Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   APQ13_RS08905 Genome accession   NZ_CP013237
Coordinates   1839351..1840043 (+) Length   230 a.a.
NCBI ID   WP_002262121.1    Uniprot ID   -
Organism   Streptococcus mutans strain NG8 isolate Dental Plaque     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1834351..1845043
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  APQ13_RS08885 (APQ13_08865) - 1834462..1837074 (-) 2613 WP_002289694.1 ABC transporter permease -
  APQ13_RS08890 (APQ13_08870) - 1837076..1837783 (-) 708 WP_002265123.1 ABC transporter ATP-binding protein -
  APQ13_RS08895 (APQ13_08875) - 1837891..1838466 (+) 576 WP_002265122.1 TetR/AcrR family transcriptional regulator -
  APQ13_RS08900 (APQ13_08880) - 1838459..1838995 (+) 537 WP_002262122.1 DUF177 domain-containing protein -
  APQ13_RS08905 (APQ13_08885) covR 1839351..1840043 (+) 693 WP_002262121.1 response regulator GcrR Regulator
  APQ13_RS08910 (APQ13_08890) nrdR 1840412..1840903 (+) 492 WP_002262120.1 transcriptional regulator NrdR -
  APQ13_RS08915 (APQ13_08895) - 1840890..1842059 (+) 1170 WP_002262119.1 DnaD domain protein -
  APQ13_RS08920 (APQ13_08900) dnaI 1842060..1842959 (+) 900 WP_002267936.1 primosomal protein DnaI -
  APQ13_RS08925 (APQ13_08905) der 1842972..1844282 (+) 1311 WP_002266899.1 ribosome biogenesis GTPase Der -
  APQ13_RS08930 (APQ13_08910) - 1844357..1844983 (+) 627 WP_002266898.1 hypothetical protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26739.72 Da        Isoelectric Point: 4.9899

>NTDB_id=161017 APQ13_RS08905 WP_002262121.1 1839351..1840043(+) (covR) [Streptococcus mutans strain NG8 isolate Dental Plaque]
MAKDILIIEDEKKLAKFVSLELQHEGYEVEVTYDGRSGLERALEKDFDLILLDLMLPEMDGYEVIRRLQLEKTTYVIIIT
ARDSIMDIVTGLDRGADGYIVKPFAIEELLARVRAIFRRQDIEKAKHSSKNDTTYRDLKLDVHNRAAIRNGETIPLTKRE
FDLLNALVENINQVMTREELLARVWKYDQEAETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYIIRENN

Nucleotide


Download         Length: 693 bp        

>NTDB_id=161017 APQ13_RS08905 WP_002262121.1 1839351..1840043(+) (covR) [Streptococcus mutans strain NG8 isolate Dental Plaque]
ATGGCTAAGGACATTTTAATTATTGAAGATGAAAAAAAACTTGCAAAGTTTGTTTCTTTAGAATTACAACATGAAGGATA
TGAGGTTGAAGTGACATATGATGGGCGTTCTGGCCTAGAAAGAGCACTTGAAAAAGATTTCGATCTCATCCTTCTTGATT
TAATGTTACCAGAGATGGACGGGTATGAAGTGATTCGTCGTTTACAATTGGAAAAGACAACTTATGTTATTATTATCACT
GCTCGTGACTCCATTATGGATATTGTGACTGGTCTTGATCGTGGAGCAGATGGTTATATCGTTAAACCATTTGCTATTGA
AGAATTACTAGCTCGTGTTCGTGCCATATTTCGTCGTCAAGATATTGAGAAAGCTAAGCATTCTTCTAAAAATGACACTA
CCTATCGTGATTTGAAATTAGATGTTCATAACCGAGCTGCCATTAGAAATGGTGAGACAATTCCTTTAACTAAACGTGAA
TTTGATTTATTAAATGCTCTTGTAGAAAATATCAATCAAGTTATGACTAGAGAAGAGCTTTTGGCCCGTGTTTGGAAGTA
TGATCAAGAAGCTGAGACTAATGTTGTCGATGTTTATATTCGCTATCTTCGTGGGAAGATTGATGTTCCTGGTAAAGAAA
GCTATATTCAGACTGTCCGCGGCATGGGGTATATCATTCGCGAAAATAATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

78.07

99.13

0.774
  covR Lactococcus lactis subsp. lactis strain DGCC12653

63.436

98.696

0.626
  vicR Streptococcus mutans UA159

42.857

100

0.43
  micA Streptococcus pneumoniae Cp1015

41.631

100

0.422

Multiple sequence alignment