Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   AU077_RS01530 Genome accession   NZ_CP013688
Coordinates   299335..300027 (+) Length   230 a.a.
NCBI ID   WP_014295163.1    Uniprot ID   A0A2G3NPQ1
Organism   Streptococcus gallolyticus strain ICDDRB-NRC-S1     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 294335..305027
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AU077_RS01505 (AU077_01505) - 294379..295752 (-) 1374 WP_058621433.1 TrkH family potassium uptake protein -
  AU077_RS01510 (AU077_01510) rsmG 295819..296532 (-) 714 WP_039671169.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  AU077_RS01515 (AU077_01515) - 296861..297412 (+) 552 WP_014295166.1 LemA family protein -
  AU077_RS01520 (AU077_01520) htpX 297539..298441 (+) 903 WP_014295165.1 zinc metalloprotease HtpX -
  AU077_RS01525 (AU077_01525) - 298566..299102 (+) 537 WP_014295164.1 DUF177 domain-containing protein -
  AU077_RS01530 (AU077_01530) covR 299335..300027 (+) 693 WP_014295163.1 response regulator transcription factor Regulator
  AU077_RS01535 (AU077_01535) - 300120..301511 (+) 1392 WP_230937579.1 HAMP domain-containing sensor histidine kinase -
  AU077_RS01540 (AU077_01540) nrdR 301700..302197 (+) 498 WP_039671167.1 transcriptional regulator NrdR -
  AU077_RS01545 (AU077_01545) - 302181..303341 (+) 1161 WP_058621434.1 DnaD domain protein -
  AU077_RS01550 (AU077_01550) dnaI 303352..304254 (+) 903 WP_014295159.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26458.35 Da        Isoelectric Point: 4.8614

>NTDB_id=164036 AU077_RS01530 WP_014295163.1 299335..300027(+) (covR) [Streptococcus gallolyticus strain ICDDRB-NRC-S1]
MSKKILIIEDEKNLARFVSLELQHEGYSVVVENNGRLGLQTALDDDFDLILLDLMLPDMDGFEITRRLRLGKETSIIMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARVRAVFRRQDVESKREQDSRGKEGLLGLRLNPQNRSAVRGDDEISLTKR
EYDLLSVLLSNVNRVMTREELLSSVWRYDTDIETNVVDVYIRYLRGKVDIPGKESYIQTVRGMGYIIREK

Nucleotide


Download         Length: 693 bp        

>NTDB_id=164036 AU077_RS01530 WP_014295163.1 299335..300027(+) (covR) [Streptococcus gallolyticus strain ICDDRB-NRC-S1]
ATGAGTAAAAAGATTTTAATTATTGAAGATGAAAAAAATCTTGCACGTTTTGTATCTTTAGAGTTGCAACATGAAGGTTA
TTCAGTAGTAGTAGAAAATAATGGACGACTTGGCCTACAAACAGCTCTAGATGATGATTTTGATTTAATTTTGTTAGACT
TGATGCTTCCAGATATGGATGGTTTTGAAATTACACGCCGTCTTCGATTAGGAAAAGAGACTTCTATTATTATGATGACA
GCTCGTGATTCAATTATGGATGTTGTTGCTGGGCTTGATCGTGGTGCAGATGACTATATTGTTAAACCATTTGCAATTGA
AGAATTGTTAGCTCGTGTCCGTGCTGTTTTTCGTCGTCAAGATGTTGAATCTAAGCGTGAACAAGATAGTCGAGGAAAAG
AAGGGCTACTTGGACTACGCTTAAACCCTCAAAATCGTTCTGCTGTTCGAGGTGATGATGAAATTTCACTTACAAAACGT
GAATATGATTTGCTAAGTGTTCTTTTATCAAATGTTAATCGTGTAATGACACGTGAAGAATTATTGTCTAGTGTTTGGAG
ATATGATACAGATATTGAGACAAATGTTGTTGATGTTTATATCCGTTACCTTCGCGGAAAAGTCGATATTCCAGGTAAAG
AATCTTACATTCAAACAGTTCGTGGAATGGGATACATTATTCGAGAAAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2G3NPQ1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

74.348

100

0.743
  covR Lactococcus lactis subsp. lactis strain DGCC12653

63.755

99.565

0.635
  vicR Streptococcus mutans UA159

42.857

100

0.43
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.422

Multiple sequence alignment