Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   ACT74_RS07010 Genome accession   NZ_CP012958
Coordinates   1493456..1494679 (+) Length   407 a.a.
NCBI ID   WP_005567968.1    Uniprot ID   -
Organism   Aggregatibacter actinomycetemcomitans strain VT1169     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1488456..1499679
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACT74_RS06990 (ACT74_06985) nanQ 1489957..1490427 (+) 471 WP_005547536.1 N-acetylneuraminate anomerase -
  ACT74_RS06995 (ACT74_06990) ampD 1490901..1491455 (-) 555 WP_005567973.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  ACT74_RS07000 (ACT74_06995) pilA 1491577..1492029 (+) 453 WP_005586498.1 pilin Machinery gene
  ACT74_RS07005 (ACT74_07000) - 1492056..1493463 (+) 1408 Protein_1378 GspE/PulE family protein -
  ACT74_RS07010 (ACT74_07005) pilC 1493456..1494679 (+) 1224 WP_005567968.1 type II secretion system F family protein Machinery gene
  ACT74_RS07015 (ACT74_07010) - 1494676..1495365 (+) 690 WP_005547547.1 prepilin peptidase -
  ACT74_RS07020 (ACT74_07015) coaE 1495415..1496038 (+) 624 WP_005547548.1 dephospho-CoA kinase -
  ACT74_RS07025 (ACT74_07020) yacG 1496028..1496240 (+) 213 WP_005567966.1 DNA gyrase inhibitor YacG -
  ACT74_RS07030 (ACT74_07025) - 1496240..1496512 (+) 273 WP_005547552.1 GNAT family N-acetyltransferase -
  ACT74_RS07035 (ACT74_07030) - 1496909..1498282 (+) 1374 WP_005547554.1 alanine/glycine:cation symporter family protein -
  ACT74_RS07040 (ACT74_07035) raiA 1498510..1498833 (+) 324 WP_005540708.1 ribosome-associated translation inhibitor RaiA -
  ACT74_RS07045 (ACT74_07040) - 1498982..1499536 (+) 555 WP_005540709.1 DUF5358 domain-containing protein -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 45974.49 Da        Isoelectric Point: 10.1740

>NTDB_id=158582 ACT74_RS07010 WP_005567968.1 1493456..1494679(+) (pilC) [Aggregatibacter actinomycetemcomitans strain VT1169]
MIKLKLFQWRAVNRLQQKQKGLIVAETEAMAQQQLLSCGLQNIKLQQNWQFSHKPKNADICTLLSQLATLLQAAVPLKNS
LQILLQNCTNIALNRWLRCLLQEIESGLAFSQALEQQGLYLTYQERQLIQVGEMTGKLAAVCHEIAQHKQQALALQRKIQ
KILLYPLLVLGISLILTALLLLFIVPQFAAMYDNSNAQLPVFTQVLLALSQGLQGYWFALLMFIALTVALIRFRLKHSPW
LNRQKNRLINSIPLLNRIVQLSRLVGFSHSLFLMLQAGIPLNQALQSFLPKQQSWQTKPQQQGDWLLIAGVQSALHWIQQ
GYPFSASVSGQIFPPAAQQMLQVGEQSGQLPKMLQFIANDHQQQLDHQIDLLSQMLEPLLMVIIGGLIGLIMLGMYLPIF
NMGSLVQ

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=158582 ACT74_RS07010 WP_005567968.1 1493456..1494679(+) (pilC) [Aggregatibacter actinomycetemcomitans strain VT1169]
ATGATTAAATTGAAACTGTTTCAATGGCGCGCCGTTAATCGACTACAGCAAAAACAAAAAGGCTTAATCGTGGCGGAAAC
GGAGGCGATGGCACAACAACAGCTGCTTTCATGCGGGTTGCAAAACATCAAATTACAACAAAACTGGCAATTTAGCCACA
AACCGAAAAATGCCGACATCTGCACGCTGCTTTCCCAACTGGCGACGCTGTTACAAGCCGCCGTGCCGCTGAAAAACAGC
CTGCAAATTTTATTGCAAAATTGTACCAATATTGCGTTGAATCGCTGGCTACGCTGCTTGCTACAGGAGATTGAAAGCGG
CTTAGCATTTTCTCAAGCATTGGAACAACAAGGTTTATACTTAACCTATCAGGAACGCCAACTGATTCAGGTGGGTGAAA
TGACAGGCAAACTTGCCGCCGTTTGTCATGAAATCGCACAACATAAACAACAGGCGCTGGCGTTGCAGCGTAAAATTCAG
AAAATCCTGCTTTATCCGTTGCTGGTGCTCGGAATCTCATTGATTTTGACCGCACTTTTATTGCTGTTCATCGTGCCGCA
ATTTGCCGCCATGTATGACAACAGCAACGCGCAACTGCCCGTGTTCACGCAGGTTTTACTAGCCCTTTCCCAAGGCTTGC
AGGGTTATTGGTTCGCGCTGCTCATGTTTATTGCGCTGACCGTGGCGTTAATTCGCTTTCGCCTCAAACATTCGCCTTGG
CTTAACCGACAAAAAAACCGGCTGATTAACAGTATTCCGCTACTTAATCGTATCGTACAACTCTCCCGTTTAGTGGGATT
CAGTCACAGCTTGTTTTTGATGTTACAGGCAGGTATTCCGCTGAATCAGGCGCTACAATCTTTCCTACCGAAACAACAAA
GCTGGCAAACTAAACCGCAGCAGCAAGGGGATTGGCTGCTTATTGCGGGAGTGCAATCGGCACTGCATTGGATTCAACAA
GGCTATCCGTTCTCCGCCAGCGTAAGCGGACAAATCTTCCCGCCGGCGGCACAACAAATGCTGCAAGTCGGCGAACAAAG
CGGTCAATTGCCGAAAATGCTGCAATTTATCGCCAACGATCATCAGCAACAATTGGATCACCAAATCGATCTACTGTCAC
AAATGCTGGAACCGTTGTTGATGGTAATTATCGGCGGGCTGATCGGCTTGATTATGCTCGGTATGTATTTACCGATTTTC
AACATGGGCTCGCTGGTACAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)

Type II secretion system (T2SS), protein F (T2SSF)

(267-398)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

63.275

99.017

0.627
  pilC Haemophilus influenzae 86-028NP

62.531

99.017

0.619
  pilC Glaesserella parasuis strain SC1401

39.401

98.526

0.388

Multiple sequence alignment