Detailed information
Bioinformatically predicted
Overview
| Name | prx | Type | Regulator |
| Locus tag | AL510_RS06125 | Genome accession | NZ_CP014027 |
| Coordinates | 1195128..1195307 (+) | Length | 59 a.a. |
| NCBI ID | WP_002988813.1 | Uniprot ID | Q5YAB1 |
| Organism | Streptococcus pyogenes strain FDAARGOS_149 | ||
| Function | Inhibit ComR activation (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 1154691..1200908 | 1195128..1195307 | within | 0 |
Gene organization within MGE regions
Location: 1154691..1200908
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AL510_RS05875 (AL510_05695) | - | 1154691..1155770 (-) | 1080 | WP_002988667.1 | site-specific integrase | - |
| AL510_RS05880 (AL510_05700) | - | 1155887..1156438 (-) | 552 | WP_002988670.1 | hypothetical protein | - |
| AL510_RS05885 (AL510_05705) | - | 1156449..1156832 (-) | 384 | WP_002988673.1 | ImmA/IrrE family metallo-endopeptidase | - |
| AL510_RS05890 (AL510_05710) | - | 1156846..1157196 (-) | 351 | WP_002988676.1 | helix-turn-helix domain-containing protein | - |
| AL510_RS05895 (AL510_05715) | - | 1157657..1158070 (-) | 414 | WP_002988681.1 | hypothetical protein | - |
| AL510_RS05900 (AL510_05720) | - | 1158118..1158333 (+) | 216 | WP_002988684.1 | hypothetical protein | - |
| AL510_RS05905 (AL510_05725) | - | 1158395..1158670 (+) | 276 | WP_002988687.1 | hypothetical protein | - |
| AL510_RS05910 (AL510_09480) | - | 1158667..1158837 (+) | 171 | WP_002988693.1 | hypothetical protein | - |
| AL510_RS05915 (AL510_05730) | - | 1158830..1159033 (+) | 204 | WP_002988697.1 | hypothetical protein | - |
| AL510_RS05920 (AL510_05735) | - | 1159030..1159416 (+) | 387 | WP_002988700.1 | hypothetical protein | - |
| AL510_RS09525 | - | 1159413..1159565 (+) | 153 | WP_011285675.1 | hypothetical protein | - |
| AL510_RS05925 (AL510_05740) | - | 1159562..1159765 (+) | 204 | WP_002988705.1 | hypothetical protein | - |
| AL510_RS05930 (AL510_05745) | - | 1159853..1160152 (+) | 300 | WP_002988708.1 | hypothetical protein | - |
| AL510_RS05935 (AL510_05750) | - | 1160152..1161306 (+) | 1155 | WP_002988711.1 | DUF2800 domain-containing protein | - |
| AL510_RS05940 (AL510_05755) | - | 1161310..1161708 (+) | 399 | WP_002988715.1 | hypothetical protein | - |
| AL510_RS05945 (AL510_05760) | - | 1161719..1162276 (+) | 558 | WP_002988718.1 | DUF2815 family protein | - |
| AL510_RS05950 (AL510_05765) | - | 1162319..1164241 (+) | 1923 | WP_032463529.1 | DNA polymerase | - |
| AL510_RS05955 (AL510_05770) | - | 1164246..1166630 (+) | 2385 | WP_011285674.1 | phage/plasmid primase, P4 family | - |
| AL510_RS05960 (AL510_05775) | - | 1167017..1167292 (+) | 276 | WP_002988730.1 | VRR-NUC domain-containing protein | - |
| AL510_RS05965 (AL510_05780) | - | 1167289..1168611 (+) | 1323 | WP_002988733.1 | SNF2-related protein | - |
| AL510_RS09530 | - | 1168612..1168779 (+) | 168 | WP_002988735.1 | hypothetical protein | - |
| AL510_RS05970 (AL510_05785) | - | 1168776..1169042 (+) | 267 | WP_002988738.1 | hypothetical protein | - |
| AL510_RS05975 (AL510_05790) | - | 1169051..1169761 (+) | 711 | WP_050428439.1 | DNA-methyltransferase | - |
| AL510_RS05980 (AL510_05795) | - | 1169893..1170084 (+) | 192 | WP_002988743.1 | hypothetical protein | - |
| AL510_RS05985 (AL510_05800) | - | 1170081..1170497 (+) | 417 | WP_002988747.1 | DUF722 domain-containing protein | - |
| AL510_RS05990 (AL510_05805) | - | 1170587..1171039 (+) | 453 | WP_011106637.1 | terminase small subunit | - |
| AL510_RS05995 (AL510_05810) | - | 1171029..1172306 (+) | 1278 | WP_002988754.1 | PBSX family phage terminase large subunit | - |
| AL510_RS06000 (AL510_05815) | - | 1172322..1173854 (+) | 1533 | WP_002988758.1 | phage portal protein | - |
| AL510_RS06005 (AL510_05820) | - | 1173814..1175259 (+) | 1446 | WP_015446273.1 | minor capsid protein | - |
| AL510_RS06010 (AL510_05825) | - | 1175290..1175478 (+) | 189 | WP_002983423.1 | hypothetical protein | - |
| AL510_RS06015 (AL510_05830) | - | 1175481..1175747 (+) | 267 | WP_002988765.1 | hypothetical protein | - |
| AL510_RS06020 (AL510_05835) | - | 1175903..1176472 (+) | 570 | WP_002988768.1 | DUF4355 domain-containing protein | - |
| AL510_RS06025 (AL510_05840) | - | 1176485..1177372 (+) | 888 | WP_002988771.1 | hypothetical protein | - |
| AL510_RS06030 (AL510_05845) | - | 1177384..1177740 (+) | 357 | WP_002988776.1 | phage head-tail connector protein | - |
| AL510_RS06035 (AL510_05850) | - | 1177751..1178029 (+) | 279 | WP_000639437.1 | hypothetical protein | - |
| AL510_RS06040 (AL510_05855) | - | 1178026..1178370 (+) | 345 | WP_002988781.1 | HK97-gp10 family putative phage morphogenesis protein | - |
| AL510_RS06045 (AL510_05860) | - | 1178374..1178733 (+) | 360 | WP_002988782.1 | hypothetical protein | - |
| AL510_RS06050 (AL510_05865) | - | 1178745..1179344 (+) | 600 | WP_002988784.1 | phage major tail protein, TP901-1 family | - |
| AL510_RS06055 (AL510_05870) | - | 1179398..1179853 (+) | 456 | WP_002983443.1 | tail assembly chaperone | - |
| AL510_RS06060 (AL510_05875) | - | 1179928..1180161 (+) | 234 | WP_002983445.1 | hypothetical protein | - |
| AL510_RS06065 (AL510_05880) | - | 1180176..1184558 (+) | 4383 | WP_002988786.1 | tape measure protein | - |
| AL510_RS06070 (AL510_05885) | - | 1184570..1185412 (+) | 843 | WP_002988788.1 | phage tail family protein | - |
| AL510_RS06075 (AL510_05890) | - | 1185422..1187404 (+) | 1983 | WP_002988790.1 | phage tail protein | - |
| AL510_RS06080 (AL510_05895) | - | 1187401..1188456 (+) | 1056 | WP_002988439.1 | hypothetical protein | - |
| AL510_RS06085 (AL510_05900) | - | 1188456..1189091 (+) | 636 | WP_002988442.1 | hypothetical protein | - |
| AL510_RS06090 (AL510_05905) | - | 1189102..1191009 (+) | 1908 | WP_002988792.1 | gp58-like family protein | - |
| AL510_RS06095 (AL510_09485) | - | 1191018..1191179 (+) | 162 | WP_002988795.1 | hypothetical protein | - |
| AL510_RS06100 (AL510_05910) | - | 1191182..1191802 (+) | 621 | WP_002988797.1 | hypothetical protein | - |
| AL510_RS06105 (AL510_05915) | - | 1191813..1192112 (+) | 300 | WP_002988799.1 | hypothetical protein | - |
| AL510_RS06110 (AL510_05920) | - | 1192109..1192294 (+) | 186 | WP_002988802.1 | holin | - |
| AL510_RS06115 (AL510_05925) | - | 1192405..1193601 (+) | 1197 | WP_002988807.1 | glucosaminidase domain-containing protein | - |
| AL510_RS06120 (AL510_05930) | sda1 | 1193717..1194889 (-) | 1173 | WP_002988811.1 | streptodornase Sda1 | - |
| AL510_RS06125 (AL510_05935) | prx | 1195128..1195307 (+) | 180 | WP_002988813.1 | hypothetical protein | Regulator |
| AL510_RS06130 (AL510_05940) | rimP | 1195552..1196088 (+) | 537 | WP_002988815.1 | ribosome maturation factor RimP | - |
| AL510_RS06135 (AL510_05945) | nusA | 1196263..1197420 (+) | 1158 | WP_002988817.1 | transcription termination factor NusA | - |
| AL510_RS06140 (AL510_05950) | rnpM | 1197436..1197732 (+) | 297 | WP_002983486.1 | RNase P modulator RnpM | - |
| AL510_RS06145 (AL510_05955) | - | 1197725..1198027 (+) | 303 | WP_002983488.1 | YlxQ-related RNA-binding protein | - |
| AL510_RS06150 (AL510_05960) | infB | 1198047..1200908 (+) | 2862 | WP_002983491.1 | translation initiation factor IF-2 | - |
Sequence
Protein
Download Length: 59 a.a. Molecular weight: 6798.70 Da Isoelectric Point: 4.2542
>NTDB_id=167525 AL510_RS06125 WP_002988813.1 1195128..1195307(+) (prx) [Streptococcus pyogenes strain FDAARGOS_149]
MLTYDEFKQAIDHGYITGDTVAIVRKNGQIFDYVLPHEKVKNGEVVTDEKVEEVLMELE
MLTYDEFKQAIDHGYITGDTVAIVRKNGQIFDYVLPHEKVKNGEVVTDEKVEEVLMELE
Nucleotide
Download Length: 180 bp
>NTDB_id=167525 AL510_RS06125 WP_002988813.1 1195128..1195307(+) (prx) [Streptococcus pyogenes strain FDAARGOS_149]
ATGCTAACATACGACGAATTTAAGCAAGCAATCGACCATGGGTATATCACAGGAGACACAGTAGCGATTGTGCGCAAAAA
CGGACAGATCTTTGATTATGTGTTGCCACATGAGAAAGTAAAGAATGGAGAAGTTGTGACAGATGAAAAAGTGGAAGAAG
TGTTGATGGAATTGGAGTAA
ATGCTAACATACGACGAATTTAAGCAAGCAATCGACCATGGGTATATCACAGGAGACACAGTAGCGATTGTGCGCAAAAA
CGGACAGATCTTTGATTATGTGTTGCCACATGAGAAAGTAAAGAATGGAGAAGTTGTGACAGATGAAAAAGTGGAAGAAG
TGTTGATGGAATTGGAGTAA
Domains
No domain identified.
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| prx | Streptococcus pyogenes MGAS8232 |
91.379 |
98.305 |
0.898 |
| prx | Streptococcus pyogenes MGAS315 |
87.931 |
98.305 |
0.864 |
| prx | Streptococcus pyogenes MGAS315 |
84.746 |
100 |
0.847 |
| prx | Streptococcus pyogenes MGAS315 |
74.576 |
100 |
0.746 |
| prx | Streptococcus pyogenes MGAS315 |
86.047 |
72.881 |
0.627 |
| prx | Streptococcus pyogenes MGAS315 |
90.244 |
69.492 |
0.627 |
| prx | Streptococcus pyogenes MGAS315 |
80.952 |
71.186 |
0.576 |