Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   AXE83_RS08330 Genome accession   NZ_CP014264
Coordinates   1779710..1780372 (+) Length   220 a.a.
NCBI ID   WP_060956111.1    Uniprot ID   A0A0X8JZ76
Organism   Streptococcus sp. oral taxon 431 strain F0610 (5-114)     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1774710..1785372
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AXE83_RS08295 (AXE83_08295) - 1776150..1776377 (-) 228 WP_000660082.1 hypothetical protein -
  AXE83_RS08300 (AXE83_08300) - 1776469..1776849 (-) 381 WP_000259323.1 rhodanese-like domain-containing protein -
  AXE83_RS08305 (AXE83_08305) - 1776855..1777079 (-) 225 WP_000646475.1 YqgQ family protein -
  AXE83_RS08310 (AXE83_08310) - 1777148..1777609 (-) 462 WP_000814958.1 ECF transporter S component -
  AXE83_RS08315 (AXE83_08315) - 1777587..1778360 (-) 774 WP_060956109.1 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase -
  AXE83_RS08320 (AXE83_08320) truA 1778350..1779099 (-) 750 WP_045763152.1 tRNA pseudouridine(38-40) synthase TruA -
  AXE83_RS08325 (AXE83_08325) - 1779185..1779640 (-) 456 WP_060956110.1 GNAT family N-acetyltransferase -
  AXE83_RS08330 (AXE83_08330) cclA/cilC 1779710..1780372 (+) 663 WP_060956111.1 A24 family peptidase Machinery gene
  AXE83_RS08335 (AXE83_08335) trpA 1780341..1781123 (-) 783 WP_060956112.1 tryptophan synthase subunit alpha -
  AXE83_RS08340 (AXE83_08340) trpB 1781116..1782339 (-) 1224 WP_060956113.1 tryptophan synthase subunit beta -
  AXE83_RS08345 (AXE83_08345) - 1782317..1782916 (-) 600 WP_060956114.1 phosphoribosylanthranilate isomerase -
  AXE83_RS08350 (AXE83_08350) trpC 1782903..1783670 (-) 768 WP_060956115.1 indole-3-glycerol phosphate synthase TrpC -
  AXE83_RS08355 (AXE83_08355) trpD 1783667..1784671 (-) 1005 WP_006146009.1 anthranilate phosphoribosyltransferase -
  AXE83_RS08360 (AXE83_08360) - 1784682..1785248 (-) 567 WP_060956116.1 aminodeoxychorismate/anthranilate synthase component II -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25166.62 Da        Isoelectric Point: 7.8750

>NTDB_id=170015 AXE83_RS08330 WP_060956111.1 1779710..1780372(+) (cclA/cilC) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
MIHLYFFLVGAIIASFIGLVIDRFPEQSIIFPASHCDSCHTRLHPLDLIPIISQVVYRFRCRYCKSNYPVWYTLFELFLG
LLFLTFSLGFLTLNQVILIAAGLTLGIYDFRHQEYPLLVWLTFHLFLIVCCGWNLVMIFFLILGILAHFIDIRIGAGDFL
FLASCALIFSLTEMLILIQFASTTGILAFLLLKKKERLPFVPFLLLAACMIIFGKLLLLG

Nucleotide


Download         Length: 663 bp        

>NTDB_id=170015 AXE83_RS08330 WP_060956111.1 1779710..1780372(+) (cclA/cilC) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
ATGATTCATCTTTACTTTTTTCTTGTTGGAGCTATTATTGCTTCCTTTATAGGTCTTGTCATTGACCGCTTTCCTGAGCA
GTCTATTATCTTTCCTGCTAGTCACTGCGATTCCTGTCATACTCGCTTACATCCCTTGGATTTGATTCCAATTATTTCTC
AAGTAGTCTATCGCTTTCGCTGTCGCTACTGCAAGTCAAACTATCCTGTCTGGTATACCCTCTTTGAGTTATTCTTGGGG
CTACTCTTTCTAACTTTTTCTTTGGGATTTCTAACTTTGAATCAAGTCATTTTGATCGCCGCTGGCTTGACCTTAGGCAT
CTACGACTTTCGTCATCAAGAATATCCCTTGCTAGTCTGGCTGACTTTTCACTTATTCCTCATAGTTTGCTGTGGTTGGA
ATCTAGTTATGATTTTCTTTCTTATCTTGGGAATTTTGGCTCACTTTATCGATATCCGCATAGGTGCTGGAGATTTTCTC
TTTCTGGCTTCTTGTGCACTTATTTTTAGCCTAACTGAAATGCTGATTTTAATTCAATTTGCTTCCACGACTGGTATCCT
AGCCTTTCTCCTACTAAAGAAAAAGGAAAGACTACCTTTTGTGCCTTTCCTCTTACTGGCTGCTTGTATGATTATTTTTG
GTAAGCTACTGCTTCTCGGATAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-87)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0X8JZ76

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

81.735

99.545

0.814
  cclA/cilC Streptococcus pneumoniae Rx1

81.735

99.545

0.814
  cclA/cilC Streptococcus pneumoniae D39

81.735

99.545

0.814
  cclA/cilC Streptococcus pneumoniae R6

81.735

99.545

0.814
  cclA/cilC Streptococcus pneumoniae TIGR4

80.365

99.545

0.8
  cclA/cilC Streptococcus mitis NCTC 12261

79.909

99.545

0.795

Multiple sequence alignment