Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ASL18_RS11420 Genome accession   NZ_CP013959
Coordinates   2217444..2218160 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain V605 isolate sequencing     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2212444..2223160
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ASL18_RS11390 (ASL18_11395) - 2212663..2213289 (+) 627 WP_000522384.1 nitroreductase family protein -
  ASL18_RS11395 (ASL18_11400) - 2213650..2214435 (+) 786 WP_000867960.1 carbon-nitrogen family hydrolase -
  ASL18_RS11400 (ASL18_11405) - 2215032..2215166 (-) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  ASL18_RS11405 (ASL18_11410) agrB 2215402..2215971 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  ASL18_RS11410 (ASL18_11415) agrD 2215968..2216108 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  ASL18_RS11415 (ASL18_11420) agrC 2216133..2217425 (+) 1293 WP_014532426.1 quorum-sensing sensor histidine kinase AgrC -
  ASL18_RS11420 (ASL18_11425) agrA 2217444..2218160 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  ASL18_RS11425 (ASL18_11430) - 2218232..2218339 (+) 108 WP_001790167.1 hypothetical protein -
  ASL18_RS11430 (ASL18_11435) - 2218527..2219486 (-) 960 WP_001253313.1 carbohydrate kinase -
  ASL18_RS11435 (ASL18_11440) - 2219483..2220967 (-) 1485 WP_000141417.1 sucrose-6-phosphate hydrolase -
  ASL18_RS11440 (ASL18_11445) - 2221116..2222066 (-) 951 WP_063660950.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=166720 ASL18_RS11420 WP_000688492.1 2217444..2218160(+) (agrA) [Staphylococcus aureus strain V605 isolate sequencing]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=166720 ASL18_RS11420 WP_000688492.1 2217444..2218160(+) (agrA) [Staphylococcus aureus strain V605 isolate sequencing]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment