Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   A0O21_RS06515 Genome accession   NZ_CP014699
Coordinates   1415296..1417530 (-) Length   744 a.a.
NCBI ID   WP_067063189.1    Uniprot ID   A0A172Q8C8
Organism   Streptococcus pantholopis strain TA 26     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1410296..1422530
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A0O21_RS06490 (A0O21_06490) - 1410374..1410970 (+) 597 WP_067063168.1 TetR/AcrR family transcriptional regulator -
  A0O21_RS06495 (A0O21_06495) - 1411009..1412112 (-) 1104 WP_067063172.1 serine hydrolase -
  A0O21_RS06500 (A0O21_06500) sodA 1412339..1412950 (-) 612 WP_067063176.1 superoxide dismutase SodA -
  A0O21_RS06505 (A0O21_06505) holA 1413120..1414172 (-) 1053 WP_067063180.1 DNA polymerase III subunit delta -
  A0O21_RS06510 (A0O21_06510) - 1414368..1415078 (-) 711 WP_067063185.1 DUF805 domain-containing protein -
  A0O21_RS06515 (A0O21_06515) comEC/celB 1415296..1417530 (-) 2235 WP_067063189.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  A0O21_RS06520 (A0O21_06520) - 1417520..1418197 (-) 678 WP_067063193.1 helix-hairpin-helix domain-containing protein -
  A0O21_RS06525 (A0O21_06525) - 1418343..1419083 (-) 741 WP_067063197.1 lysophospholipid acyltransferase family protein -
  A0O21_RS06530 (A0O21_06530) - 1419828..1420841 (+) 1014 WP_067063201.1 GIY-YIG nuclease family protein -

Sequence

Protein


Download         Length: 744 a.a.        Molecular weight: 85617.71 Da        Isoelectric Point: 10.0084

>NTDB_id=173358 A0O21_RS06515 WP_067063189.1 1415296..1417530(-) (comEC/celB) [Streptococcus pantholopis strain TA 26]
MLINFYLVKPIHLAFLLLLLYFWLFSAEPLALFLLILALICLFKQYTWQKVLTAAVVLGFFAVYFCIWQKQQSRAYQAAP
KSVSYIEMIPDSIAINGDLLSFQGQSSKEEYQVFYRLRSKTEKDFFSHLDETVILQAEANTEEAESIRNFNGFDYRSYLK
NRGIYRLINLNKIQTVRRPFKKSIVTCFREWRRKAIVFIQSQFPAPMRHYMTGLLFGYLDKSFDEMTDLYTNLGLIHLFA
LSGMHVSFFIRLFRFCFLRLGVRRDYVDYLQIPFSFLYAVLTGFSVSVIRSLVQNAFSRLGVKKMDNLALTLIAFFLLMP
HFLLTRAGILSFAYAFILTLIDFSHLSSYKKKIMESLALAAGILPILLYFFSVFQPLSVLLTAFFSMTFEFLLLPMLVFI
FLISPIVKLTFVNVLFLFLETFITWISQLFRHPFVLGRPHLLVLILLLILLGLLYDFCRQKKIAIVLSLSIALLLFSSKF
PLGNELTVVDVGQGDSILLRDQRGKTVLIDVGGRPVFTSKESWQERTGKSNAERTLIPYLRSRGISKIDQLVLTHADTDH
VGDLQVLAKYFKIGEILVSYGSLTQTDFVQRLKATRTKVRTVKAGDSLSIMQSRLYVLYPYKKGDGGNNDSLVLYGRLLN
QTFLFTGDLENTGEKELMQIYKELPVDVLKAGHHGSKGSTSSEFLNFIKPKYALISAGFHNRYRHPHQETLDRLSAAAVE
VYRTDLQGAIRFRGWNSWQIETVK

Nucleotide


Download         Length: 2235 bp        

>NTDB_id=173358 A0O21_RS06515 WP_067063189.1 1415296..1417530(-) (comEC/celB) [Streptococcus pantholopis strain TA 26]
CTGTTGATTAATTTCTATTTGGTAAAGCCGATTCATTTAGCCTTTTTATTGCTTTTACTTTATTTTTGGCTGTTTTCTGC
AGAGCCTTTAGCTCTGTTTCTGCTGATCCTTGCTTTGATTTGCTTGTTTAAGCAGTACACTTGGCAAAAAGTCTTAACTG
CTGCAGTGGTATTAGGTTTTTTTGCTGTTTATTTTTGTATCTGGCAGAAGCAGCAGTCAAGAGCATATCAGGCAGCTCCC
AAGTCTGTCAGTTACATCGAAATGATCCCTGACAGTATAGCAATTAATGGTGATCTGCTTTCTTTTCAGGGGCAGTCTTC
TAAAGAAGAATACCAAGTTTTTTACCGGCTCAGGTCAAAAACAGAAAAAGATTTTTTTAGCCATCTTGATGAGACGGTTA
TCCTGCAGGCAGAAGCCAATACGGAAGAAGCGGAAAGCATACGCAATTTTAATGGCTTCGATTACCGCAGCTACCTAAAA
AATCGGGGAATTTACAGGCTGATTAATCTTAATAAAATTCAAACAGTCCGGCGGCCATTCAAAAAATCTATTGTCACCTG
TTTTCGAGAATGGCGGCGCAAAGCCATTGTCTTTATTCAAAGTCAGTTTCCTGCCCCAATGCGGCATTATATGACAGGAC
TTCTGTTTGGTTATTTGGATAAATCATTTGATGAGATGACCGATTTATACACCAACCTTGGCCTTATCCACCTGTTTGCC
TTATCAGGAATGCATGTCAGTTTTTTTATACGGCTTTTCCGATTTTGTTTTTTACGACTGGGTGTAAGGCGTGATTATGT
AGATTACCTGCAGATTCCTTTTTCATTTCTGTATGCTGTTTTGACAGGATTTTCTGTTTCTGTTATCCGCAGCCTAGTCC
AAAATGCTTTCTCCAGACTTGGAGTTAAAAAGATGGACAATTTAGCATTGACACTGATTGCTTTTTTTCTGCTAATGCCG
CATTTTCTCTTAACAAGAGCCGGGATACTGTCTTTTGCCTATGCTTTTATATTAACTTTGATAGATTTTTCTCATCTCAG
CAGCTATAAAAAGAAAATAATGGAAAGTTTAGCGCTTGCTGCAGGGATATTACCCATTTTGCTCTACTTTTTTTCGGTTT
TTCAGCCCTTGTCTGTTCTGCTTACAGCCTTCTTTTCCATGACTTTCGAGTTTCTTCTTTTGCCTATGTTGGTCTTCATT
TTTCTAATTTCACCTATTGTTAAACTGACCTTTGTTAATGTTCTCTTTCTTTTTCTGGAAACATTTATCACCTGGATTAG
TCAGCTTTTCCGTCACCCCTTTGTTTTGGGACGGCCTCATTTATTAGTCCTTATTTTACTGCTGATTTTGCTGGGCCTGC
TTTATGATTTTTGCCGTCAAAAGAAGATAGCTATAGTCCTGAGCCTATCGATTGCCCTCTTGCTTTTTAGCAGTAAATTT
CCTTTGGGAAATGAGCTGACAGTAGTCGATGTTGGGCAGGGCGACAGTATTCTTTTGAGAGATCAGAGAGGGAAAACAGT
CTTGATTGATGTCGGTGGTCGGCCGGTATTTACCAGTAAAGAAAGCTGGCAGGAAAGGACAGGAAAAAGTAATGCTGAAA
GAACTCTGATTCCGTATCTGCGCAGCCGCGGAATCAGTAAAATTGACCAGCTGGTCTTAACGCATGCCGATACTGACCAT
GTTGGAGACTTACAGGTTCTTGCCAAATATTTTAAAATTGGAGAAATCTTAGTCAGTTACGGCAGTTTGACACAGACCGA
TTTTGTCCAAAGATTAAAGGCGACGAGAACTAAGGTGCGTACCGTTAAAGCAGGAGACAGTCTTTCAATCATGCAGAGCC
GTTTATATGTTCTTTATCCTTATAAAAAAGGAGACGGCGGCAACAACGACTCTCTGGTGCTGTATGGGCGTTTGCTAAAT
CAGACCTTTCTATTTACAGGTGATTTAGAAAATACAGGTGAAAAGGAGTTGATGCAGATCTATAAGGAATTGCCTGTTGA
TGTCTTAAAAGCAGGGCATCATGGGAGCAAGGGGTCGACCAGTTCAGAGTTTTTAAACTTTATTAAACCTAAATATGCTT
TAATCTCTGCCGGCTTTCACAATCGCTACCGGCATCCCCATCAGGAGACATTGGATCGGCTGAGCGCTGCTGCTGTTGAG
GTTTATCGGACAGACCTGCAGGGAGCCATCCGTTTTCGGGGCTGGAACAGCTGGCAGATAGAGACCGTAAAATGA

Domains

Predicted by InterproScan.

Competence protein (Competence)

(214-455)

Metallo-beta-lactamase superfamily (Lactamase_B)

(490-698)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A172Q8C8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis NCTC 12261

50.611

99.059

0.501
  comEC/celB Streptococcus mitis SK321

50.542

99.194

0.501
  comEC/celB Streptococcus pneumoniae TIGR4

49.458

99.194

0.491
  comEC/celB Streptococcus pneumoniae Rx1

48.645

99.194

0.483
  comEC/celB Streptococcus pneumoniae D39

48.645

99.194

0.483
  comEC/celB Streptococcus pneumoniae R6

48.645

99.194

0.483
  comEC Lactococcus lactis subsp. cremoris KW2

45.527

100

0.458

Multiple sequence alignment