGCTCTGCTATTTTTTGTCGTC
AAACATCCTTTGGAAAATGAGATCACAATAGTGGATATTGGACAAGGCGATAGCATCTTTTTGCGGGATATTCGTGGTCG
AACAGTTTTGATTGATGTTGGAGGAAAGGTGAGTTTTACTGCTAAAGAAAGTTGGCAGGAGAAGAGTGCACAAGCAAATG
CAGAGCGCACCTTGATTCCCTACCTTTATAGCCGTGGCGTGAGTCGGATTGACACACTTGTGTTAACGCATACTGATACA
GACCACGTGGGAGATCTGGTAGAAGTTGCACAAGCTGTAGACATTGGGTGCATTTACGTGTCTGAAGGAAGCTTGACGGT
TCCTGATTTTATAGAGACCCTGAGAGGGCTACGGGTTCCTGTTCATGTTGTACGAGTAGGAGGTAGGATTCCGATTTTTG
ACCGTTTTTTAGAAGTGCTTTATCCCCCTACAGTAGGAGATGGGGGAAATAATGATTCAGTGATTTTGTATGGAAATGTA
TTGCAGACGCGTTTTCTTTTTACAGGGGATTTAGAAGATGGGGAGTTGGACCTGGTTAAAACCTATCCGCAGTTACCAGT
TGATGTATTGAAGGCAGGACACCATGGCTCCAAAGGCTCATCCTATCCCGAATTTCTGGATCACATTTCACCAAAGATAG
CTTTGATTTCAGCTGGTAAAAATAATCGTTACAAACATCCTCATCAGGAGACAATAGATCGATTTGAGGAAAGGAAGGTA
CAGCTATTTCGGACCGATGAGCAAGGCGCTATTCGTTTTAGGGGCTGGAAAAAATGGCGGATTGAAACGGTGAGGTAA
ATGTCACAGTTGATTAAGCGCCTACCCATTGCTCCCATTCATTTAGCTGTTTTACTGTTGGCTCTTTATTTTGTGATGTA
CCGCCTATCCTTTTTATCTGTGCTCCTGTTTTTAGGCTTGTTAGTTTTACTCTGGTTTCGACAAGGGCGAAAAGTCTGGT
ATCAGGTGCTTCCGATTTTGGGCTGTTTTGTTCTCTTGTTCGGTCTACAAAGAGTGAAAATGATGATGGATGAAGGAACA
GCTCCGACAGAAGTTAGTCAACTATTGGTCAAACCAGACACCATTCAAGTCAACGGCGATAGCCTGACCTTTCGAGCAAG
GTCATCAGGGCGCTTGTATACTGTTTTTTATCAATTAAAAAGTGAGAAGGAGCAGGCTTATTTTAAGCATTTGTCAAGCT
TGGTGGACCTAGAAGTGGAGGCAACTGTATCTGAACCAGAAGCACAGCGAAATTTTAATGGATTTGATTATCGAGATTAT
TTAAGGACACAAGGGATTTATCGGACGGTCAAGATTAGCCACATCACAAAAATACAAAAGCGTTTTTCTTGGAATCCCTT
GGATTGGTTATCGGTACTTCGGCGCAAAGCATTGGTGTATATCAAGGAGCAGTTCCCAAATCCGATGCGACATTACATGA
CTGGGCTGTTGTTTGGAGAGTTGGACAAGGAGTTTGACCAAATGAGTGACCTGTATTCTAGTCTAGGCATTATTCATTTA
TTTGCTTTATCAGGGATGCAAGTGGGATTCTTTGTCGATAAATTTCGCTATCTTTTCTTGCGATTGGGTCTGCGAAAGGA
GATAGTCGATTGGCTGCAAGTCCCCTTTTCTTTTGTGTATGCTGGCTTGACAGGCTTTTCGGTCTCAGTCAATCGCTCCC
TTTTGCAGAAAATGTTAGCCAATCTAGGCATTACGAAATTGGACAATATGGCTTGTACGCTTGTCCTATCTTTCCTGCTT
ATGCCGTATTTTTTATTAACAGCTGGAGGTATCCTGAGTTTTGCTTATGCCTTTCTGCTGACAGTATTTGATTTTGAGGA
GTTGCCGCATTATAAGCAGGTACTAGTGGAGAGTTTAGCGATTTCAGTTGGGATTTTACCCTTGTTGCTCTATTATTTTT
ACAGCTTTCAACCCTTGTCTATCCTTCTAACCTTTCTCTTTTCCTTTGTTTTTGATGTTGTTTTCTTACCAGGACTCAGC
ATTGTGTTTTTGCTAGCACCCTTGATACAGCTTACGCAGGTTAATCTTTTCTTTGTTTGGATGGAGGCCTGCATTCAGTG
GGTAGCAGATCTGGGGTTCAAACCATTGATTTTCGGGAAACCGATAGCTACGCTATTAGTCGTCTTGCTGGCCGTTTTGC
TTCTTACGTATGATGTCTATCAGAACCGTAAATGGCGTTTCGTTCTCATCAGCTTAGCAGCTCTGCTATTTTTTGTCGTC
AAACATCCTTTGGAAAATGAGATCACAATAGTGGATATTGGACAAGGCGATAGCATCTTTTTGCGGGATATTCGTGGTCG
AACAGTTTTGATTGATGTTGGAGGAAAGGTGAGTTTTACTGCTAAAGAAAGTTGGCAGGAGAAGAGTGCACAAGCAAATG
CAGAGCGCACCTTGATTCCCTACCTTTATAGCCGTGGCGTGAGTCGGATTGACACACTTGTGTTAACGCATACTGATACA
GACCACGTGGGAGATCTGGTAGAAGTTGCACAAGCTGTAGACATTGGGTGCATTTACGTGTCTGAAGGAAGCTTGACGGT
TCCTGATTTTATAGAGACCCTGAGAGGGCTACGGGTTCCTGTTCATGTTGTACGAGTAGGAGGTAGGATTCCGATTTTTG
ACCGTTTTTTAGAAGTGCTTTATCCCCCTACAGTAGGAGATGGGGGAAATAATGATTCAGTGATTTTGTATGGAAATGTA
TTGCAGACGCGTTTTCTTTTTACAGGGGATTTAGAAGATGGGGAGTTGGACCTGGTTAAAACCTATCCGCAGTTACCAGT
TGATGTATTGAAGGCAGGACACCATGGCTCCAAAGGCTCATCCTATCCCGAATTTCTGGATCACATTTCACCAAAGATAG
CTTTGATTTCAGCTGGTAAAAATAATCGTTACAAACATCCTCATCAGGAGACAATAGATCGATTTGAGGAAAGGAAGGTA
CAGCTATTTCGGACCGATGAGCAAGGCGCTATTCGTTTTAGGGGCTGGAAAAAATGGCGGATTGAAACGGTGAGGTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comEC/celB | Streptococcus mitis SK321 |
53.949 |
100 |
0.541 |
| comEC/celB | Streptococcus mitis NCTC 12261 |
52.949 |
100 |
0.53 |
| comEC/celB | Streptococcus pneumoniae TIGR4 |
52.61 |
100 |
0.528 |
| comEC/celB | Streptococcus pneumoniae Rx1 |
51.807 |
100 |
0.519 |
| comEC/celB | Streptococcus pneumoniae D39 |
51.807 |
100 |
0.519 |
| comEC/celB | Streptococcus pneumoniae R6 |
51.807 |
100 |
0.519 |
| comEC | Lactococcus lactis subsp. cremoris KW2 |
46.267 |
100 |
0.466 |