Detailed information NTG0175964

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: PA8281_RS26815
• Genome accession: NZ_CP015002
• Coordinates: 5725984..5727321 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain PA8281
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5720984..5732321

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PA8281_RS26790 (PA8281_02761)	pgeF	5721127..5721855 (-)	729	WP_003119426.1	peptidoglycan editing factor PgeF	-
PA8281_RS26795 (PA8281_02762)	rluD	5721852..5722814 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
PA8281_RS26800 (PA8281_02763)	-	5722960..5723985 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
PA8281_RS26805 (PA8281_02764)	-	5724142..5724387 (+)	246	WP_003102591.1	PP0621 family protein	-
PA8281_RS26810 (PA8281_02765)	pilS	5724377..5725969 (+)	1593	WP_003119425.1	two-component system sensor histidine kinase PilS	Regulator
PA8281_RS26815 (PA8281_02766)	pilR	5725984..5727321 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
PA8281_RS26820 (PA8281_02767)	thiO	5727367..5728461 (-)	1095	WP_003119424.1	glycine oxidase ThiO	-
PA8281_RS26825 (PA8281_02768)	-	5728596..5729105 (+)	510	WP_003102595.1	GspH/FimT family pseudopilin	-
PA8281_RS26830 (PA8281_02769)	-	5729211..5729717 (+)	507	WP_003102598.1	GspH/FimT family pseudopilin	-
PA8281_RS26835 (PA8281_02770)	pilV	5729708..5730265 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
PA8281_RS26840 (PA8281_02771)	pilW	5730262..5731086 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
PA8281_RS26845 (PA8281_02772)	pilX	5731083..5731670 (+)	588	WP_015648054.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=175964 PA8281_RS26815 WP_003094694.1 5725984..5727321(+) (pilR) [Pseudomonas aeruginosa strain PA8281]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=175964 PA8281_RS26815 WP_003094694.1 5725984..5727321(+) (pilR) [Pseudomonas aeruginosa strain PA8281]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384