Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   HSISS4_RS05665 Genome accession   NZ_CP013216
Coordinates   1186117..1187532 (-) Length   471 a.a.
NCBI ID   WP_037620265.1    Uniprot ID   -
Organism   Streptococcus salivarius strain HSISS4     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1181117..1192532
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HSISS4_RS05635 (HSISS4_01090) - 1181755..1182153 (-) 399 WP_021144038.1 cytidine deaminase -
  HSISS4_RS05640 (HSISS4_01091) deoC 1182140..1182802 (-) 663 WP_021144037.1 deoxyribose-phosphate aldolase -
  HSISS4_RS05645 (HSISS4_01092) - 1182836..1184113 (-) 1278 WP_059749185.1 pyrimidine-nucleoside phosphorylase -
  HSISS4_RS05650 (HSISS4_01093) - 1184110..1184700 (-) 591 WP_014633038.1 class I SAM-dependent methyltransferase -
  HSISS4_RS05655 (HSISS4_01094) coaA 1184813..1185733 (+) 921 WP_059749264.1 type I pantothenate kinase -
  HSISS4_RS05660 (HSISS4_01095) rpsT 1185803..1186039 (+) 237 WP_004182129.1 30S ribosomal protein S20 -
  HSISS4_RS05665 (HSISS4_01096) ciaH 1186117..1187532 (-) 1416 WP_037620265.1 sensor histidine kinase Regulator
  HSISS4_RS05670 (HSISS4_01097) ciaR 1187522..1188196 (-) 675 WP_021144033.1 response regulator transcription factor Regulator
  HSISS4_RS05675 (HSISS4_01098) - 1188394..1190064 (-) 1671 WP_021144032.1 formate--tetrahydrofolate ligase -
  HSISS4_RS05680 (HSISS4_01099) - 1190258..1190941 (+) 684 WP_059749187.1 phosphopantothenate--cysteine ligase -
  HSISS4_RS05685 (HSISS4_01100) coaC 1190934..1191479 (+) 546 WP_021144029.1 phosphopantothenoylcysteine decarboxylase -
  HSISS4_RS05690 (HSISS4_01101) - 1191508..1192080 (+) 573 WP_021144028.1 ECF transporter S component -

Sequence

Protein


Download         Length: 471 a.a.        Molecular weight: 53481.16 Da        Isoelectric Point: 7.4509

>NTDB_id=160710 HSISS4_RS05665 WP_037620265.1 1186117..1187532(-) (ciaH) [Streptococcus salivarius strain HSISS4]
MLTKFFNYLFRRIKSDGFKSFIHFFATFSGIFLIMTVMILQILSYGVYSNVDSSLKMAATKTNSYLEMEMLKRELFLTSE
VDQNNTTTIYQAYDTNESTAETSDSSDSKKEPKKKSKIEDAPHDLSVAANTSVLVLDKSGKVLNVVDKFSSLSNLPIDKN
NIDVISKGSAQNYFDQTEKYRLITEKVDNSLYPDAKYLVIAINTTQLEEATERYVKLIVIMMSFFWLLSVAASMYLAKWS
RRPIQESLEKQKAFVENASHELRTPLAVIQNRLEVLFRKPESTILDNSENIASSLDEVRNMRLLTTNLLNLARRDDGIKP
EIETLEPAFFDTVFTNYAMIAEENEKGFTAQNQVGRPIQTDKTLLKQLMTILFDNAIKYTEDDGHVTFTVRTNDRHLYIS
VADNGPGISDSDKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIVLALKGTIVVKDNQPKGTIFEVKITGV

Nucleotide


Download         Length: 1416 bp        

>NTDB_id=160710 HSISS4_RS05665 WP_037620265.1 1186117..1187532(-) (ciaH) [Streptococcus salivarius strain HSISS4]
ATGCTGACTAAATTTTTCAATTATCTCTTTAGGAGAATCAAGTCAGACGGATTTAAGTCGTTCATTCATTTCTTTGCCAC
TTTTTCTGGTATTTTCCTTATCATGACTGTCATGATTTTACAGATTCTGAGTTACGGCGTTTATTCCAATGTGGACTCTA
GTCTGAAAATGGCAGCCACTAAAACCAATTCTTATTTAGAAATGGAAATGCTAAAACGGGAACTTTTTCTGACTTCTGAG
GTAGATCAAAATAATACGACAACCATTTACCAAGCCTATGATACTAATGAGTCGACAGCTGAAACATCTGACTCGAGTGA
CTCTAAGAAAGAGCCTAAGAAGAAATCAAAGATAGAAGATGCTCCTCACGATTTATCAGTTGCGGCAAATACCAGTGTCT
TGGTACTTGATAAGAGTGGAAAAGTCCTCAATGTCGTTGATAAATTTTCAAGCTTATCCAATTTACCAATAGACAAAAAT
AACATTGATGTTATCAGCAAGGGAAGTGCTCAGAATTATTTCGATCAAACGGAAAAGTACCGTCTGATTACTGAAAAAGT
AGATAATAGCCTCTATCCTGATGCTAAGTACCTTGTTATTGCGATTAATACAACTCAATTGGAAGAAGCCACTGAACGTT
ATGTTAAGCTAATTGTCATCATGATGAGTTTCTTCTGGCTTTTATCTGTTGCGGCTAGTATGTATTTGGCTAAGTGGTCA
AGACGTCCTATCCAGGAAAGCTTGGAGAAGCAGAAGGCTTTTGTTGAGAATGCTAGCCATGAGTTACGGACACCGCTTGC
TGTGATTCAAAACAGATTAGAAGTTCTTTTCCGCAAGCCTGAGAGCACCATTCTAGATAATTCAGAGAATATTGCTTCAA
GCCTTGATGAAGTACGCAACATGCGTCTTTTGACGACTAATCTTTTGAACTTGGCTCGTCGTGACGATGGTATTAAACCA
GAAATCGAAACCTTAGAACCTGCTTTCTTTGATACAGTCTTTACCAACTATGCCATGATTGCAGAAGAAAATGAGAAAGG
TTTCACGGCTCAAAACCAAGTTGGTCGTCCAATCCAGACTGATAAAACGTTATTGAAACAGTTAATGACCATCTTATTTG
ATAATGCTATTAAATATACGGAAGATGATGGACATGTTACCTTTACTGTTCGCACTAATGACCGCCATCTTTATATTTCT
GTAGCTGATAATGGTCCTGGAATATCAGATAGTGATAAGAAAAAAATCTTTGATCGCTTTTATCGCGTAGATAAGGCTAG
AACCAGACAAAAAGGTGGGTTTGGACTTGGCTTATCCCTAGCGCAACAAATTGTTTTAGCCCTAAAAGGAACAATTGTTG
TTAAAGATAATCAACCAAAGGGAACGATTTTTGAAGTTAAGATTACTGGAGTTTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(252-317)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(361-468)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.739

97.665

0.554
  ciaH Streptococcus pneumoniae Rx1

50.431

98.514

0.497
  ciaH Streptococcus pneumoniae D39

50.431

98.514

0.497
  ciaH Streptococcus pneumoniae R6

50.431

98.514

0.497
  ciaH Streptococcus pneumoniae TIGR4

50.431

98.514

0.497

Multiple sequence alignment