Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   BBX32_RS18110 Genome accession   NZ_CP018677
Coordinates   3736904..3737578 (-) Length   224 a.a.
NCBI ID   WP_000161505.1    Uniprot ID   A0A0D5YFC9
Organism   Acinetobacter baumannii strain LAC4     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 3731904..3742578
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BBX32_RS18085 (BBX32_18000) - 3732318..3733202 (+) 885 WP_005119709.1 LysR family transcriptional regulator -
  BBX32_RS18095 (BBX32_18005) - 3733505..3734692 (+) 1188 WP_002001094.1 ammonium transporter -
  BBX32_RS18100 (BBX32_18010) - 3734845..3735543 (+) 699 WP_000184469.1 phosphatase PAP2 family protein -
  BBX32_RS18105 (BBX32_18015) - 3735544..3736878 (-) 1335 WP_000559381.1 two-component system sensor histidine kinase PmrB -
  BBX32_RS18110 (BBX32_18020) ciaR 3736904..3737578 (-) 675 WP_000161505.1 response regulator transcription factor Regulator
  BBX32_RS18115 (BBX32_18025) - 3737593..3739242 (-) 1650 WP_031945247.1 phosphoethanolamine transferase -
  BBX32_RS18120 (BBX32_18030) - 3739423..3740718 (-) 1296 WP_000362906.1 DcaP family trimeric outer membrane transporter -
  BBX32_RS18125 (BBX32_18035) - 3741264..3742511 (-) 1248 WP_000489705.1 MFS transporter -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25548.47 Da        Isoelectric Point: 5.3246

>NTDB_id=175482 BBX32_RS18110 WP_000161505.1 3736904..3737578(-) (ciaR) [Acinetobacter baumannii strain LAC4]
MTKILMIEDDFMIAESTITLLQYHQFEVEWVNNGLDGLAQLAKTKFDLILLDLGLPMMDGMQVLKQIRQRAATPVLIISA
RDQLQNRVDGLNLGADDYLIKPYEFDELLARIHALLRRSGVEAQLASQDQLLESGDLVLNVEQHIATFKGQRIDLSNREW
AILIPLMTHPNKIFSKANLEDKLYDFDSDVTSNTIEVYVHHLRAKLGKDFIRTIRGLGYRLGQS

Nucleotide


Download         Length: 675 bp        

>NTDB_id=175482 BBX32_RS18110 WP_000161505.1 3736904..3737578(-) (ciaR) [Acinetobacter baumannii strain LAC4]
ATGACAAAAATCTTGATGATTGAAGATGATTTTATGATTGCAGAATCAACGATCACGTTGCTGCAATATCATCAATTTGA
GGTGGAATGGGTCAATAACGGTTTAGATGGTTTGGCTCAATTGGCGAAGACTAAATTTGATCTTATTCTTTTAGATTTAG
GGTTGCCTATGATGGATGGTATGCAAGTTTTGAAGCAGATCCGTCAAAGAGCAGCAACACCAGTATTAATTATTTCTGCT
CGAGATCAATTACAAAACCGTGTCGATGGTTTAAATTTGGGTGCAGATGATTATTTAATTAAACCTTATGAGTTTGATGA
GTTGCTTGCCCGTATTCATGCATTACTACGCCGTAGTGGAGTAGAAGCTCAACTTGCGAGTCAAGATCAACTATTAGAAA
GTGGCGATCTGGTTTTAAATGTTGAACAGCATATTGCGACTTTTAAAGGTCAACGCATTGATCTATCAAATCGTGAATGG
GCAATCTTAATTCCACTTATGACTCACCCAAATAAAATCTTTTCTAAAGCCAACTTAGAAGATAAGTTATATGATTTTGA
TAGTGATGTGACCAGTAATACTATTGAAGTATATGTTCACCATTTAAGAGCGAAGCTGGGTAAAGATTTTATTCGAACCA
TCCGAGGACTGGGCTACCGTTTGGGGCAATCATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(150-221)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 9OF3
  PDB 9OF4
  PDB 9OF5
  PDB 9OF6
  PDB 9OF7
  PDB 9OF8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.496

100

0.388
  ciaR Streptococcus pneumoniae D39

38.496

100

0.388
  ciaR Streptococcus pneumoniae R6

38.496

100

0.388
  ciaR Streptococcus pneumoniae TIGR4

38.496

100

0.388
  ciaR Streptococcus mutans UA159

37.445

100

0.379
  micA Streptococcus pneumoniae Cp1015

35.965

100

0.366

Multiple sequence alignment