Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   A9P84_RS06310 Genome accession   NZ_CP016030
Coordinates   1383928..1384605 (-) Length   225 a.a.
NCBI ID   WP_011213604.1    Uniprot ID   -
Organism   Legionella pneumophila strain OLDA     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1378928..1389605
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A9P84_RS06285 (A9P84_06280) ruvC 1379099..1379623 (+) 525 WP_011213599.1 crossover junction endodeoxyribonuclease RuvC -
  A9P84_RS06290 (A9P84_06285) ruvA 1379620..1380219 (+) 600 WP_011213600.1 Holliday junction branch migration protein RuvA -
  A9P84_RS06295 (A9P84_06290) - 1380269..1380589 (+) 321 WP_011213601.1 hypothetical protein -
  A9P84_RS06300 (A9P84_06295) lem8 1380630..1382234 (-) 1605 WP_011213602.1 Dot/Icm T4SS effector Lem8 -
  A9P84_RS06305 (A9P84_06300) - 1382516..1383931 (-) 1416 WP_011213603.1 ATP-binding protein -
  A9P84_RS06310 (A9P84_06305) ciaR 1383928..1384605 (-) 678 WP_011213604.1 response regulator Regulator
  A9P84_RS06315 (A9P84_06310) - 1384666..1385211 (-) 546 WP_011213605.1 septation protein A -
  A9P84_RS06320 (A9P84_06315) - 1385454..1386893 (-) 1440 WP_011213606.1 lytic transglycosylase -
  A9P84_RS06330 (A9P84_06325) gloB 1387007..1387771 (-) 765 WP_011213607.1 hydroxyacylglutathione hydrolase -
  A9P84_RS06335 (A9P84_06330) - 1387775..1388623 (-) 849 WP_011213608.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
  A9P84_RS06340 (A9P84_06335) - 1388909..1389118 (+) 210 WP_011213609.1 hypothetical protein -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25151.74 Da        Isoelectric Point: 4.9981

>NTDB_id=159037 A9P84_RS06310 WP_011213604.1 1383928..1384605(-) (ciaR) [Legionella pneumophila strain OLDA]
MRLLLVEDDELLGDAVKAGLTQFGYVVDWLKDGEAARAALKSESFELIILDLGLPKLSGLSLLQNIRHDGNSTPVIILTA
RESIEDRVKGLDSGADDYLIKPFDLNELSARIRALVRRSQGRADSVLQYKNITLDPAAHSVFVDDVLVNVPRREFALLQK
LLENSGQVLSREQLMQSIYGWEEDVDSNALEVHIHNLRKKLNANFIRTIRGVGYMAEKNDSVLLS

Nucleotide


Download         Length: 678 bp        

>NTDB_id=159037 A9P84_RS06310 WP_011213604.1 1383928..1384605(-) (ciaR) [Legionella pneumophila strain OLDA]
ATGAGATTATTACTTGTTGAAGACGATGAACTGCTTGGCGATGCAGTAAAAGCCGGACTGACACAATTTGGTTACGTTGT
TGACTGGCTAAAAGATGGCGAAGCTGCTCGGGCGGCTCTCAAATCAGAGTCTTTTGAATTAATTATTCTTGACTTGGGAT
TACCTAAATTATCCGGTTTATCATTATTGCAAAACATCAGACATGATGGAAATAGCACACCTGTGATTATTCTTACAGCT
CGAGAATCAATAGAAGATCGGGTAAAAGGCTTAGATAGCGGTGCTGACGATTATCTTATTAAACCTTTTGATTTAAACGA
ATTAAGTGCAAGGATTAGAGCATTAGTAAGGCGCTCTCAGGGCAGAGCTGATTCCGTGCTGCAATATAAAAATATTACTC
TCGATCCTGCTGCTCATTCTGTATTCGTGGATGATGTACTCGTCAATGTTCCAAGAAGAGAATTTGCTCTATTACAGAAA
TTACTTGAAAACAGTGGCCAGGTTTTATCTCGAGAACAATTAATGCAGAGTATTTATGGCTGGGAAGAAGACGTGGACAG
TAATGCTCTAGAAGTTCACATCCATAATTTACGTAAAAAACTTAACGCAAACTTTATCCGCACTATACGTGGTGTAGGAT
ATATGGCTGAAAAAAATGACAGTGTACTTCTATCGTGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(148-215)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.356

97.333

0.373
  ciaR Streptococcus pneumoniae D39

38.356

97.333

0.373
  ciaR Streptococcus pneumoniae R6

38.356

97.333

0.373
  ciaR Streptococcus pneumoniae TIGR4

38.356

97.333

0.373
  ciaR Streptococcus mutans UA159

37.9

97.333

0.369
  micA Streptococcus pneumoniae Cp1015

35.345

100

0.364

Multiple sequence alignment