Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   A0O21_RS01145 Genome accession   NZ_CP014699
Coordinates   240248..240937 (+) Length   229 a.a.
NCBI ID   WP_067060230.1    Uniprot ID   A0A172Q5K4
Organism   Streptococcus pantholopis strain TA 26     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 235248..245937
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A0O21_RS01125 (A0O21_01135) rsmG 236347..237060 (-) 714 WP_067060222.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  A0O21_RS01130 (A0O21_01140) - 237347..237904 (+) 558 WP_067060224.1 LemA family protein -
  A0O21_RS01135 (A0O21_01145) htpX 238372..239265 (+) 894 WP_067060226.1 zinc metalloprotease HtpX -
  A0O21_RS01140 (A0O21_01150) - 239479..240012 (+) 534 WP_067060228.1 YceD family protein -
  A0O21_RS01145 (A0O21_01155) covR 240248..240937 (+) 690 WP_067060230.1 response regulator transcription factor Regulator
  A0O21_RS01150 (A0O21_01160) nrdR 241187..241681 (+) 495 WP_067060232.1 transcriptional regulator NrdR -
  A0O21_RS01155 (A0O21_01165) - 241668..242849 (+) 1182 WP_067060234.1 DnaD domain protein -
  A0O21_RS01160 (A0O21_01170) dnaI 242850..243761 (+) 912 WP_067060236.1 primosomal protein DnaI -
  A0O21_RS01165 (A0O21_01175) der 243947..245257 (+) 1311 WP_067060238.1 ribosome biogenesis GTPase Der -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26643.79 Da        Isoelectric Point: 5.0937

>NTDB_id=173337 A0O21_RS01145 WP_067060230.1 240248..240937(+) (covR) [Streptococcus pantholopis strain TA 26]
MIKKILIIEDEKNLARFVSLELQHEGYEVQIESNGRKGLDLALEKDFDLVLLDLMLPEMDGFEITRRLQAEKNTYIMMMT
ARDSVLDIVAGLDRGADDYIVKPFAIEELLARVRAIFRRQNMESNKKAHAAQGSYRDLTMNPQNRSVLRGDDEISLTKRE
YDLLNILMINMNRVMTREELLANVWKYEEAAETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYMIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=173337 A0O21_RS01145 WP_067060230.1 240248..240937(+) (covR) [Streptococcus pantholopis strain TA 26]
GTGATTAAGAAAATTTTGATTATTGAAGATGAAAAAAATTTGGCGCGATTTGTTTCCTTGGAACTGCAGCATGAAGGCTA
TGAAGTTCAGATTGAATCAAATGGGAGAAAAGGGCTGGATTTAGCTCTCGAAAAAGATTTTGATTTGGTTCTTTTGGATT
TGATGCTGCCGGAGATGGATGGATTTGAAATTACACGCAGACTTCAGGCTGAGAAAAATACCTATATCATGATGATGACA
GCCAGAGATTCTGTTTTGGACATTGTGGCGGGCTTGGACCGCGGTGCTGACGACTATATTGTTAAACCGTTTGCTATTGA
AGAATTGCTGGCACGGGTTCGTGCTATTTTCCGCCGGCAAAATATGGAATCCAATAAAAAGGCACATGCAGCGCAAGGTT
CTTATCGGGACTTGACAATGAATCCTCAGAACCGTTCTGTTCTTAGAGGGGATGATGAAATTTCACTGACCAAACGTGAA
TATGACCTGCTGAATATTTTGATGATAAATATGAATCGCGTTATGACACGGGAAGAGCTGCTGGCAAATGTGTGGAAGTA
TGAAGAAGCAGCCGAAACAAATGTTGTTGATGTTTATATTCGTTATTTGCGCGGGAAAATTGATGTTCCCGGCAAGGAGT
CATATATTCAGACCGTCCGCGGTATGGGCTATATGATTCGTGAAAAGTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A172Q5K4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

78.603

100

0.786
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.96

99.127

0.664
  vicR Streptococcus mutans UA159

41.81

100

0.424
  micA Streptococcus pneumoniae Cp1015

40.343

100

0.41

Multiple sequence alignment