Detailed information NTG0168252

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AL519_RS10270
• Genome accession: NZ_CP014064
• Coordinates: 1878285..1879172 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain FDAARGOS_159
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1873285..1884172

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AL519_RS10235 (AL519_10020)	-	1873304..1873396 (+)	93	WP_010956583.1	hypothetical protein	-
AL519_RS10240 (AL519_10025)	-	1873504..1874001 (-)	498	WP_001065268.1	glutathione peroxidase	-
AL519_RS10245 (AL519_10030)	-	1874011..1874271 (-)	261	WP_001791974.1	hypothetical protein	-
AL519_RS10255 (AL519_10035)	-	1874653..1874766 (-)	114	Protein_1870	hypothetical protein	-
AL519_RS10260 (AL519_10045)	-	1875425..1877425 (-)	2001	WP_000776751.1	ABC transporter permease	-
AL519_RS10265 (AL519_10050)	-	1877422..1878177 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AL519_RS10270 (AL519_10055)	braS	1878285..1879172 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AL519_RS10275 (AL519_10060)	braR	1879183..1879848 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AL519_RS10280 (AL519_10065)	-	1879874..1880074 (-)	201	WP_000604730.1	hypothetical protein	-
AL519_RS10285 (AL519_10075)	-	1880272..1881696 (+)	1425	WP_000953755.1	alkaline phosphatase	-
AL519_RS15125 (AL519_14875)	-	1881756..1881857 (-)	102	WP_000731976.1	SE2200 family small protein	-
AL519_RS10295 (AL519_10080)	-	1881979..1882434 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AL519_RS10300 (AL519_10085)	-	1882679..1883440 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=168252 AL519_RS10270 WP_000143425.1 1878285..1879172(-) (braS) [Staphylococcus aureus strain FDAARGOS_159]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=168252 AL519_RS10270 WP_000143425.1 1878285..1879172(-) (braS) [Staphylococcus aureus strain FDAARGOS_159]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTTACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1