Detailed information NTG0167507

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: AL510_RS03670
• Genome accession: NZ_CP014027
• Coordinates: 712604..713515 (-)
• Length: 303 a.a.
• NCBI ID: WP_002986681.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain FDAARGOS_149
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 707604..718515

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AL510_RS03650 (AL510_03540)	-	708609..710384 (-)	1776	WP_010921782.1	acyltransferase family protein	-
AL510_RS03655 (AL510_03545)	-	710381..710782 (-)	402	WP_010921781.1	MORN repeat-containing protein	-
AL510_RS03660 (AL510_03550)	-	710805..711242 (-)	438	WP_002994668.1	low molecular weight protein-tyrosine-phosphatase	-
AL510_RS03665 (AL510_03555)	ruvB	711380..712378 (-)	999	WP_002986679.1	Holliday junction branch migration DNA helicase RuvB	-
AL510_RS09845	comS	712425..712520 (-)	96	WP_198462994.1	quorum-sensing system DWW-type pheromone	Regulator
AL510_RS03670 (AL510_03560)	comR	712604..713515 (-)	912	WP_002986681.1	transcriptional regulator Rgg4/ComR	Regulator
AL510_RS03675 (AL510_03565)	purB	713647..714939 (-)	1293	WP_010921780.1	adenylosuccinate lyase	-
AL510_RS03680 (AL510_03570)	-	714957..716600 (-)	1644	WP_010921779.1	AIPR family protein	-
AL510_RS03685 (AL510_03575)	purK	716627..717700 (-)	1074	WP_015055885.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
AL510_RS03690 (AL510_03580)	purE	717687..718178 (-)	492	WP_015055884.1	5-(carboxyamino)imidazole ribonucleotide mutase	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 35757.27 Da
• Isoelectric Point: 4.4858

>NTDB_id=167507 AL510_RS03670 WP_002986681.1 712604..713515(-) (comR) [Streptococcus pyogenes strain FDAARGOS_149]
MLEHFGGKVKVLRLEKRISREDLCGDESELSVRQLARIELGQSIPSLSKVIFIAKALNVSVGYLTDGADLELPKRYKELK
YLILRTPTYMDDGKLQVREEQFDEIFEDYYDKLPEEEKIIIDCLQATLDTLLSENTNFGIDLLQEYFNQIKTKVRFRQND
LILLELYLAYLDIEGMDGQYSDKIFYDSLLDNLSEQFEQFELDELFIVNKIIIDISSLSLKNNRLDNLEKAIEMSQKIMA
KIQDWNRMPILKLIEWKYFLIKQKDIIKAEQSFMKACLFAQMTADQYLENKLIQEWEKDVKSY

Nucleotide

• Length: 912 bp

>NTDB_id=167507 AL510_RS03670 WP_002986681.1 712604..713515(-) (comR) [Streptococcus pyogenes strain FDAARGOS_149]
ATGTTAGAACATTTTGGTGGAAAAGTAAAAGTGTTAAGACTTGAAAAGAGGATTAGTCGCGAGGACTTGTGTGGGGATGA
GTCTGAACTTTCTGTTCGTCAATTAGCACGGATAGAACTAGGTCAATCCATACCAAGTTTAAGTAAGGTTATTTTTATTG
CAAAAGCCTTAAACGTTAGTGTCGGTTACTTAACTGATGGTGCTGATTTAGAACTACCTAAGCGTTACAAAGAATTAAAA
TACCTTATCTTAAGGACACCAACTTACATGGATGATGGAAAATTACAAGTACGAGAAGAGCAGTTTGATGAAATTTTTGA
GGATTATTATGATAAATTACCAGAGGAAGAGAAAATAATCATTGATTGTTTACAGGCAACTTTAGATACTTTATTGAGTG
AGAATACTAACTTTGGCATTGACTTACTTCAAGAATATTTTAATCAAATAAAGACTAAGGTACGCTTTAGGCAAAATGAT
TTAATACTTCTAGAATTATATTTAGCTTATCTTGATATTGAGGGAATGGATGGACAATATTCAGATAAGATTTTTTATGA
TTCTTTATTAGATAATCTATCAGAACAATTTGAACAATTTGAATTAGATGAATTATTTATAGTTAATAAGATTATCATTG
ATATTTCATCACTAAGCTTAAAAAATAACCGACTTGATAATTTAGAAAAAGCGATTGAAATGAGTCAAAAAATTATGGCG
AAAATTCAAGATTGGAATAGAATGCCTATTTTAAAACTAATAGAATGGAAATATTTTTTAATCAAACAAAAAGATATAAT
AAAAGCAGAACAATCATTTATGAAGGCATGTTTGTTCGCCCAAATGACAGCTGATCAGTATTTGGAAAACAAGTTAATTC
AAGAGTGGGAAAAAGATGTTAAAAGTTATTAA

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (12-64)

• ComR tetratricopeptide (ComR_TPR) (73-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS8232	100	100	1
comR	Streptococcus pyogenes MGAS315	58.472	99.34	0.581
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	51.37	96.37	0.495
comR	Streptococcus mutans UA159	46.358	99.67	0.462