Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   AL483_RS22860 Genome accession   NZ_CP014016
Coordinates   2056702..2058036 (-) Length   444 a.a.
NCBI ID   WP_061054989.1    Uniprot ID   A0AAE5HU10
Organism   Staphylococcus simulans strain FDAARGOS_124     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 2044593..2065369 2056702..2058036 within 0


Gene organization within MGE regions


Location: 2044593..2065369
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AL483_RS22785 (AL483_09990) - 2044650..2044898 (+) 249 Protein_1937 type I restriction enzyme endonuclease domain-containing protein -
  AL483_RS22790 (AL483_09995) - 2045088..2045597 (-) 510 WP_061054977.1 DUF1643 domain-containing protein -
  AL483_RS22795 (AL483_10000) - 2045615..2045926 (-) 312 WP_061054978.1 DUF960 family protein -
  AL483_RS22800 (AL483_10005) - 2046011..2046361 (-) 351 WP_061054979.1 SAUGI family uracil-DNA glycosylase inhibitor -
  AL483_RS25460 - 2046885..2047028 (+) 144 WP_158257850.1 hypothetical protein -
  AL483_RS22805 (AL483_12655) - 2047010..2047174 (+) 165 WP_226956313.1 hypothetical protein -
  AL483_RS22810 (AL483_10010) - 2047654..2048148 (-) 495 WP_061054980.1 GNAT family N-acetyltransferase -
  AL483_RS22815 (AL483_10015) - 2048404..2049780 (-) 1377 WP_061054981.1 amino acid permease -
  AL483_RS22825 (AL483_10025) - 2050559..2050780 (-) 222 WP_061054983.1 hypothetical protein -
  AL483_RS22830 (AL483_10030) - 2050794..2051291 (-) 498 WP_061054984.1 DUF1643 domain-containing protein -
  AL483_RS22835 (AL483_10035) - 2051307..2051618 (-) 312 WP_061054985.1 DUF960 family protein -
  AL483_RS22840 (AL483_10040) - 2051705..2052055 (-) 351 WP_061054986.1 SAUGI family uracil-DNA glycosylase inhibitor -
  AL483_RS22845 (AL483_10045) - 2052692..2054026 (+) 1335 WP_002479755.1 IS1182 family transposase -
  AL483_RS22850 (AL483_10050) - 2054216..2054950 (-) 735 WP_061054987.1 glucose 1-dehydrogenase -
  AL483_RS22855 (AL483_10055) ccrB 2055038..2056666 (-) 1629 WP_061054988.1 cassette chromosome recombinase CcrB Machinery gene
  AL483_RS22860 (AL483_10060) ccrA 2056702..2058036 (-) 1335 WP_061054989.1 cassette chromosome recombinase CcrA Machinery gene
  AL483_RS22865 (AL483_10065) cch1 2058224..2059993 (-) 1770 WP_061054990.1 cassette chromosome replicative helicase -
  AL483_RS22870 (AL483_10070) ssb 2059993..2060283 (-) 291 WP_061054991.1 cassette chromosome ssDNA-binding protein -
  AL483_RS25605 - 2060465..2061259 (+) 795 WP_237449266.1 hypothetical protein -
  AL483_RS25610 - 2061490..2061645 (+) 156 WP_237449267.1 hypothetical protein -
  AL483_RS25615 - 2061724..2062068 (+) 345 WP_237449268.1 hypothetical protein -
  AL483_RS22880 (AL483_10080) - 2062122..2062490 (+) 369 WP_237449269.1 hypothetical protein -
  AL483_RS22885 (AL483_10085) - 2062518..2063192 (-) 675 WP_001105999.1 IS6-like element IS257 family transposase -
  AL483_RS22890 (AL483_12660) - 2063382..2063905 (+) 524 Protein_1960 transposase -
  AL483_RS22900 (AL483_10095) - 2064272..2064946 (+) 675 WP_001105999.1 IS6-like element IS257 family transposase -
  AL483_RS22905 (AL483_10100) - 2065007..2065369 (-) 363 Protein_1962 recombinase family protein -

Sequence

Protein


Download         Length: 444 a.a.        Molecular weight: 51705.63 Da        Isoelectric Point: 10.0410

>NTDB_id=167253 AL483_RS22860 WP_061054989.1 2056702..2058036(-) (ccrA) [Staphylococcus simulans strain FDAARGOS_124]
MKQAIGYLRQSTTKQQSLAAQKQTIETLAKKYNIQHIIFYSDKQSGRTDNRTGYQQVIERIQQRQCEVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSIHDGYFDMDKAFDRLKLNIFISLAELESDNIGEQVKNGLKEKAKQGKLITTHAPFGYHYQ
NGTFIINNDESPTVKAVFNYYLQGYGYKKIAQYLETDDKCINRKPYQVRAIITNPNYCGRVINQYGQYDNMFPSIVSTSI
YEQAQAIRVNKQVKRTPSANLLKQKIKCPYCGSTLTNMAIRKTNHSLRYYVCPKNMNASRFICDFKGINAENLEKQVLES
CKKFFRDQQLYSKIKHAIEKQLKKQRMHDTSNTLTQKKLIENLAQGKIDVETFREQSQSINLQNKPIQAISDIRIKASLQ
KTIQKSFTLNMLYPYIDEIHITKNKELSGIYLKDEPLNIVNQAV

Nucleotide


Download         Length: 1335 bp        

>NTDB_id=167253 AL483_RS22860 WP_061054989.1 2056702..2058036(-) (ccrA) [Staphylococcus simulans strain FDAARGOS_124]
ATGAAACAAGCTATTGGTTATTTACGCCAAAGTACAACCAAGCAACAATCACTCGCCGCACAGAAACAAACTATCGAAAC
GCTCGCTAAAAAATACAATATCCAACACATCATCTTTTATAGCGATAAGCAATCAGGCAGAACGGATAATCGAACAGGTT
ATCAACAAGTCATCGAACGCATTCAACAAAGACAATGTGAAGTATTATGTTGTTATCGCTTGAATCGACTACATCGTAAT
TTGAAAAATGCATTAAAACTTATGAAACTGTGTCAAAAGTATCATGTTCATATTCTAAGTATTCATGATGGCTATTTTGA
TATGGATAAAGCGTTTGATCGCCTAAAACTTAATATATTCATAAGTCTCGCAGAATTAGAGTCCGATAATATTGGTGAAC
AAGTCAAGAATGGTCTTAAAGAAAAGGCAAAACAAGGTAAACTCATAACAACCCATGCGCCTTTCGGTTATCACTATCAA
AATGGTACTTTCATCATTAATAATGATGAATCACCTACCGTCAAAGCTGTATTCAATTATTATCTTCAAGGCTATGGTTA
TAAGAAAATCGCGCAATACCTAGAAACAGATGATAAATGTATTAATCGTAAACCCTACCAAGTACGCGCTATTATCACGA
ATCCTAATTATTGTGGTCGCGTTATCAATCAATATGGACAATATGACAACATGTTCCCATCTATTGTTTCGACCAGTATA
TACGAACAAGCTCAAGCAATACGAGTAAATAAACAAGTAAAGCGCACGCCTTCTGCTAATTTACTCAAACAAAAGATCAA
ATGTCCTTATTGTGGTTCAACCCTTACCAATATGGCCATTAGAAAAACCAATCATTCATTACGTTATTATGTCTGCCCTA
AAAACATGAATGCATCACGTTTTATATGTGACTTTAAAGGCATAAACGCTGAAAACCTAGAAAAACAGGTCTTAGAATCT
TGCAAAAAATTCTTTCGAGACCAACAGCTCTATTCGAAAATCAAACATGCTATTGAGAAACAGCTCAAAAAACAAAGGAT
GCATGATACTAGTAACACATTAACTCAGAAAAAGCTTATTGAAAATTTAGCACAAGGAAAAATTGATGTAGAAACATTCA
GAGAACAGTCCCAATCAATTAATCTACAGAATAAACCTATACAAGCAATAAGTGATATTCGGATAAAAGCATCACTACAA
AAGACTATACAGAAAAGTTTCACGTTAAACATGCTGTATCCCTATATTGATGAAATTCATATTACTAAAAATAAAGAATT
AAGCGGAATCTATTTAAAAGATGAGCCACTAAACATTGTTAATCAAGCGGTATAA

Domains

Predicted by InterproScan.

Recombinase (Recombinase)

(168-248)

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(261-321)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus COL

77.477

100

0.775
  ccrA Staphylococcus aureus N315

72.748

100

0.727

Multiple sequence alignment