Detailed information NTG0174505

Bioinformatically predicted

Overview

• Name: vicK
• Type: Regulator
• Locus tag: A2G56_RS09770
• Genome accession: NZ_CP014835
• Coordinates: 2134637..2135983 (+)
• Length: 448 a.a.
• NCBI ID: WP_062712138.1
• Uniprot ID: -
• Organism: Streptococcus halotolerans strain HTS9
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 2129637..2140983

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A2G56_RS09745	-	2130698..2131348 (-)	651	WP_062712123.1	amino acid ABC transporter permease	-
A2G56_RS09750	-	2131357..2132055 (-)	699	WP_062712127.1	amino acid ABC transporter permease	-
A2G56_RS09755	-	2132075..2132902 (-)	828	WP_062712129.1	transporter substrate-binding domain-containing protein	-
A2G56_RS09760	-	2132919..2133701 (-)	783	WP_062712131.1	amino acid ABC transporter ATP-binding protein	-
A2G56_RS09765	vicR	2133937..2134644 (+)	708	WP_062712133.1	response regulator YycF	Regulator
A2G56_RS09770	vicK	2134637..2135983 (+)	1347	WP_062712138.1	cell wall metabolism sensor histidine kinase VicK	Regulator
A2G56_RS09775	vicX	2135985..2136794 (+)	810	WP_062712141.1	MBL fold metallo-hydrolase	Regulator
A2G56_RS09780	rnc	2136930..2137631 (+)	702	WP_099091487.1	ribonuclease III	-

Sequence

Protein

• Length: 448 a.a.
• Molecular weight: 51087.12 Da
• Isoelectric Point: 4.6011

>NTDB_id=174505 A2G56_RS09770 WP_062712138.1 2134637..2135983(+) (vicK) [Streptococcus halotolerans strain HTS9]
MTDQFIFTFRDLIIAGLMSILVLIYVFLIINDSLNSRRVQQLTEQVQSLISGEYVVNQVTRGSAEVRTLAEHLNDLSEVF
RLTHENLGQEKNRLSSILSYMSDGVLATDRRGNIIMINDMARQQLNLSEEEDISVNIMTLLEETSYTYHDLITKTPEVTL
NRVDEFGEFTVLRINFALIKRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALKESV
APGFIRVSLDETNRMMRMISDLLSLSRIDNNNSHLEVELTNFTAFITYILNRFDQIKLQETQAGKSYDIIRNYPLVPVWI
EIDNDKMTQVIDNIINNAIKYSPDGGEITVSMRTTETQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGLGL
AIAKEIIKQHNGFIWAKSDYGKGSTLTIVLPYEKNILEVDEEWEVTED

Nucleotide

• Length: 1347 bp

>NTDB_id=174505 A2G56_RS09770 WP_062712138.1 2134637..2135983(+) (vicK) [Streptococcus halotolerans strain HTS9]
ATGACTGATCAATTTATTTTTACATTTAGAGATTTAATTATTGCAGGACTAATGTCTATCTTAGTCCTGATTTATGTTTT
TTTAATCATCAATGACTCGCTTAATAGCCGGCGAGTGCAGCAATTGACCGAGCAGGTTCAGTCATTGATTTCAGGTGAGT
ACGTTGTTAATCAAGTAACACGTGGTTCAGCAGAAGTTAGGACTTTGGCAGAACACCTCAATGATTTGTCGGAAGTGTTT
CGATTGACTCATGAGAATTTAGGGCAAGAAAAAAACCGGCTTTCTAGTATCTTGTCTTATATGAGTGATGGTGTTTTGGC
AACGGATCGGCGTGGTAATATCATCATGATTAATGACATGGCGAGACAGCAGTTAAACTTGTCAGAAGAAGAGGATATTT
CCGTCAATATTATGACCTTGTTGGAAGAGACTTCTTATACTTATCATGATTTGATCACGAAAACACCTGAGGTCACTCTC
AATCGAGTCGATGAGTTTGGTGAGTTTACTGTTTTAAGAATTAATTTTGCTTTGATTAAGCGAGAAAGTGGTTTTATTTC
AGGATTGGTTGCCGTTCTTCATGATACGACTGAACAGGAAAAAGAAGAACGCGAACGTCGCCTCTTTGTTTCGAATGTTA
GCCATGAACTACGAACTCCTTTAACATCAGTAAAATCCTACTTAGAAGCCCTTGATGAAGGTGCCCTAAAGGAATCGGTT
GCTCCTGGCTTTATACGTGTGTCTCTGGATGAGACTAACCGGATGATGCGAATGATTTCTGATTTGCTTTCCTTATCACG
AATTGATAATAATAACTCGCATTTAGAGGTTGAATTGACTAACTTTACAGCCTTTATAACTTACATCCTTAATCGTTTCG
ATCAGATCAAACTTCAGGAAACGCAAGCTGGCAAATCCTATGACATTATTCGAAATTATCCCTTGGTGCCTGTTTGGATT
GAGATTGATAATGACAAAATGACACAGGTTATTGATAATATTATCAATAATGCGATTAAGTATTCACCTGACGGTGGTGA
GATTACAGTTAGCATGCGAACAACTGAAACTCAGTTAATTATTTCGATTTCCGATCAAGGTTTGGGAATTCCAAAGAAAG
ATTTGCCACTTATTTTTGATCGATTTTATCGAGTCGACAAGGCTCGGAGCCGTGCACAAGGTGGCACTGGTCTTGGACTT
GCTATTGCCAAAGAGATTATTAAACAACATAATGGCTTTATTTGGGCCAAAAGTGACTACGGCAAGGGCTCAACCCTTAC
CATAGTATTACCGTATGAAAAGAATATTTTAGAAGTAGATGAAGAATGGGAGGTGACTGAAGACTAA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (206-270)

• PAS fold (PAS) (93-157)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (323-433)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicK	Streptococcus mutans UA159	72.019	91.741	0.661
micB	Streptococcus pneumoniae Cp1015	66.051	96.652	0.638