Detailed information NTG0174914

Bioinformatically predicted

Overview

• Name: comA
• Type: Machinery gene
• Locus tag: PMA3_RS06150
• Genome accession: NZ_CP014870
• Coordinates: 1363654..1365876 (+)
• Length: 740 a.a.
• NCBI ID: WP_064676331.1
• Uniprot ID: A0A191YPG6
• Organism: Pseudomonas silesiensis strain A3
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1358654..1370876

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PMA3_RS06125 (PMA3_06120)	-	1359718..1360377 (+)	660	WP_064676326.1	transglutaminase-like domain-containing protein	-
PMA3_RS06130 (PMA3_06125)	-	1360421..1361044 (+)	624	WP_064676327.1	glutathione S-transferase family protein	-
PMA3_RS06135 (PMA3_06130)	-	1361178..1362110 (+)	933	WP_064676328.1	ABC transporter ATP-binding protein	-
PMA3_RS06140 (PMA3_06135)	-	1362107..1362886 (+)	780	WP_064676329.1	ABC transporter permease	-
PMA3_RS06145 (PMA3_06140)	-	1362999..1363517 (-)	519	WP_064676330.1	DUF2062 domain-containing protein	-
PMA3_RS06150 (PMA3_06145)	comA	1363654..1365876 (+)	2223	WP_064676331.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
PMA3_RS06155 (PMA3_06150)	exbB	1365974..1366612 (+)	639	WP_064676332.1	MotA/TolQ/ExbB proton channel family protein	Machinery gene
PMA3_RS06160 (PMA3_06155)	-	1366609..1367040 (+)	432	WP_064676333.1	ExbD/TolR family protein	-
PMA3_RS06165 (PMA3_06160)	lpxK	1367040..1368050 (+)	1011	WP_064676334.1	tetraacyldisaccharide 4'-kinase	-
PMA3_RS06170 (PMA3_06165)	-	1368076..1368261 (+)	186	WP_007945752.1	Trm112 family protein	-
PMA3_RS06175 (PMA3_06170)	kdsB	1368258..1369022 (+)	765	WP_064676335.1	3-deoxy-manno-octulosonate cytidylyltransferase	-
PMA3_RS06180 (PMA3_06175)	-	1369022..1369486 (+)	465	WP_064676336.1	low molecular weight protein-tyrosine-phosphatase	-
PMA3_RS06185 (PMA3_06180)	murB	1369483..1370502 (+)	1020	WP_064676337.1	UDP-N-acetylmuramate dehydrogenase	-

Sequence

Protein

• Length: 740 a.a.
• Molecular weight: 80978.20 Da
• Isoelectric Point: 10.4351

>NTDB_id=174914 PMA3_RS06150 WP_064676331.1 1363654..1365876(+) (comA) [Pseudomonas silesiensis strain A3]
MRTGMIALALGLLALRFLPVLPPVWFWLVLPVAALMMLPFRTYPLAFFLFGFSWACANAQWALDDRLPANLDGETRWVEG
RVVGLPQNGEAVVRFQLADAHSRRETVPPLIRLAWYGGPPVNSGEQWRLAVKLKRPAGLLNPHAFDYDAWLLAQRIGATG
TVKDGVRLQEARWAWRDGIRQRLQAVDAQGRTGALTALVLGDGAGLSREDWQVLQDTGTVHLLVISGQHIGLLAGLVYLL
IAGLPRYGLWPGRLPWLPWACGLAFAAALGYGLLAGFDVPVRRACVMIGLVLLWRLRFRHLGAWWPLLLALNAVLLLDPL
ASLQQGFWLSFAAVAVLIFIFGGRLGPWRWWQSWTRAQWLIAIGLGPILLILGLPISLSGPLVNLLAVPWISLVVLPPAL
LGTLLLPIPFVGEGLLWVAGGLIDLLFRGLALMAGRFPAWMPAAVPLWIGGLGALGALLLLMPRGVPLRPLGWPLLLLLV
FPPRQLLPEGTAEIWQLDVGQGLAILVRTRHHTLLYDAGPRFGDNDLGERVVLPTLRKLGVSGLDLMLISHAHADHAGGA
QAVAKGLPVRRVLSGEPLELPTELQAEACESGRQWTWDGVQFALWQWAAARESNPKSCVLQIEANGERLLLTGDIDTAAE
RALLDSPLAVTTDWLQSPHHGSRSSSSPALLAALQPAAALISRGQGNAFGHPHPTVLARYRQRGMAIHDSAEQGAIRLQL
GQFKPAWTMRQERRFWRPAP

Nucleotide

• Length: 2223 bp

>NTDB_id=174914 PMA3_RS06150 WP_064676331.1 1363654..1365876(+) (comA) [Pseudomonas silesiensis strain A3]
ATGCGCACAGGGATGATAGCGTTGGCGCTGGGTCTGCTGGCCCTGCGTTTTTTACCGGTACTACCGCCGGTCTGGTTTTG
GCTGGTGTTGCCGGTAGCGGCTTTGATGATGCTGCCGTTCAGGACGTATCCATTGGCATTTTTCCTGTTCGGCTTCAGTT
GGGCATGTGCGAATGCGCAGTGGGCCTTGGATGATCGCCTGCCCGCCAATCTGGATGGCGAAACCCGTTGGGTGGAAGGG
CGGGTGGTGGGATTGCCCCAGAATGGTGAGGCGGTCGTGCGTTTCCAATTGGCAGACGCCCATTCGCGACGCGAAACTGT
CCCGCCATTGATACGCCTGGCCTGGTACGGCGGGCCGCCGGTCAACAGCGGCGAACAGTGGCGACTGGCAGTGAAATTGA
AGCGTCCTGCGGGGCTGCTCAATCCACATGCCTTCGATTACGACGCCTGGCTGCTGGCGCAACGCATCGGCGCCACCGGG
ACGGTCAAGGATGGCGTGCGTCTCCAGGAAGCTCGATGGGCCTGGCGCGACGGCATCCGCCAACGCTTGCAGGCGGTGGA
TGCCCAAGGCCGAACGGGAGCGCTGACGGCGCTGGTGCTGGGGGATGGCGCCGGGCTCAGTCGCGAGGATTGGCAGGTGT
TGCAAGACACCGGCACCGTGCATTTGCTGGTAATTTCCGGGCAGCACATTGGCTTGCTCGCGGGGCTGGTGTACCTGCTG
ATCGCCGGCCTGCCTCGTTATGGCCTGTGGCCGGGGCGTCTGCCCTGGCTGCCATGGGCCTGCGGCCTGGCCTTCGCCGC
TGCGCTCGGTTATGGGTTGCTGGCCGGTTTCGACGTGCCCGTGCGGCGAGCCTGCGTGATGATCGGCCTGGTGCTGTTGT
GGCGGCTGCGCTTTCGCCATCTCGGTGCCTGGTGGCCGTTGTTGCTGGCGCTCAACGCCGTTCTGCTGCTGGACCCGCTG
GCGAGTCTGCAGCAGGGTTTCTGGTTGTCTTTCGCCGCGGTAGCCGTGTTGATCTTCATTTTCGGCGGCCGGCTGGGTCC
CTGGCGCTGGTGGCAATCCTGGACTCGCGCCCAGTGGCTGATCGCGATCGGCCTGGGCCCGATATTGCTGATACTGGGCT
TGCCGATCAGCCTCAGCGGGCCGCTGGTCAATCTGCTGGCCGTGCCCTGGATCAGTCTGGTGGTGCTGCCGCCAGCCTTG
CTGGGGACGCTGCTGTTGCCCATCCCTTTTGTGGGCGAGGGGTTGCTGTGGGTGGCGGGAGGCTTGATCGATCTGTTGTT
CAGGGGCCTTGCACTGATGGCCGGGCGTTTCCCCGCGTGGATGCCGGCGGCGGTACCGTTGTGGATAGGGGGCCTGGGGG
CACTGGGTGCGTTGCTGCTGTTAATGCCTCGCGGGGTGCCCCTGCGCCCGTTGGGTTGGCCGCTGCTGCTGTTGCTGGTA
TTTCCACCCCGCCAACTGTTGCCGGAGGGCACGGCCGAAATCTGGCAACTGGACGTCGGCCAGGGACTGGCCATCCTGGT
GCGCACCCGTCATCACACGCTGTTGTACGACGCCGGGCCACGTTTCGGCGATAACGACCTCGGCGAGCGCGTGGTACTGC
CGACGCTGCGCAAACTGGGGGTGAGCGGCCTCGACCTGATGCTGATCAGCCACGCCCATGCCGATCACGCCGGCGGGGCG
CAGGCCGTCGCCAAAGGGTTGCCGGTGAGGCGCGTGCTCAGTGGCGAACCCTTGGAGTTGCCCACCGAGCTGCAAGCCGA
GGCCTGCGAGAGCGGCCGGCAATGGACCTGGGACGGTGTGCAGTTCGCGCTCTGGCAATGGGCAGCAGCCCGGGAAAGCA
ACCCAAAATCCTGCGTGTTGCAGATCGAAGCCAACGGCGAGCGGTTGCTGCTGACCGGTGACATCGACACCGCGGCCGAG
CGGGCCCTGCTCGACAGCCCCCTGGCGGTGACAACCGATTGGTTGCAGTCGCCACACCATGGCAGTCGCAGTTCATCTTC
GCCGGCGCTGCTTGCCGCGTTGCAACCCGCGGCGGCGCTGATCTCCCGCGGCCAGGGCAATGCCTTCGGCCATCCCCATC
CCACGGTCTTGGCGCGTTACCGACAGCGTGGCATGGCGATACATGACAGCGCCGAACAGGGTGCCATCCGTCTGCAACTG
GGACAGTTCAAGCCAGCCTGGACAATGCGTCAGGAACGGCGTTTCTGGCGCCCTGCACCCTGA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (23-165)

• Metallo-beta-lactamase superfamily (Lactamase_B) (498-681)

• Competence protein (Competence) (198-464)

3D structure

• AlphaFold DB: A0A191YPG6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Pseudomonas stutzeri DSM 10701	63.202	96.216	0.608
comA	Ralstonia pseudosolanacearum GMI1000	34.293	100	0.386