Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   AL519_RS06960 Genome accession   NZ_CP014064
Coordinates   1259457..1260173 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain FDAARGOS_159     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1254457..1265173
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AL519_RS06930 (AL519_06820) - 1254674..1255300 (+) 627 WP_000522381.1 nitroreductase family protein -
  AL519_RS06935 (AL519_06825) - 1255661..1256446 (+) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  AL519_RS15105 hld 1257046..1257126 (-) 81 WP_000046022.1 delta-hemolysin -
  AL519_RS06945 (AL519_06835) - 1257416..1257979 (+) 564 WP_001105696.1 accessory gene regulator AgrB -
  AL519_RS06950 (AL519_06840) agrD 1257982..1258125 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  AL519_RS06955 (AL519_06845) agrC 1258155..1259438 (+) 1284 WP_000447888.1 quorum-sensing sensor histidine kinase AgrC -
  AL519_RS06960 (AL519_06850) agrA 1259457..1260173 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  AL519_RS06965 (AL519_06855) - 1260245..1260354 (+) 110 Protein_1260 hypothetical protein -
  AL519_RS06970 (AL519_06860) - 1260542..1261501 (-) 960 WP_001253312.1 carbohydrate kinase family protein -
  AL519_RS06975 (AL519_06865) - 1261498..1262982 (-) 1485 WP_000141431.1 sucrose-6-phosphate hydrolase -
  AL519_RS06980 (AL519_06870) - 1263131..1264081 (-) 951 WP_000790331.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=168248 AL519_RS06960 WP_000688492.1 1259457..1260173(+) (agrA) [Staphylococcus aureus strain FDAARGOS_159]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=168248 AL519_RS06960 WP_000688492.1 1259457..1260173(+) (agrA) [Staphylococcus aureus strain FDAARGOS_159]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment