Detailed information NTG0164850

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: BE844_RS14980
• Genome accession: NZ_CP016873
• Coordinates: 3337391..3338068 (-)
• Length: 225 a.a.
• NCBI ID: WP_011213604.1
• Uniprot ID: -
• Organism: Legionella pneumophila subsp. pneumophila strain FFI105
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 3332391..3343068

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BE844_RS14955 (BE844_14955)	-	3333704..3334447 (+)	744	WP_070322064.1	YebC/PmpR family DNA-binding transcriptional regulator	-
BE844_RS14960 (BE844_14960)	ruvC	3334447..3334971 (+)	525	WP_011215334.1	crossover junction endodeoxyribonuclease RuvC	-
BE844_RS14965 (BE844_14965)	ruvA	3334968..3335567 (+)	600	WP_011213600.1	Holliday junction branch migration protein RuvA	-
BE844_RS14970 (BE844_14970)	-	3335618..3335938 (+)	321	WP_070322063.1	hypothetical protein	-
BE844_RS14975 (BE844_14975)	-	3335979..3337394 (-)	1416	WP_070322062.1	ATP-binding protein	-
BE844_RS14980 (BE844_14980)	ciaR	3337391..3338068 (-)	678	WP_011213604.1	response regulator	Regulator
BE844_RS14985 (BE844_14985)	-	3338129..3338674 (-)	546	WP_011215337.1	septation protein A	-
BE844_RS14990 (BE844_14990)	-	3338918..3340357 (-)	1440	WP_011215338.1	LysM peptidoglycan-binding domain-containing protein	-
BE844_RS15000 (BE844_15000)	gloB	3340471..3341235 (-)	765	WP_070322061.1	hydroxyacylglutathione hydrolase	-
BE844_RS15005 (BE844_15005)	-	3341239..3342087 (-)	849	WP_011215340.1	23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ	-
BE844_RS15010 (BE844_15010)	-	3342375..3342584 (+)	210	WP_011215341.1	hypothetical protein	-

Sequence

Protein

• Length: 225 a.a.
• Molecular weight: 25151.74 Da
• Isoelectric Point: 4.9981

>NTDB_id=164850 BE844_RS14980 WP_011213604.1 3337391..3338068(-) (ciaR) [Legionella pneumophila subsp. pneumophila strain FFI105]
MRLLLVEDDELLGDAVKAGLTQFGYVVDWLKDGEAARAALKSESFELIILDLGLPKLSGLSLLQNIRHDGNSTPVIILTA
RESIEDRVKGLDSGADDYLIKPFDLNELSARIRALVRRSQGRADSVLQYKNITLDPAAHSVFVDDVLVNVPRREFALLQK
LLENSGQVLSREQLMQSIYGWEEDVDSNALEVHIHNLRKKLNANFIRTIRGVGYMAEKNDSVLLS

Nucleotide

• Length: 678 bp

>NTDB_id=164850 BE844_RS14980 WP_011213604.1 3337391..3338068(-) (ciaR) [Legionella pneumophila subsp. pneumophila strain FFI105]
ATGAGATTATTACTTGTTGAAGACGATGAACTGCTTGGCGATGCAGTAAAAGCCGGACTGACACAATTTGGTTATGTTGT
TGACTGGCTAAAAGATGGCGAAGCTGCTCGGGCGGCTCTCAAATCAGAGTCTTTTGAATTAATTATTCTTGACTTGGGAT
TACCTAAATTATCCGGTTTATCATTATTGCAAAACATCAGACATGATGGAAATAGCACACCTGTGATTATTCTTACAGCT
CGAGAATCAATAGAAGATCGGGTGAAAGGCTTAGATAGCGGTGCTGACGATTATCTTATTAAACCTTTTGATTTAAACGA
ATTAAGTGCAAGGATTAGAGCATTGGTAAGACGCTCTCAGGGCAGAGCTGATTCCGTGTTGCAATATAAAAATATTACCC
TCGATCCTGCGGCTCATTCTGTATTCGTGGATGATGTACTCGTCAATGTTCCAAGAAGAGAATTTGCTCTATTGCAGAAA
TTACTTGAAAACAGTGGCCAGGTTTTATCTCGAGAACAATTAATGCAGAGTATTTATGGCTGGGAAGAAGACGTGGACAG
TAATGCTCTCGAAGTTCATATCCATAATTTACGTAAAAAACTTAACGCAAACTTTATCCGCACTATACGTGGTGTAGGAT
ATATGGCTGAAAAAAATGACAGTGTACTTCTATCGTGA

Domains

Predicted by InterProScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (148-215)

• Response regulator receiver domain (Response_reg) (4-113)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus pneumoniae Rx1	38.356	97.333	0.373
ciaR	Streptococcus pneumoniae D39	38.356	97.333	0.373
ciaR	Streptococcus pneumoniae R6	38.356	97.333	0.373
ciaR	Streptococcus pneumoniae TIGR4	38.356	97.333	0.373
ciaR	Streptococcus mutans UA159	37.9	97.333	0.369
micA	Streptococcus pneumoniae Cp1015	35.345	100	0.364