Detailed information NTG0169033

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: BIZ52_RS06170
• Genome accession: NZ_CP017457
• Coordinates: 1367742..1368419 (-)
• Length: 225 a.a.
• NCBI ID: WP_011213604.1
• Uniprot ID: -
• Organism: Legionella pneumophila subsp. fraseri strain Detroit-1
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 1362742..1373419

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BIZ52_RS06145 (BIZ52_06070)	ruvC	1362905..1363429 (+)	525	WP_027226814.1	crossover junction endodeoxyribonuclease RuvC	-
BIZ52_RS06150 (BIZ52_06075)	ruvA	1363426..1364025 (+)	600	WP_027226815.1	Holliday junction branch migration protein RuvA	Machinery gene
BIZ52_RS06155 (BIZ52_06080)	-	1364084..1364404 (+)	321	WP_027226816.1	hypothetical protein	-
BIZ52_RS06160 (BIZ52_06085)	lem8	1364482..1366041 (-)	1560	WP_027226817.1	Dot/Icm T4SS effector Lem8	-
BIZ52_RS06165 (BIZ52_06090)	-	1366330..1367745 (-)	1416	WP_027226818.1	ATP-binding protein	-
BIZ52_RS06170 (BIZ52_06095)	ciaR	1367742..1368419 (-)	678	WP_011213604.1	response regulator	Regulator
BIZ52_RS06175 (BIZ52_06100)	-	1368480..1369025 (-)	546	WP_027221489.1	septation protein A	-
BIZ52_RS06180 (BIZ52_06105)	-	1369269..1370708 (-)	1440	WP_027226819.1	LysM peptidoglycan-binding domain-containing protein	-
BIZ52_RS06185 (BIZ52_06110)	gloB	1370822..1371586 (-)	765	WP_027226820.1	hydroxyacylglutathione hydrolase	-
BIZ52_RS06190 (BIZ52_06115)	-	1371590..1372438 (-)	849	WP_027226821.1	23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ	-
BIZ52_RS06195 (BIZ52_06120)	-	1372577..1372786 (+)	210	WP_011213609.1	hypothetical protein	-

Sequence

Protein

• Length: 225 a.a.
• Molecular weight: 25151.74 Da
• Isoelectric Point: 4.9981

>NTDB_id=169033 BIZ52_RS06170 WP_011213604.1 1367742..1368419(-) (ciaR) [Legionella pneumophila subsp. fraseri strain Detroit-1]
MRLLLVEDDELLGDAVKAGLTQFGYVVDWLKDGEAARAALKSESFELIILDLGLPKLSGLSLLQNIRHDGNSTPVIILTA
RESIEDRVKGLDSGADDYLIKPFDLNELSARIRALVRRSQGRADSVLQYKNITLDPAAHSVFVDDVLVNVPRREFALLQK
LLENSGQVLSREQLMQSIYGWEEDVDSNALEVHIHNLRKKLNANFIRTIRGVGYMAEKNDSVLLS

Nucleotide

• Length: 678 bp

>NTDB_id=169033 BIZ52_RS06170 WP_011213604.1 1367742..1368419(-) (ciaR) [Legionella pneumophila subsp. fraseri strain Detroit-1]
ATGAGATTATTACTTGTTGAAGACGATGAACTGCTTGGTGATGCAGTAAAAGCCGGATTGACACAATTTGGGTATGTTGT
TGACTGGCTAAAAGATGGCGAAGCTGCGCGAGCAGCTCTCAAATCAGAGTCTTTTGAATTAATTATTCTTGACTTGGGAT
TACCTAAATTATCCGGTTTATCATTATTACAAAACATCAGACATGATGGAAATTCCACACCTGTCATTATTCTTACAGCT
CGAGAATCAATAGAAGATCGAGTAAAAGGTTTAGATAGTGGCGCTGACGATTATCTTATTAAACCTTTTGATTTAAACGA
ATTAAGTGCAAGGATTAGAGCCTTGGTAAGGCGCTCTCAGGGTAGAGCTGATTCAGTGTTGCAATATAAAAATATTACCC
TTGATCCAGCCGCTCATTCTGTATTCGTGGATGATGTTCTCGTCAATGTTCCAAGAAGAGAATTCGCTCTATTGCAGAAA
TTACTTGAAAACAGTGGTCAAGTCTTATCTCGAGAACAATTAATGCAGAGTATTTATGGTTGGGAAGAAGACGTGGACAG
CAATGCTCTTGAGGTTCATATCCATAATTTACGTAAAAAACTTAATGCAAACTTTATCCGCACTATTCGTGGTGTAGGAT
ATATGGCTGAAAAAAATGACAGTGTACTTCTATCGTGA

Domains

Predicted by InterProScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (148-215)

• Response regulator receiver domain (Response_reg) (4-113)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus pneumoniae Rx1	38.356	97.333	0.373
ciaR	Streptococcus pneumoniae D39	38.356	97.333	0.373
ciaR	Streptococcus pneumoniae R6	38.356	97.333	0.373
ciaR	Streptococcus pneumoniae TIGR4	38.356	97.333	0.373
ciaR	Streptococcus mutans UA159	37.9	97.333	0.369
micA	Streptococcus pneumoniae Cp1015	35.345	100	0.364