Detailed information NTG0164667

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: BE842_RS02175
• Genome accession: NZ_CP016870
• Coordinates: 467682..468359 (-)
• Length: 225 a.a.
• NCBI ID: WP_011213604.1
• Uniprot ID: -
• Organism: Legionella pneumophila subsp. pneumophila strain FFI103
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 462682..473359

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BE842_RS02150 (BE842_02150)	-	463996..464739 (+)	744	WP_011215333.1	YebC/PmpR family DNA-binding transcriptional regulator	-
BE842_RS02155 (BE842_02155)	ruvC	464739..465262 (+)	524	Protein_428	crossover junction endodeoxyribonuclease RuvC	-
BE842_RS02160 (BE842_02160)	ruvA	465259..465858 (+)	600	WP_011213600.1	Holliday junction branch migration protein RuvA	-
BE842_RS02165 (BE842_02165)	-	465909..466229 (+)	321	WP_011215335.1	hypothetical protein	-
BE842_RS02170 (BE842_02170)	-	466270..467685 (-)	1416	WP_011215336.1	ATP-binding protein	-
BE842_RS02175 (BE842_02175)	ciaR	467682..468359 (-)	678	WP_011213604.1	response regulator	Regulator
BE842_RS02180 (BE842_02180)	-	468420..468965 (-)	546	WP_011215337.1	septation protein A	-
BE842_RS02185 (BE842_02185)	-	469209..470648 (-)	1440	WP_011215338.1	LysM peptidoglycan-binding domain-containing protein	-
BE842_RS02195 (BE842_02195)	gloB	470762..471526 (-)	765	WP_011215339.1	hydroxyacylglutathione hydrolase	-
BE842_RS02200 (BE842_02200)	-	471530..472378 (-)	849	WP_011215340.1	23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ	-
BE842_RS02205 (BE842_02205)	-	472666..472875 (+)	210	WP_011215341.1	hypothetical protein	-

Sequence

Protein

• Length: 225 a.a.
• Molecular weight: 25151.74 Da
• Isoelectric Point: 4.9981

>NTDB_id=164667 BE842_RS02175 WP_011213604.1 467682..468359(-) (ciaR) [Legionella pneumophila subsp. pneumophila strain FFI103]
MRLLLVEDDELLGDAVKAGLTQFGYVVDWLKDGEAARAALKSESFELIILDLGLPKLSGLSLLQNIRHDGNSTPVIILTA
RESIEDRVKGLDSGADDYLIKPFDLNELSARIRALVRRSQGRADSVLQYKNITLDPAAHSVFVDDVLVNVPRREFALLQK
LLENSGQVLSREQLMQSIYGWEEDVDSNALEVHIHNLRKKLNANFIRTIRGVGYMAEKNDSVLLS

Nucleotide

• Length: 678 bp

>NTDB_id=164667 BE842_RS02175 WP_011213604.1 467682..468359(-) (ciaR) [Legionella pneumophila subsp. pneumophila strain FFI103]
ATGAGATTATTACTTGTTGAAGACGATGAACTGCTTGGCGATGCAGTAAAAGCCGGACTGACACAATTTGGTTATGTTGT
TGACTGGCTAAAAGATGGCGAAGCTGCTCGGGCGGCTCTCAAATCAGAGTCTTTTGAATTAATTATTCTTGACTTGGGAT
TACCTAAATTATCCGGTTTATCATTATTGCAAAACATCAGACATGATGGAAATAGCACACCTGTGATTATTCTTACAGCT
CGAGAATCAATAGAAGATCGGGTGAAAGGCTTAGATAGCGGTGCTGACGATTATCTTATTAAACCTTTTGATTTAAACGA
ATTAAGTGCAAGGATTAGAGCATTGGTAAGACGCTCTCAGGGCAGAGCTGATTCCGTGTTGCAATATAAAAATATTACCC
TCGATCCTGCGGCTCATTCTGTATTCGTGGATGATGTACTCGTCAATGTTCCAAGAAGAGAATTTGCTCTATTGCAGAAA
TTACTTGAAAACAGTGGCCAGGTTTTATCTCGAGAACAATTAATGCAGAGTATTTATGGCTGGGAAGAAGACGTGGACAG
TAATGCTCTCGAAGTTCATATCCATAATTTACGTAAAAAACTTAACGCAAACTTTATCCGCACTATACGTGGTGTAGGAT
ATATGGCTGAAAAAAATGACAGTGTACTTCTATCGTGA

Domains

Predicted by InterProScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (148-215)

• Response regulator receiver domain (Response_reg) (4-113)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus pneumoniae Rx1	38.356	97.333	0.373
ciaR	Streptococcus pneumoniae D39	38.356	97.333	0.373
ciaR	Streptococcus pneumoniae R6	38.356	97.333	0.373
ciaR	Streptococcus pneumoniae TIGR4	38.356	97.333	0.373
ciaR	Streptococcus mutans UA159	37.9	97.333	0.369
micA	Streptococcus pneumoniae Cp1015	35.345	100	0.364