Detailed information NTG0164860

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: BE845_RS02160
• Genome accession: NZ_CP016874
• Coordinates: 480319..480996 (+)
• Length: 225 a.a.
• NCBI ID: WP_011213604.1
• Uniprot ID: -
• Organism: Legionella pneumophila subsp. pneumophila strain FFI329
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 475319..485996

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BE845_RS02130 (BE845_02130)	-	475803..476012 (-)	210	WP_011215341.1	hypothetical protein	-
BE845_RS02135 (BE845_02135)	-	476300..477148 (+)	849	WP_011215340.1	23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ	-
BE845_RS02140 (BE845_02140)	gloB	477152..477916 (+)	765	WP_011215339.1	hydroxyacylglutathione hydrolase	-
BE845_RS02150 (BE845_02150)	-	478030..479469 (+)	1440	WP_011215338.1	LysM peptidoglycan-binding domain-containing protein	-
BE845_RS02155 (BE845_02155)	-	479713..480258 (+)	546	WP_011215337.1	septation protein A	-
BE845_RS02160 (BE845_02160)	ciaR	480319..480996 (+)	678	WP_011213604.1	response regulator	Regulator
BE845_RS02165 (BE845_02165)	-	480993..482408 (+)	1416	WP_011215336.1	ATP-binding protein	-
BE845_RS02170 (BE845_02170)	-	482449..482769 (-)	321	WP_011215335.1	hypothetical protein	-
BE845_RS02175 (BE845_02175)	ruvA	482820..483419 (-)	600	WP_011213600.1	Holliday junction branch migration protein RuvA	-
BE845_RS02180 (BE845_02180)	ruvC	483416..483940 (-)	525	WP_011215334.1	crossover junction endodeoxyribonuclease RuvC	-
BE845_RS02185 (BE845_02185)	-	483940..484683 (-)	744	WP_011215333.1	YebC/PmpR family DNA-binding transcriptional regulator	-

Sequence

Protein

• Length: 225 a.a.
• Molecular weight: 25151.74 Da
• Isoelectric Point: 4.9981

>NTDB_id=164860 BE845_RS02160 WP_011213604.1 480319..480996(+) (ciaR) [Legionella pneumophila subsp. pneumophila strain FFI329]
MRLLLVEDDELLGDAVKAGLTQFGYVVDWLKDGEAARAALKSESFELIILDLGLPKLSGLSLLQNIRHDGNSTPVIILTA
RESIEDRVKGLDSGADDYLIKPFDLNELSARIRALVRRSQGRADSVLQYKNITLDPAAHSVFVDDVLVNVPRREFALLQK
LLENSGQVLSREQLMQSIYGWEEDVDSNALEVHIHNLRKKLNANFIRTIRGVGYMAEKNDSVLLS

Nucleotide

• Length: 678 bp

>NTDB_id=164860 BE845_RS02160 WP_011213604.1 480319..480996(+) (ciaR) [Legionella pneumophila subsp. pneumophila strain FFI329]
ATGAGATTATTACTTGTTGAAGACGATGAACTGCTTGGCGATGCAGTAAAAGCCGGACTGACACAATTTGGTTATGTTGT
TGACTGGCTAAAAGATGGCGAAGCTGCTCGGGCGGCTCTCAAATCAGAGTCTTTTGAATTAATTATTCTTGACTTGGGAT
TACCTAAATTATCCGGTTTATCATTATTGCAAAACATCAGACATGATGGAAATAGCACACCTGTGATTATTCTTACAGCT
CGAGAATCAATAGAAGATCGGGTGAAAGGCTTAGATAGCGGTGCTGACGATTATCTTATTAAACCTTTTGATTTAAACGA
ATTAAGTGCAAGGATTAGAGCATTGGTAAGACGCTCTCAGGGCAGAGCTGATTCCGTGTTGCAATATAAAAATATTACCC
TCGATCCTGCGGCTCATTCTGTATTCGTGGATGATGTACTCGTCAATGTTCCAAGAAGAGAATTTGCTCTATTGCAGAAA
TTACTTGAAAACAGTGGCCAGGTTTTATCTCGAGAACAATTAATGCAGAGTATTTATGGCTGGGAAGAAGACGTGGACAG
TAATGCTCTCGAAGTTCATATCCATAATTTACGTAAAAAACTTAACGCAAACTTTATCCGCACTATACGTGGTGTAGGAT
ATATGGCTGAAAAAAATGACAGTGTACTTCTATCGTGA

Domains

Predicted by InterProScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (148-215)

• Response regulator receiver domain (Response_reg) (4-113)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus pneumoniae Rx1	38.356	97.333	0.373
ciaR	Streptococcus pneumoniae D39	38.356	97.333	0.373
ciaR	Streptococcus pneumoniae R6	38.356	97.333	0.373
ciaR	Streptococcus pneumoniae TIGR4	38.356	97.333	0.373
ciaR	Streptococcus mutans UA159	37.9	97.333	0.369
micA	Streptococcus pneumoniae Cp1015	35.345	100	0.364