Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   AXE83_RS00065 Genome accession   NZ_CP014264
Coordinates   15202..16500 (-) Length   432 a.a.
NCBI ID   WP_060954957.1    Uniprot ID   A0A0X8JWB2
Organism   Streptococcus sp. oral taxon 431 strain F0610 (5-114)     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 10202..21500
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AXE83_RS00045 (AXE83_00045) rplI 11350..11802 (-) 453 WP_000864204.1 50S ribosomal protein L9 -
  AXE83_RS00050 (AXE83_00050) - 11799..13772 (-) 1974 WP_060954955.1 DHH family phosphoesterase -
  AXE83_RS00055 (AXE83_00055) raiA 13921..14463 (-) 543 WP_045762429.1 ribosome-associated translation inhibitor RaiA -
  AXE83_RS00060 (AXE83_00060) comFC/cflB 14543..15205 (-) 663 WP_060954956.1 ComF family protein Machinery gene
  AXE83_RS00065 (AXE83_00065) comFA/cflA 15202..16500 (-) 1299 WP_060954957.1 DEAD/DEAH box helicase Machinery gene
  AXE83_RS00070 (AXE83_00070) - 16556..17191 (+) 636 WP_060954958.1 YigZ family protein -
  AXE83_RS00075 (AXE83_00075) - 17208..17651 (+) 444 WP_060954959.1 PH domain-containing protein -
  AXE83_RS00080 (AXE83_00080) cysK 17748..18674 (+) 927 WP_060954960.1 cysteine synthase A -
  AXE83_RS00085 (AXE83_00085) tsf 18789..19829 (-) 1041 WP_060954961.1 translation elongation factor Ts -
  AXE83_RS00090 (AXE83_00090) rpsB 19909..20691 (-) 783 WP_000268462.1 30S ribosomal protein S2 -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49480.30 Da        Isoelectric Point: 8.6202

>NTDB_id=169968 AXE83_RS00065 WP_060954957.1 15202..16500(-) (comFA/cflA) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
MKVNPNYLGRLFTEQELSHEERQQAKQIPSMQKEKGQLSCQRCGSQIEEEWHLPIGAFYCRECLIMKRIRSDQNLYYFPQ
ERFPQQDVLKWLGQLTPFQERVSQGLLQAVDKKEATLVHAVTGAGKTEMIYQVVAKVIDQGGAVCLASPRIDVCLELHKR
LQNDFACEIALLHGESDPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPVLYHAVNNCVKETGLRIFLTATST
DELDRKVKQGELKRLSLPRRFHGNPLIVPKPIWLSHFNRYLEKNGLPPKLKLYIEKQRKTAYPLLIFASEIKKGEKLKEI
LQAKFPNEKIGFVSSITEDRLDQVQAFRDGELTILISTTILERGVTFPRVDVFVVEANHQLFTKSSLVQIGGRVGRSMDR
PTGELIFFHDGLNLSIKKAIKEIKQMNQEAGV

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=169968 AXE83_RS00065 WP_060954957.1 15202..16500(-) (comFA/cflA) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
ATGAAAGTAAATCCAAATTATCTCGGTCGCCTTTTTACCGAGCAAGAATTAAGTCATGAGGAGAGACAACAAGCAAAACA
AATTCCATCCATGCAAAAAGAAAAGGGGCAACTATCTTGTCAGCGTTGTGGTAGTCAGATAGAAGAAGAATGGCATTTGC
CTATTGGTGCTTTTTATTGCCGAGAATGCTTGATTATGAAGCGAATAAGAAGTGATCAAAATCTCTATTATTTTCCGCAA
GAAAGGTTTCCACAGCAAGATGTACTAAAATGGTTAGGTCAACTGACTCCATTTCAAGAGCGGGTATCACAAGGACTCCT
TCAGGCGGTAGATAAGAAGGAGGCTACCTTGGTACATGCAGTGACAGGAGCTGGTAAGACAGAGATGATTTACCAAGTTG
TTGCCAAGGTAATTGATCAAGGTGGAGCTGTTTGTTTGGCCAGTCCACGAATTGATGTTTGCCTAGAACTCCATAAACGA
TTACAAAATGATTTTGCATGTGAGATTGCACTATTACATGGGGAGTCGGATCCGTATTTTCGTACACCTTTAGTTGTAGC
AACCACTCACCAGCTATTAAAATTTTATCAAGCTTTTGATTTATTGATTGTGGATGAAGTAGACGCCTTCCCTTATGTTG
ATAATCCTGTACTTTACCATGCTGTCAATAATTGTGTAAAGGAGACCGGATTGAGAATATTTTTAACAGCAACGTCAACT
GATGAGTTAGATAGAAAAGTTAAACAAGGGGAGTTAAAGCGTCTTAGTTTACCTCGTCGTTTTCATGGAAATCCTCTTAT
TGTCCCCAAGCCAATCTGGTTATCGCATTTTAATAGATATTTAGAAAAAAATGGCTTACCTCCAAAATTAAAACTTTACA
TTGAGAAACAGAGAAAGACGGCCTATCCCTTACTAATCTTTGCCTCTGAGATTAAAAAGGGAGAAAAGCTAAAAGAAATT
TTGCAGGCGAAGTTTCCGAATGAGAAAATAGGATTTGTATCTTCAATCACAGAAGACCGATTAGATCAGGTACAGGCCTT
TCGAGATGGAGAGTTGACGATATTAATAAGCACAACTATATTAGAGCGTGGAGTTACCTTCCCTCGTGTAGATGTTTTTG
TGGTGGAAGCCAATCATCAACTCTTTACCAAGTCAAGTTTAGTACAAATTGGTGGGCGAGTTGGAAGAAGCATGGATCGT
CCTACCGGAGAACTGATATTTTTCCATGACGGACTCAATCTGTCCATTAAGAAAGCCATAAAGGAGATTAAGCAAATGAA
TCAGGAGGCAGGAGTATGA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(94-238)

Helicase conserved C-terminal domain (Helicase_C)

(294-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0X8JWB2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

84.954

100

0.85
  comFA/cflA Streptococcus pneumoniae Rx1

84.491

100

0.845
  comFA/cflA Streptococcus pneumoniae D39

84.491

100

0.845
  comFA/cflA Streptococcus pneumoniae R6

84.491

100

0.845
  comFA/cflA Streptococcus mitis SK321

84.259

100

0.843
  comFA/cflA Streptococcus pneumoniae TIGR4

84.259

100

0.843
  comFA Lactococcus lactis subsp. cremoris KW2

52.645

91.898

0.484
  comFA Latilactobacillus sakei subsp. sakei 23K

39.211

99.769

0.391
  comFA Bacillus subtilis subsp. subtilis str. 168

38.049

94.907

0.361

Multiple sequence alignment