Detailed information NTG0168751

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: AWB63_RS07520
• Genome accession: NZ_CP014144
• Coordinates: 1663118..1665358 (+)
• Length: 746 a.a.
• NCBI ID: WP_038676610.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain JF
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1658118..1670358

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AWB63_RS07495 (AWB63_07495)	-	1659417..1659686 (-)	270	WP_060775884.1	GIY-YIG nuclease family protein	-
AWB63_RS07500 (AWB63_07500)	-	1659690..1660454 (-)	765	WP_038676615.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
AWB63_RS07505 (AWB63_07505)	-	1660504..1661439 (-)	936	WP_052124418.1	polysaccharide deacetylase family protein	-
AWB63_RS07510 (AWB63_07510)	-	1661569..1662324 (+)	756	WP_022496132.1	lysophospholipid acyltransferase family protein	-
AWB63_RS07515 (AWB63_07515)	comEA	1662433..1663128 (+)	696	WP_022496133.1	helix-hairpin-helix domain-containing protein	Machinery gene
AWB63_RS07520 (AWB63_07520)	comEC/celB	1663118..1665358 (+)	2241	WP_038676610.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
AWB63_RS07525 (AWB63_07525)	-	1665444..1666706 (+)	1263	WP_002884638.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
AWB63_RS07530 (AWB63_07530)	-	1666772..1667317 (+)	546	WP_013991031.1	GNAT family N-acetyltransferase	-
AWB63_RS07535 (AWB63_07535)	spxR	1667310..1668590 (+)	1281	WP_060775885.1	CBS-HotDog domain-containing transcription factor SpxR	-
AWB63_RS07540 (AWB63_07540)	-	1668635..1669495 (+)	861	WP_002884335.1	methionyl aminopeptidase	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84420.30 Da
• Isoelectric Point: 9.9046

>NTDB_id=168751 AWB63_RS07520 WP_038676610.1 1663118..1665358(+) (comEC/celB) [Streptococcus salivarius strain JF]
MWLKKAPINLFSLALLIAALYFTIFNTNVYAIGVLSFLLGCFLKHHWKNKVALKLVGLVGSFFLVYFLFLHHRATIQDKQ
APTEINQVTLVADTLSVNGEQLSAIGKAKGQTYQVFYRLKSEKEQHFFKTTSQTLVLKGKIKLSLAIGQRNFQGFNYQSY
LASQGIYRMAQIERLDHVVPQKSLSPLAFFHQLRRRALVHIQTHFPSPMRHYMTGLLFGYLGKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKDYLFIILLPFSLCYGLMTGWTASVLRSLIQSLLAEFGIKKLDNMGITLLLLFLF
LPHFLLTVGGVLSCSYAFLLCLFDFEEMSSLKKSICTSLVLSLGILPFLTFYYGTFQPVSLILTAMFSIVFDSFLLPVLT
VFFALSGLVIFSQINPLFEWMEAFLTWIQSWIGQPLILGKPSLFQFGLMIAVLVMLFDFWKKPQFRICLLMIFGLLMVWV
KHPLTNEVTMVDVGQGDSIFLRSMKGDTILIDVGGKVTFGSKEKWQEASQTSNAEKTLIPYLQARGVSQIDHLVLTHTDT
DHIGDLEEVAKRFKIKEICVSQGALTKPSFVKRLRTLKRPVRTLKAGDNLPMMGSKLQVLYPNKVGDGGNNDSIVLYGKL
LGSSFLFTGDLEKEGEEELMVSYPNLKASVLKAGHHGSKGSSSEAFLDQLQPSLALVSAGENNRYKHPNDETLERFKERH
IKVLRTDQNGAIRFKGWFKWSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=168751 AWB63_RS07520 WP_038676610.1 1663118..1665358(+) (comEC/celB) [Streptococcus salivarius strain JF]
ATGTGGCTTAAAAAAGCTCCAATCAATCTTTTTTCCTTGGCTCTGTTAATAGCTGCCCTTTATTTTACGATTTTTAACAC
AAATGTTTATGCTATTGGGGTTTTGTCTTTTCTTTTAGGATGTTTTTTGAAGCATCATTGGAAGAATAAGGTAGCCCTAA
AGTTGGTGGGACTTGTAGGTAGTTTCTTTTTGGTCTACTTTTTATTCTTGCACCACAGAGCTACCATACAAGATAAACAA
GCTCCTACTGAAATCAATCAGGTGACTCTGGTTGCTGATACGCTGTCGGTTAATGGTGAGCAATTATCAGCTATTGGAAA
GGCAAAGGGACAAACTTATCAGGTCTTTTACCGACTCAAATCTGAGAAGGAGCAGCATTTTTTTAAGACTACTAGCCAAA
CGTTGGTATTAAAAGGGAAAATAAAGTTATCCCTAGCAATTGGTCAACGTAATTTTCAAGGGTTTAATTATCAGTCTTAT
CTAGCCAGTCAAGGCATTTATCGAATGGCTCAGATTGAACGCTTGGACCATGTGGTGCCTCAAAAATCTCTATCTCCCCT
AGCTTTTTTCCATCAACTGAGGAGGAGGGCATTGGTTCATATCCAGACGCACTTTCCTAGTCCTATGAGACACTATATGA
CAGGTCTGCTCTTTGGGTATTTGGGTAAGGAGTTTGATGAGCAAAGTCAGCTTTACACAAGCTTAGGTATTATTCATCTA
TTCGCACTTTCGGGGATGCAAGTGGGCTTTTTTCTGGGATGGTTTCGCTATGGACTCCTACGCTTGGGCCTTCCTAAAGA
TTATCTATTTATTATCTTGCTGCCTTTTTCCTTGTGTTATGGCTTAATGACAGGTTGGACAGCTTCAGTCCTACGTTCCC
TGATTCAAAGTTTGTTAGCGGAGTTTGGTATTAAAAAACTGGATAATATGGGGATAACTTTGCTTCTATTGTTTCTCTTT
TTACCTCATTTTCTTTTGACAGTGGGAGGTGTTTTAAGTTGTTCCTATGCCTTTTTGTTGTGTTTGTTTGATTTTGAGGA
GATGTCATCTCTTAAAAAGTCAATCTGTACGAGCTTAGTGTTGAGTCTTGGGATTTTGCCTTTTCTAACTTTCTATTATG
GGACCTTTCAACCGGTGAGTTTAATTCTGACGGCGATGTTTTCGATAGTATTTGATAGCTTTCTCTTGCCTGTATTGACA
GTCTTCTTTGCTCTTTCAGGACTGGTAATCTTTTCTCAAATCAACCCACTTTTTGAATGGATGGAGGCCTTTTTGACTTG
GATACAATCCTGGATAGGCCAGCCTTTGATTTTAGGGAAACCTAGTTTGTTTCAGTTTGGCTTGATGATAGCTGTCTTGG
TTATGCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGGATTTGCCTTTTGATGATTTTTGGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAACCAATGAGGTGACTATGGTTGACGTTGGTCAGGGAGATAGTATTTTTCTGAGGAGTATGAAAGGCGA
TACCATCCTAATTGATGTGGGTGGCAAGGTGACTTTCGGGTCAAAGGAAAAATGGCAAGAGGCTAGCCAGACGAGCAATG
CGGAGAAAACCTTGATTCCCTACCTACAGGCTAGGGGAGTGTCTCAAATTGACCATCTGGTCCTGACTCATACGGATACA
GACCATATTGGTGATTTGGAAGAAGTAGCCAAGCGGTTTAAGATTAAGGAAATCTGTGTCAGTCAAGGAGCTTTGACTAA
GCCTAGTTTTGTGAAACGACTTCGAACTTTAAAACGCCCAGTTCGCACTCTAAAGGCTGGAGACAACTTACCCATGATGG
GAAGTAAGCTACAGGTTCTTTATCCAAATAAAGTTGGTGATGGTGGTAACAACGATTCGATAGTTCTTTACGGAAAACTA
TTAGGAAGTAGTTTTTTGTTTACGGGTGATCTAGAAAAAGAAGGAGAGGAGGAACTGATGGTCAGCTATCCTAATTTAAA
GGCTAGTGTCCTCAAAGCCGGACACCACGGTTCAAAAGGGTCATCGTCTGAAGCGTTTTTGGACCAGTTGCAGCCCTCCC
TTGCCCTTGTTTCAGCTGGTGAGAATAATCGTTATAAACATCCAAATGATGAAACTTTGGAGCGTTTCAAGGAACGTCAC
ATTAAGGTTTTACGAACAGACCAGAACGGTGCTATCCGTTTTAAGGGGTGGTTTAAGTGGTCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterproScan.

• Competence protein (Competence) (216-462)

• Domain of unknown function (DUF4131) (DUF4131) (29-169)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-699)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	48.594	100	0.487
comEC/celB	Streptococcus mitis SK321	48.262	100	0.484
comEC/celB	Streptococcus pneumoniae Rx1	47.193	100	0.473
comEC/celB	Streptococcus pneumoniae D39	47.193	100	0.473
comEC/celB	Streptococcus pneumoniae R6	47.193	100	0.473
comEC/celB	Streptococcus pneumoniae TIGR4	47.059	100	0.472
comEC	Lactococcus lactis subsp. cremoris KW2	43.514	99.196	0.432